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Obgyn: Hyperemesis Gravidarum: Free MSRA Podcast

Obgyn: Hyperemesis Gravidarum: Free MSRA Podcast

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 🎙️ Episode Title: Hyperemesis Gravidarum — Severe Morning Sickness DemystifiedWelcome to another episode of The Deep Dive, where we break down complex clinical topics into crystal-clear essentials. Today’s focus: Hyperemesis Gravidarum (HG) — a condition that’s way more than just morning sickness 🤢Ideal for MSRA prep or brushing up your obs and gynae knowledge!🧠 Key Learning Points📌 DefinitionSevere nausea and vomiting in pregnancy causing >5% weight loss, dehydration, electrolyte imbalance, and ketosis📌 Pathophysiology• Thought to be multifactorial• Major role: High levels of HCG• Other factors: impaired gastric motility, heightened brainstem sensitivity, and neurological input📌 Risk Factors• Previous HG• Multiple pregnancies 👶👶• Female fetus or mixed gender twins• History of motion sickness, migraines• Hyperthyroidism, molar pregnancy, obesity• 🚬 Smoking reduces risk (counterintuitive!)📌 Clinical Features• Severe vomiting and persistent nausea• Weight loss >5%, dehydration (dry mouth, dizziness, tachycardia)• Ketones in urine, possible electrolyte imbalance• May need hospitalisation📌 Differential Diagnosis• Morning sickness• UTI• Gastroenteritis• Appendicitis• Liver disease📌 Investigations• Bloods: FBC, U&Es, LFTs, TFTs• Urinalysis: Ketones, UTI screen• Ultrasound: rule out molar pregnancy, confirm intrauterine location• PUQE Score 🧮 to assess severity📌 Management• IV fluids, antiemetics, nutritional support• First-line: cyclizine, promethazine, prochlorperazine• Second-line: ondansetron, metoclopramide, domperidone• Third-line: corticosteroids, PPIs• Thiamine (B1) always before glucose to prevent Wernicke’s encephalopathy• Consider thromboprophylaxis for immobile patients📌 Referral Criteria• Unable to tolerate fluids/meds• Persistent ketonuria• Weight loss >5%• Suspected complications (e.g., UTI, co-morbidities like diabetes)📌 Prognosis• Often improves by 20 weeks• Recurrence likely in future pregnancies• Good recovery if well-managed📌 Complications• Maternal: dehydration, electrolyte issues, Wernicke’s, Mallory-Weiss tears, kidney injury, mental health effects• Fetal: low birth weight, preterm birth, especially in poorly managed cases📚 Resources for Hyperemesis Gravidarum📝 Revision Notes:https://www.passthemsra.com/topic/hyperemesis-gravidarum-revision-notes/🧠 Flashcards:https://www.passthemsra.com/topic/hyperemesis-gravidarum-flashcards/❓ Accordion Q&A Notes:https://www.passthemsra.com/topic/hyperemesis-gravidarum-accordion-qa-notes/🔥 Rapid Fire Quiz:https://www.passthemsra.com/topic/hyperemesis-gravidarum-rapid-quiz/✅ Quiz Access:https://www.passthemsra.com/quizzes/hyperemesis-gravidarum/🎓 Course Home:https://www.passthemsra.com/courses/obstetrics-and-gynaecology-for-the-msra/🎧 Whether you're revising for the MSRA, reviewing obs & gynae, or just want clinical clarity — this is a must-listen. Dive deep, retain more, revise smarter.#MSRA #MSRARevision #HyperemesisGravidarum #ObsAndGynae #MSRAFlashcards #MSRAQuiz #WernickesEncephalopathy #PregnancyComplications #PUQEscore #MedicalPodcast #PassTheMSRA #FreeMSRAResources #NauseaInPregnancy #EvidenceBasedMedicine #MSRAHighYield #ClinicalMedicine
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