“Any story that starts will also end.” As a writer, Ann Patchett knows what the outcome of her fiction will be. Life, however, often takes turns we do not see coming. Patchett ponders this truth in these wise essays that afford a fresh and intimate look into her mind and heart.

The irascible A. J. Fikry, owner of Island Books - the only bookstore on Alice Island - has already lost his wife. Now his most prized possession, a rare book, has been stolen from right under his nose in the most embarrassing of circumstances. The store itself, it seems, will be next to go. One night upon closing, he discovers a toddler in his children’s section with a note from her mother pinned to her Elmo doll: I want Maya to grow up in a place with books and among people who care about such kinds of things. I love her very much, but I can no longer take care of her.

In 1985, Yale Tishman, the development director for an art gallery in Chicago, is about to pull off an amazing coup, bringing in an extraordinary collection of 1920s paintings as a gift to the gallery. Yet as his career begins to flourish, the carnage of the AIDS epidemic grows around him. One by one, his friends are dying and after his friend Nico's funeral, the virus circles closer and closer to Yale himself. Soon the only person he has left is Fiona, Nico's little sister.

Nantucket writer Madeline King couldn't have picked a worse time to have writer's block. Her deadline is looming, her bills are piling up, and inspiration is in short supply. Madeline's best friend, Grace, is hard at work transforming her garden into the envy of the island with the help of a ruggedly handsome landscape architect. Before she realizes it, Grace is on the verge of a decision that will irrevocably change her life. Could Grace's crisis be Madeline's salvation?

The Latecomer follows the story of the wealthy, New York City-based Oppenheimer family, from the first meeting of parents Salo and Johanna, under tragic circumstances, to their triplets born during the early days of IVF. As children, the three siblings—Harrison, Lewyn, and Sally—feel no strong familial bond and cannot wait to go their separate ways, even as their father becomes more distanced and their mother more desperate. When the triplets leave for college, Johanna, faced with being truly alone, makes the decision to have a fourth child.

From marriage, infidelity, and the mayhem of motherhood to scandal, tragedy, and illness - three women seek peace and comfort in Nantucket as they cope with life's challenges. Three women - burdened with small children, unwieldy straw hats, and some obvious emotional issues - tumble onto the Nantucket airport tarmac one hot June day. Vicki is trying to sort through the news that she has a serious illness. Her sister, Brenda, has just left her job after being caught in an affair with a student. And their friend Melanie, after seven failed in vitro attempts, is pregnant at last.

Grace Reinhart Sachs is living the only life she ever wanted for herself. Devoted to her husband, a pediatric oncologist at a major cancer hospital, their young son Henry, and the patients she sees in her therapy practice, her days are full of familiar things: She lives in the very New York apartment in which she was raised, and sends Henry to the school she herself once attended. Dismayed by the ways in which women delude themselves, Grace is also the author of a book You Should Have Known, in which she cautions women to really hear what men are trying to tell them.

To be admired by someone we admire - we all yearn for this: the private, electrifying pleasure of being singled out by someone of esteem. But sometimes it can also mean entry to a new kind of life, a bigger world. Greer Kadetsky is a shy college freshman when she meets the woman she hopes will change her life. Faith Frank, dazzlingly persuasive and elegant at 63, has been a central pillar of the women’s movement for decades, a figure who inspires others to influence the world.

Jade believes she must get out of her neighborhood if she's ever going to succeed. Her mother says she has to take every opportunity. She has. She accepted a scholarship to a mostly-white private school and even Saturday morning test prep opportunities. But some opportunities feel more demeaning than helpful. Like an invitation to join Women to Women, a mentorship program for "at-risk" girls. Except really, it's for black girls. From "bad" neighborhoods. But maybe there are some things Jade could show these successful women about the real world and finding ways to make a real difference.

Marie Bostwick weaves the unforgettable story of four very different women whose paths cross, changing their lives forever. It’s a long way from Fort Worth, Texas, to New Bern, Connecticut, yet it only takes a day in the charming Yankee town to make Evelyn Dixon realize she’s found her new home. The abrupt end of her marriage was Evelyn’s wake-up call to get busy chasing her dream of opening a quilt shop. Finding a storefront is easy enough; starting a new life isn’t....

People are drawn to libraries for all kinds of reasons. Most come for the books themselves, of course; some come to borrow companionship. For head librarian Kit, the public library in Riverton, New Hampshire, offers what she craves most: peace. Here, no one expects Kit to talk about the calamitous events that catapulted her out of what she thought was a settled, suburban life. She can simply submerge herself in her beloved books and try to forget her problems. But that changes when 15-year-old, home-schooled Sunny gets arrested for shoplifting a dictionary.

The stories in Fresh Complaint explore equally rich­­—­­and intriguing—territory. Ranging from the bitingly reproductive antics of “Baster” to the dreamy, moving account of a young traveler’s search for enlightenment in “Air Mail” (selected by Annie Proulx for Best American Short Stories), this collection presents characters in the midst of personal and national emergencies. We meet a failed poet who, envious of other people’s wealth during the real-estate bubble, becomes an embezzler; a clavichordist whose dreams of art founder under the obligations of marriage and fatherhood.

David Hedges’ life is coming apart at the seams. His job helping San Francisco rich kids get into the colleges of their (parents’) choice is exasperating; his younger boyfriend has left him; and the beloved carriage house he rents is being sold. His solace is a Thai takeout joint that delivers 24/7.

In a historic farmhouse outside Boston, 70-year-old Percy Darling is settling happily into retirement: Reading novels, watching old movies, and swimming naked in his pond. His routines are disrupted, however, when he is persuaded to let a locally beloved preschool take over his barn. As Percy sees his rural refuge overrun by children, parents, and teachers, he must reexamine the solitary life he has made in the three decades since the sudden death of his wife. No longer can he remain aloof from his community.

Charles Marlow is a Seattle English teacher who instructs his students to expand their worlds through language. Lately, however, with one child off to college and the pressure from his ex-wife to make plans for their severely autistic son who's about to age out of the system, he prefers the company of the ghosts he turns up in the storage boxes in his crawl space.