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Somewhere out beyond the edge of the universe there is a library that contains an infinite number of books, each one the story of another reality. One tells the story of your life as it is, along with another book for the other life you could have lived if you had made a different choice at any point in your life. While we all wonder how our lives might have been, what if you had the chance to go to the library and see for yourself? Would any of these other lives truly be better? In The Midnight Library, Nora Seed finds herself faced with this decision.

Some doors are locked for a reason.... While 11-year-old Nora Davis was up in her bedroom doing homework, she had no idea her father was killing women in the basement. Until the day the police arrived at their front door. Decades later, Nora's father is spending his life behind bars, and Nora is a successful surgeon with a quiet, solitary existence. Nobody knows her father was a notorious serial killer. And she intends to keep it that way. Then Nora discovers one of her young female patients has been murdered.

Newlyweds Tricia and Ethan are searching for the house of their dreams. But when they visit the remote manor that once belonged to Dr. Adrienne Hale, a renowned psychiatrist who vanished without a trace four years earlier, a violent winter storm traps them at the estate… with no chance of escape until the blizzard comes to an end. In search of a book to keep her entertained until the snow abates, Tricia happens upon a secret room. One that contains audio transcripts from every single patient Dr. Hale has ever interviewed.

In 2015, Mary Yoder returned home from the chiropractic center that she operated with her husband, Bill, complaining that she felt unwell. Mary, health-conscious and vibrant, was suddenly vomiting, sweating, and weak. Doctors in the ER and ICU were baffled as to the cause of her rapidly progressing illness. Her loved ones - including Bill and their children, Adam, Tamryn, and Liana - gathered in shock to say good-bye. In the weeks that followed Mary's death, the grief-stricken family received startling news from the medical examiner: Mary had been deliberately poisoned with colchicine.