Dr. Thomas Weims, Professor at UC Santa Barbara, shares his revolutionary findings on treating polycystic kidney disease through ketogenic interventions. After 25 years of research, his lab accidentally discovered that ketosis dramatically halts and even reverses PKD progression—something previously thought impossible. The medical establishment had long maintained that PKD, a genetic disease affecting 600,000 Americans, was untreatable through dietary means. Yet Weims' research demonstrates that beta-hydroxybutyrate (BHB), the primary ketone produced during ketosis, shows more potent effects than any pharmacological intervention his team tested. In a groundbreaking clinical trial, patients on a ketogenic diet experienced improved kidney function and reduced kidney volume in just three months—the first time such reversal has ever been documented in PKD. Weims explains the science behind this therapeutic approach, how it challenges entrenched medical dogma, and why this metabolic therapy may benefit all forms of chronic kidney disease. This conversation exposes how decades of medical education about diet and kidney health have been based on hypothetical papers rather than clinical evidence, offering hope to millions suffering from progressive kidney conditions.

BIG IDEA

"What we found more recently is that the progression of polycystic kidney disease is not really driven by gene mutations as previously thought—a patient inherits a bad gene, but that doesn't necessarily mean they will have rapidly progressing PKD."

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