It is 997 CE, the end of the Dark Ages. England is facing attacks from the Welsh in the west and the Vikings in the east. Those in power bend justice according to their will, regardless of ordinary people and often in conflict with the king. Without a clear rule of law, chaos reigns. In these turbulent times, three characters find their lives intertwined.

Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

Adelaide Henry carries an enormous steamer trunk with her wherever she goes. It’s locked at all times. Because when the trunk opens, people around Adelaide start to disappear. The year is 1915, and Adelaide is in trouble. Her secret sin killed her parents, forcing her to flee California in a hellfire rush and make her way to Montana as a homesteader.

Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, feeling no certain calling despite a lively faith, he turns to the profession of surgeon, training in Paris and then hanging out his sign in Oxford. A local lord asks him to track the killer of a young woman whose bones have been found in the castle cesspit. She is identified as the impetuous missing daughter of a local blacksmith, and her young man, whom she had provoked very publicly, is in due course arrested and sentenced at the Oxford assizes.

Hennie Comfort is 86 and has lived in the mountains of Middle Swan, Colorado since before it was Colorado. Nit Spindle is just 17 and newly married. She and her husband have just moved to the high country in search of work. It's 1936 and the depression has ravaged the country and Nit and her husband have suffered greatly. Hennie notices the young woman loitering near the old sign outside of her house that promises "Prayers For Sale".

When Margaret and her husband Hal bought the large Victorian house on Hawthorn Street—for sale at a surprisingly reasonable price—they couldn’t believe they finally had a home of their own. Then they discovered the hauntings. Every September, the walls drip blood. The ghosts of former inhabitants appear, and all of them are terrified of something that lurks in the basement. Most people would flee. Margaret is not most people. Margaret is staying.

St. Vincent's Orphanage for Boys. Turn of the century, in a remote valley in Pennsylvania. Here, under the watchful eyes of several priests, thirty boys work, learn, and worship. Peter Barlow, orphaned as a child by a gruesome murder, has made a new life here. As he approaches adulthood, he has friends, a future...a family. Then, late one stormy night, a group of men arrive at their door, one of whom is badly wounded, occult symbols carved into his flesh. His death releases an ancient evil that spreads like sickness, infecting St. Vincent's and the children within.

The Romans invaded Britannia in AD 43 confident of victory. They swept through a divided and ill-equipped enemy, scattered across tough terrain. But one man was not prepared to surrender. Caratacus - quick-witted youngest son of a a tribal king - had been trained from birth to be a warrior of power and grit. Sent to be schooled by the Druids in his boyhood, his training meant that an already strong and cunning prince returned to his father's kingdom as a war machine.

England, 1364: When married off at aged twelve to an elderly farmer, brazen redheaded Eleanor quickly realizes it won’t matter what she says or does, God is not on her side—or any poor woman’s for that matter. But then again, Eleanor was born under the joint signs of Venus and Mars, making her both a lover and a fighter.

The Little Stranger follows the strange adventures of Dr. Faraday, the son of a maid who has built a life of quiet respectability as a country doctor. One dusty postwar summer in his home of rural Warwickshire, he is called to a patient at Hundreds Hall. Home to the Ayres family for more than two centuries, the Georgian house, once grand and handsome, is now in decline - its masonry crumbling, its gardens choked with weeds, the clock in its stable yard permanently fixed at 20 to nine.

It is 1547, and Scotland has been humiliated by an English invasion and is threatened by machinations elsewhere beyond its borders, but it is still free. Paradoxically, her freedom may depend on a man who stands accused of treason. He is Francis Crawford of Lymond, a scapegrace nobleman of crooked felicities and murderous talents, possessed of a scholar's erudition and a tongue as wicked as a rapier. In The Game of Kings, this extraordinary antihero returns to the country that has outlawed him to redeem his reputations even at the risk of his life.

For fifteen years FitzChivalry Farseer has lived in self-imposed exile, assumed to be dead by almost all who once cared about him. But now, into his isolated life, visitors begin to arrive: Fitz's mentor from his assassin days; a hedge-witch who foresees the return of a long-lost love; and the Fool, the former White Prophet, who beckons Fitz to fulfill his destiny. Then comes the summons he cannot ignore. Prince Dutiful, the young heir to the Farseer throne, has vanished.

Winter lasts most of the year at the edge of the Russian wilderness, and in the long nights, Vasilisa and her siblings love to gather by the fire to listen to their nurse’s fairy tales. Above all, Vasya loves the story of Frost, the blue-eyed winter demon. Wise Russians fear him, for he claims unwary souls, and they honor the spirits that protect their homes from evil. Then Vasya’s widowed father brings home a new wife from Moscow. Fiercely devout, Vasya’s stepmother forbids her family from honoring their household spirits, but Vasya fears what this may bring.

To escape a lifetime of poverty, mercenary Sir Benedict Palmer agrees to one final, lucrative job: help King Henry II's knights seize the traitor Archbishop Thomas Becket at Canterbury Cathedral. But what begins as a clandestine arrest ends in cold blooded murder. And when Fitzurse, the knights' ringleader, kidnaps Theodosia, a beautiful young nun who witnessed the crime, Palmer can sit silently by no longer.

It's 1945: When the critically wounded Captain Cooper Ravenal is brought to a private hospital on Manhattan's Upper East Side, young Dr. Kate Schuyler is drawn into a complex mystery that connects three generations of women in her family to a single extraordinary room in a Gilded Age mansion. Who is the woman in Captain Ravenel's portrait miniature who looks so much like Kate? And why is she wearing the ruby pendant handed down to Kate by her mother?