In 1960, Billie Valentine is a young housewife living in a sleepy Massachusetts suburb, treading water in a dull marriage and caring for two adopted daughters. Summers spent with the girls at their lakeside camp in Vermont are her one escape - from her husband's demands, from days consumed by household drudgery, and from the nagging suspicion that life was supposed to hold something different. Then a new family moves in across the street. Ted and Eva Wilson have three children and a fourth on the way, and their arrival reignites long-buried feelings in Billie.

In Two Rivers, Vermont, Harper Montgomery is living a life overshadowed by grief and guilt. Since the death of his wife twelve years earlier, Harper has narrowed his world to working at the local railroad and raising his daughter, Shelly. Still wracked with sorrow over his loss and plagued by his role in a brutal, long-ago crime, he wants only to make amends for his past mistakes. Then one day, a train derails in Two Rivers and Harper finds a chance at atonement.

Living peacefully in Vermont, Ryan Flannigan is shocked when a text from her oldest friend alerts her to a devastating news item. A controversial photo of her as a pre-teen has been found in the possession of a wealthy investor recently revealed as a pedophile and a sex trafficker—with an inscription to him from Ryan's mother on the back.

Camden, NJ, 1948. When 11 year-old Sally Horner steals a notebook from the local Woolworth's, she has no way of knowing that 52 year-old Frank LaSalle, fresh out of prison, is watching her, preparing to make his move. Accosting her outside the store, Frank convinces Sally that he’s an FBI agent who can have her arrested in a minute—unless she does as he says.

Dover, Massachusetts, 1969. Ginny Richardson's heart was torn open when her baby girl, Lucy, born with Down syndrome, was taken from her. Under pressure from his powerful family, her husband, Ab, sent Lucy away to Willowridge, a special school for the "feeble-minded". Ab tried to convince Ginny it was for the best. But two years later, when Ginny's best friend, Marsha, shows her a series of articles exposing Willowridge as a hell-on-earth - its squalid hallways filled with neglected children - she knows she can't leave her daughter there.

Cash and Sheriff Wheaton make for a strange partnership. He pulled her from her mother's wrecked car when she was three. He's kept an eye out for her ever since. It's a tough place to live - northern Minnesota along the Red River. Cash navigated through foster homes, and at 13 was working farms. She's tough as nails, five feet two inches, blue jeans, blue jean jacket, smokes Marlboros, drinks Bud Longnecks. Makes her living driving truck. Playing pool on the side.

Meet Dolores Price. She's 13, wise-mouthed but wounded, having bid her childhood goodbye. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the Mallomars, potato chips, and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly-up.

Eleven years ago, Lindsey Nash escaped into the night with her young daughter and left an abusive relationship. Her ex-husband, Andrew, was sent to jail and Lindsey started over with a new life. Now, Lindsey is older and wiser, with her own business and a teenage daughter who needs her more than ever. When Andrew is finally released from prison, Lindsey believes she has cut all ties and left the past behind her. But she gets the sense that someone is watching her, tracking her every move.

In the spring of 1981, the young Skinner siblings - fierce Renee, dreamy Caroline, golden boy Joe, and watchful Fiona - lose their father to a heart attack and their mother to a paralyzing depression, events that thrust them into a period they will later call “the Pause”. Caught between the predictable life they once led and an uncertain future that stretches before them, the siblings navigate the dangers and resentments of the Pause to emerge fiercely loyal and deeply connected. Two decades later, the Skinners find themselves again confronted with a family crisis....

Rachel Blum and Andy Landis are eight years old when they meet late one night in an ER waiting room. Born with a congenital heart defect, Rachel is a veteran of hospitals, and she's intrigued by the boy who shows up all alone with a broken arm. He tells her his name. She tells him a story. After Andy's taken back to the emergency room and Rachel's sent back to her bed, they think they'll never see each other again.

Caitlin can't afford to leave this dreamland, this half-sleeping state where everything and everyone can be kept at arm's length. Because then she'd have to face the ugly truth about her relationship with Rogerson: magnetic, fascinating--and very dangerous--Rogerson. What is it about Rogerson Biscoe...and why can't she leave him?

A boy and a girl who fall in love. Two families whose hopes collide with destiny. An extraordinary novel that offers a resonant new definition of what it means to be American. Arturo and Alma Rivera have lived their whole lives in Mexico. One day, their beautiful fifteen-year-old daughter, Maribel, sustains a terrible injury, one that casts doubt on whether she’ll ever be the same. And so, leaving all they have behind, the Riveras come to America with a single dream: that in this country of great opportunity and resources, Maribel can get better.

Living in Oklahoma with her maternal grandfather, Mary gets a new name and a new life. But she's haunted by the past: by the baby girls she's sure will come looking for her someday, by the mother she left behind, by the father who left her. Mary is a college student when her sisters start to get back in touch. With each subsequent reunion, her family becomes closer to whole again.

"Work hard. Do good. Be incredible!" is the advice Teresa Rae Wood shares with the listeners of her local radio show, Modern Pioneers, and the advice she strives to live by every day. She has fled a bad marriage and rebuilt a life with her children, Claire and Joshua, and their caring stepfather, Bruce. Their love for each other binds them as a family through the daily struggles of making ends meet. But when they received unexpected news that Teresa, only 38, is dying of cancer, their lives all begin to unravel and drift apart.

Addie Downs and Valerie Adler will be best friends forever. That’s what Addie believes after Valerie moves across the street when they’re both nine years old. But in their teenage years, Val is swept into the popular crowd. Flash-forward 15 years. Addie Downs lives alone in her parents’ house, caring for a troubled brother and trying to meet Prince Charming on the Internet. she opens her door to find her long-gone best friend standing there, a terrified look on her face and blood on the sleeve of her coat.