On a leafy suburban street in Dublin, beautiful, poised Stella Greene lives with her successful husband, Matt. They're the perfect couple in every way, and Stella appears to have it all. Next door, at number 72, however, lives Rea Brady. Gruff, bad tempered and rarely seen besides the twitching of her net curtains, rumour has it she's lost it all...including her marbles, if you believe the neighbourhood gossip. But appearances can be deceiving, and when Stella and Rea's worlds collide they realise they have much in common.

Adam adores Emily. Emily thinks Adam’s perfect, the man she thought she’d never meet. Emily chose Adam, but she didn’t choose his mother, Pammie. There’s nothing a mother wouldn’t do for her son, and now Emily is about to find out just how far Pammie will go to get what she wants: Emily gone forever.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.

In 1918, after four harrowing years on the Western Front, Tom Sherbourne returns to Australia to take a job as the lighthouse keeper on remote Janus Rock. To this isolated island, where the supply boat comes only four times a year and shore leaves are granted every other year at best, Tom brings a young, bold, and loving wife, Isabel. Three years later, after two miscarriages and one stillbirth, the grieving Isabel is tending the grave of her newly lost infant when she hears a baby’s cries on the wind. A boat has washed up on shore carrying a dead man and a living baby.

Born on a farm outside Edinburgh in the mid-19th century, Agnes Watt is embraced by family, community, and tradition. Her youthful hopes and dreams are quashed but she falls in love and marries William Miller, a Gordon Highlander. Life spirals into dark places as the couple become ensnared in the nightmare that descended on the Scottish working class during the industrial revolution. The triumphs of the great Victorian era came at an appalling human cost and Agnes fights against disease and grinding poverty.

When Cissy Ryan’s real mother comes to claim her from the workhouse, it’s not how she imagined. Her family’s tumbledown cottage has ice on the inside of its windows and is in an isolated, poverty-stricken village in the muddy Irish countryside. But when Cissy is allowed to help neighbour Colm Doyle and his horse named Blue on their milk round one morning, Cissy starts to feel as though friendship could get her through anything.

Born in rural Palestine, just before the dawn of the 20th century, Miriam adores her father and is certain his love will protect her, but she soon finds that tradition overrides love. Uprooted by war, Miriam enters a world where the old constraints slip away with thrilling and disastrous results. Miriam's rebellious daughter, Nadia, is thrilled with the opportunity for a modern life that her elite education provides. But when she falls in love with an outsider, the clan reins her back with a shocking finality.

Susie did something that she knows she will always regret: giving her baby son up for adoption, to keep her infidelity secret from her family. Louise, Susie's daughter, feels the effects of that decision echoing down through the years - her mother has always been difficult, too strict with her but not strict enough with her sister, Grace, who is wild and out of control. And Danny, Susie's husband, adores her but has always sensed something wrong at the heart of their marriage.

In the autumn of 1940, four children meet on a train. Behind them is London, under heavy aerial attack; ahead of them is a ship bound for the safe shores of Canada. Arthur has promised his mother not to let his little brother, Philip, out of his sight. Pippa and Dora are on their own: polar opposites, brought together by the adventure of a lifetime. But disaster strikes mid-Atlantic, and in the chaos one of the children makes a choice that will determine the course of their lives forever.

London 1940. As the war rages in Europe, Rose Brown steps on board a ship bound for America, hoping to escape the danger. She's frightened, but her widowed mammy and three sisters in Ireland need the money she earns as nanny to the rich Townsend family. But while Rose plays with baby Sarah in the salty spray on deck, disaster strikes, and the ocean liner begins to sink. In the chaos, Rose and the baby are separated from the family.

East London, 1888 - a city apart. A place of shadow and light where thieves, whores, and dreamers mingle, where children play in the cobbled streets by day and a killer stalks at night, where bright hopes meet the darkest truths. Here, by the whispering waters of the Thames, Fiona Finnegan, a worker in a tea factory, hopes to own a shop one day, together with her lifelong love, Joe Bristow, a costermonger's son. With nothing but their faith in each other to spur them on, Fiona and Joe struggle, save, and sacrifice to achieve their dreams.

London, 1942: Thirteen-year-old Nell and five-year-old Olive are being sent away from home to escape the devastation of the East End during the Blitz. Leaving behind their beloved mother and brothers, they don’t know if they will ever see them again. As the sisters adjust to their new life in a close-knit Welsh village, they gradually find hope in the friendships they make. And Nell kindles a special bond with fellow evacuee Jimmy, who makes her smile even at the hardest of times. But when little Olive’s safety is threatened, Nell makes a decision that will change their lives forever.

As Britain stands alone against a monstrous enemy, the inhabitants of Pearl Street face hardship and heartbreak with courage and humour. The war touches each of them in a different way: for Annie Poulson, a widow, it means never-ending worry when her twin boys are called up and sent to France; Sheila Reilly's husband, Cal, faces the terror of U-Boat attacks; Eileen Costello is liberated from a bitter, loveless marriage when her husband is sent to Egypt.

Young and desperately in love, Merrin had the whole world ahead of her. But just as her new life was about to start, the ground beneath her feet was cruelly swept away. Devastated by the humiliation, she ran far away from the beloved fishing village she had always called home to lick her wounds and escape her gossiping friends and neighbors. It hasn’t been easy, but six years later Merrin has forged a new life for herself far from the sea, burying the impulsive girl she once was.

Dottie and Mary forged a friendship over a bag of penny sweets when they were eight years old. They've shared everything together since then. Now, at seventeen, they're both shopgirls working at Woolworths. As they go out in the world in pursuit of love and happiness and life becomes more complicated, the simplicity of their childhood dissolves. The heady excitement of first love will consume them both, but the pain of unintentional betrayal will test their friendship.