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00:52 Intro: definition and prompts

04:25 Intro to Case 1: Haemophilia B, 3rd dose of Venefix, Anaphylaxis

06:03 Intro to Case 2: Severe Haemophilia A, joint bleed, non-responsive to emergency Factor VIII

07:30 Initial screening tests

• NB: Inhibitors: Time Dependent vs. Immediate Acting

14:54 Flash examples of Mixing Study importance

16:35 Bethesda Assay

**Bethesda Studios made the Elder Scrolls and Fallout games: they Inhibit Haider from doing any work**

28:45 Bethesda Assay Summary

30:00 Nijmegen Modification of Bethesda Assay

34:30 Heat Treatment of Bethesda Assay

36:25 ELISA Assay

40:30 Auto vs Allo Antibodies

42:00 Kinetics of a Time Dependent Inhibtor

44:45 Case 1 results

45:50 Case 2 results

51:00 Case 3 (real-life scenario): young girl, subdural bleed after fall, deranged clotting found incidentally

59:30 Summary

'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.

Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.

Email: basicstobrilliancehaem@gmail.com

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X: @basics_2_brill

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