Kirsten Raymonde will never forget the night Arthur Leander, the famous Hollywood actor, had a heart attack on stage during a production of King Lear. That was the night when a devastating flu pandemic arrived in the city, and within weeks, civilization as we know it came to an end.

Candace Chen, a millennial drone self-sequestered in a Manhattan office tower, is devoted to routine. With the recent passing of her Chinese immigrant parents, she’s had her fill of uncertainty. She’s content just to carry on: She goes to work, troubleshoots the teen-targeted Gemstone Bible, watches movies in a Greenpoint basement with her boyfriend. So Candace barely notices when a plague of biblical proportions sweeps New York.

Young Hiram Walker was born into bondage. When his mother was sold away, Hiram was robbed of all memory of her - but was gifted with a mysterious power. Years later, when Hiram almost drowns in a river, that same power saves his life. This brush with death births an urgency in Hiram and a daring scheme: to escape from the only home he’s ever known. So begins an unexpected journey that takes Hiram from the corrupt grandeur of Virginia’s proud plantations to desperate guerrilla cells in the wilderness, from the coffin of the South to dangerously idealistic movements in the North.

“It happened fast. Thirty-two minutes for one world to die, another to be born". An epic and gripping tale of catastrophe and survival, The Passage is the story of Amy - abandoned by her mother at the age of six, pursued, and then imprisoned by the shadowy figures behind a government experiment of apocalyptic proportions. But Special Agent Brad Wolgast, the lawman sent to track her down, is disarmed by the curiously quiet girl and risks everything to save her. As the experiment goes nightmarishly wrong, Wolgast secures her escape - but he can’t stop society’s collapse.

Twelve-year-old Bird Gardner lives a quiet existence with his loving father, a former linguist who now shelves books in a university library. His mother, Margaret, a Chinese American poet, left without a trace when he was nine years old. He doesn’t know what happened to her—only that her books have been banned—and he resents that she cared more about her work than about him.

"Ninety-five days, and then I'll be safe. I wonder whether the procedure will hurt. I want to get it over with. It's hard to be patient. It's hard not to be afraid while I'm still uncured, though so far the deliria hasn't touched me yet. Still, I worry. They say that in the old days, love drove people to madness. The deadliest of all deadly things: It kills you both when you have it and when you don't."

On a damp October night, beautiful young Ashley Cordova is found dead in an abandoned warehouse in lower Manhattan. Though her death is ruled a suicide, veteran investigative journalist Scott McGrath suspects otherwise. As he probes the strange circumstances surrounding Ashley’s life and death, McGrath comes face-to-face with the legacy of her father: the legendary, reclusive, cult-horror-film director Stanislas Cordova - a man who hasn’t been seen in public for more than 30 years.

Imogene is young, beautiful . . . and dead, waiting in the Rosebud Theater one afternoon in 1945. . . . Francis was human once, but now he's an eight-foot-tall locust, and everyone in Calliphora will tremble when they hear him sing. . . . John is locked in a basement stained with the blood of half a dozen murdered children, and an antique telephone, long since disconnected, rings at night with calls from the dead.

An intricate tale of love, haunting memories, and renewal, Second Glance begins in current-day Vermont, where an old man puts a piece of land up for sale and unintentionally raises protest from the local Abenaki Indian tribe, who insist it's a burial ground. When odd, supernatural events plague the town of Comtosook, a ghost hunter is hired by the developer to help convince the residents that there's nothing spiritual about the property.

In this gripping first novel, a young girl, orphaned when her mother murders an ex-lover, endures the shuffle of a foster child's life. Oprah enjoyed her book club pick so much that she narrates the audiobook edition!

Browse more Oprah Picks.

From the perspective of those who live in Herot Hall, the suburb is a paradise. Picket fences divide buildings—high and gabled—and the community is entirely self-sustaining. Each house has its own fireplace, each fireplace is fitted with a container of lighter fluid, and outside—in lawns and on playgrounds—wildflowers seed themselves in neat rows. But for those who live surreptitiously along Herot Hall’s periphery, the subdivision is a fortress guarded by an intense network of gates, surveillance cameras, and motion-activated lights.

Thirteen-year-old Caroline and her father have lived for four years on the outskirts of Portland, Oregon, in Forest Park. He has homeschooled her using encyclopedias and books from the library while also teaching her a rigid code of behavior that enables them to survive in this wilderness. Yet one small mistake allows the authorities to discover them. Their forced relocation to a horse farm outside of the city becomes only a brief respite to their deeper flight from a world that can't understand them.

Seven-year-old Chula and her older sister, Cassandra, enjoy carefree lives thanks to their gated community in Bogotá, but the threat of kidnappings, car bombs, and assassinations hover just outside the neighborhood walls, where the godlike drug lord Pablo Escobar continues to elude authorities and capture the attention of the nation. When their mother hires Petrona, a live-in-maid from the city's guerrilla-occupied slum, Chula makes it her mission to understand Petrona's mysterious ways.

On the three-year anniversary of the tornado that orphaned the McCloud children, a cosmetics factory outside of Mercy is bombed, and the lab animals trapped within are released. Tucker reappears, injured from the blast, and seeks the help of nine-year-old Cora. Caught up in the thrall of her charismatic brother, whom she has desperately missed, Cora agrees to accompany Tucker on a cross-country mission to make war on human civilization. Cora becomes her brother's unwitting accomplice, taking on a new identity while engaging in acts of escalating violence.

This astonishing novel was chosen as a Best Book of the Year by the Los Angeles Times, Entertainment Weekly, Publisher's Weekly and Newsweek. Contained within is the story of Edgar Mint, the half-Apache, mostly orphaned child who overcomes a serious childhood injury to embark on a life of tragedies, including a boarding school for Native Americans and a dysfunctional Mormon foster family.