By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

Rosalind Franklin was what can only be called an overlooked genius. Although she was not fully credited for the feat at the time, her work led to major breakthroughs in our understanding of DNA. In fact, she took the first X-ray photo of DNA in all of its double helix glory. By the time her former colleagues were being showered with accolades for results they made at least partially based on her findings, Franklin would not be around to see it. Sadly, it’s believed that her use of X-ray equipment gave her terminal cancer, cutting her life short at age 37.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

Rosalind Franklin has always been an outsider - brilliant, but different. Whether working at the laboratory she adored in Paris or toiling at a university in London, she feels closest to the science, those unchanging laws of physics and chemistry that guide her experiments. When she is assigned to work on DNA, she believes she can unearth its secrets. Rosalind knows if she just takes one more X-ray picture - one more after thousands - she can unlock the building blocks of life.

The audiobook is focused and high-yield, covering the most important topics you might expect to learn in a typical undergraduate organic chemistry course. The material is accurate, up-to-date, and broken down into bite-sized chapters. There are key takeaways following each chapter to drive home key points and quizzes to review commonly tested questions.

Cities and countries engulfed by panic and death, desperate for vaccines but fearful of what inoculation may bring. This is what the world has just gone through with Covid-19. But as Simon Schama shows in his epic history of vulnerable humanity caught between the terror of contagion and the ingenuity of science, it has happened before.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

Paulo Coelho's enchanting novel has inspired a devoted following around the world. This story, dazzling in its simplicity and wisdom, is about an Andalusian shepherd boy named Santiago who travels from his homeland in Spain to the Egyptian desert in search of treasure buried in the Pyramids. Along the way he meets a Gypsy woman, a man who calls himself king, and an Alchemist, all of whom point Santiago in the direction of his quest.

With insight, humor, formal invention, and lyricism, in A Man of Two Faces Viet Thanh Nguyen rewinds the film of his own life. He expands the genre of personal memoir by acknowledging larger stories of refugeehood, colonization, and ideas about Vietnam and America, writing with his trademark sardonic wit and incisive analysis, as well as a deep emotional openness about his life as a father and a son.

J. Robert Oppenheimer was one of the iconic figures of the 20th century, a brilliant physicist who led the effort to build the atomic bomb but later confronted the moral consequences of scientific progress. When he proposed international controls over atomic materials, opposed the development of the hydrogen bomb, and criticized plans for a nuclear war, his ideas were anathema to powerful advocates of a massive nuclear buildup during the anti-Communist hysteria of the early 1950s.

Barely 50 years ago a computer was a gargantuan, vastly expensive thing that only a handful of scientists had ever seen. The world's brightest engineers were stymied in their quest to make these machines small and affordable until the solution finally came from two ingenious young Americans. Jack Kilby and Robert Noyce hit upon the stunning discovery that would make possible the silicon microchip, a work that would ultimately earn Kilby the Nobel Prize for physics in 2000.

Rosalind Franklin was what can only be called an overlooked genius. Although she was not fully credited for the feat at the time, her work led to major breakthroughs in our understanding of DNA. In fact, she took the first X-ray photo of DNA in all of its double helix glory. By the time her former colleagues were being showered with accolades for results they made at least partially based on her findings, Franklin would not be around to see it. Sadly, it’s believed that her use of X-ray equipment gave her terminal cancer, cutting her life short at age 37.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

It is 1919 and Elizabeth Hughes, the 11-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to 45 pounds, skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition, and fistfights.

Throughout history, scientists have come up with theories and ideas that just don't seem to make sense. These we call paradoxes. The paradoxes Al-Khalili offers are drawn chiefly from physics and astronomy and represent those that have stumped some of the finest minds. With elegant explanations that bring the listener inside the mind of those who've developed them, Al-Khalili helps us to see that, in fact, paradoxes can be solved if seen from the right angle.

Two of the boldest and most creative scientists of all time were Michael Faraday (1791-1867) and James Clerk Maxwell (1831-1879). This is the story of how these two men - separated in age by 40 years - discovered the existence of the electromagnetic field and devised a radically new theory which overturned the strictly mechanical view of the world that had prevailed since Newton's time.

In one of the most exciting and accessible explanations of The Theory of Relativity in recent years, Professors Brian Cox and Jeff Forshaw go on a journey to the frontier of 21st century science to consider the real meaning behind the iconic sequence of symbols that make up Einstein's most famous equation, exploring the principles of physics through everyday life.

This urgent and eye-opening book makes the case that protecting humanity's future is the central challenge of our time. If all goes well, human history is just beginning. Our species could survive for billions of years - enough time to end disease, poverty, and injustice, and to flourish in ways unimaginable today. But this vast future is at risk. With the advent of nuclear weapons, humanity entered a new age, where we face existential catastrophes - those from which we could never come back.

In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared.

In this monumental history, Vaclav Smil provides a comprehensive account of how energy has shaped society, from pre-agricultural foraging societies through today's fossil fuel-driven civilization and offers listeners a magisterial overview of humanity's energy eras.

Levitt and co-author Stephen J. Dubner show that economics is, at root, the study of incentives: how people get what they want, or need, especially when other people want or need the same thing. In Freakonomics, they explore the hidden side of...well, everything. The inner working of a crack gang...the truth about real-estate agents...the secrets of the Klu Klux Klan. What unites all these stories is a belief that the modern world is even more intriguing than we think. All it takes is a new way of looking, and Freakonomics will redefine the way we view the modern world.

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.

The smartphones in our pockets and computers like brains. The vagaries of game theory and evolutionary biology. Nuclear weapons and self-replicating spacecrafts. All bear the fingerprints of one remarkable, yet largely overlooked, man: John von Neumann.

Gene Kranz was present at the creation of America's manned space program and was a key player in it for three decades. As a flight director in NASA's Mission Control, Kranz witnessed firsthand the making of history. He participated in the space program from the early days of the Mercury program to the last Apollo mission, and beyond. He endured the disastrous first years when rockets blew up and the United States seemed to fall further behind the Soviet Union in the space race.

Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on the Higgs boson and extra dimensions but now also on our deepest personal questions. Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void?

When AI expert and investigative journalist Karen Hao first began covering OpenAI in 2019, she thought they were the good guys. Founded as a nonprofit with safety enshrined as its core mission, the organization was meant, its leader Sam Altman told us, to act as a check against more purely mercantile, and potentially dangerous, forces. What could go wrong?