Reese almost had it all: a loving relationship with Amy, an apartment in New York City, a job she didn't hate. She had scraped together what previous generations of trans women could only dream of: a life of mundane, bourgeois comforts. The only thing missing was a child. But then her girlfriend, Amy, detransitioned and became Ames, and everything fell apart. Now Reese is caught in a self-destructive pattern: avoiding her loneliness by sleeping with married men.

Gilda, a 20-something, atheist, animal-loving lesbian, cannot stop ruminating about death. Desperate for relief from her panicky mind and alienated from her repressive family, she responds to a flyer for free therapy at a local Catholic church, and finds herself being greeted by Father Jeff, who assumes she’s there for a job interview. Too embarrassed to correct him, Gilda is abruptly hired to replace the recently deceased receptionist Grace.

Leah is changed. Months earlier, she left for a routine expedition, only this time her submarine sank to the sea floor. When she finally surfaces and returns home, her wife Miri knows that something is wrong. Barely eating and lost in her thoughts, Leah rotates between rooms in their apartment, running the taps morning and night. As Miri searches for answers, desperate to understand what happened below the water, she must face the possibility that the woman she loves is slipping from her grasp.

Blythe Connor is determined that she will be the warm, comforting mother to her new baby Violet that she herself never had. But in the thick of motherhood's exhausting early days, Blythe becomes convinced that something is wrong with her daughter - she doesn't behave like most children do. Or is it all in Blythe's head? Her husband, Fox, says she's imagining things. The more Fox dismisses her fears, the more Blythe begins to question her own sanity, and the more we begin to question what Blythe is telling us about her life as well.

Big Burr, Kansas is the kind of place where everyone seems to know everyone - or so they think. But when a national nonprofit labels Big Burr “the most homophobic town in the US” and sends in a queer task force to live and work there for two years, no one is prepared for what will ensue.

Leslie Flores has the perfect life - a loving husband, a happy newborn, and a New Mexico home straight out of a magazine. She’s been the perfect daughter, too, taking care of her ailing father in his final days. But Leslie has a dark secret - and it’s an expensive secret to keep. When she discovers she won’t receive a penny of her inheritance unless she finds her estranged sister, Robin, she sets out to track her down. Instead, upon arriving at Robin’s apartment, Leslie discovers her body.

When Sara Foster runs away from home at 16, she leaves behind not only the losses that have shattered her world but the girl she once was, capable of trust and intimacy. Years later, in Los Angeles, she is a sought-after bartender, renowned as much for her brilliant cocktails as for the mystery that clings to her. Across the city, Emilie Dubois is in a holding pattern. In her sixth year and fifth major as an undergraduate, she yearns for the beauty and community her Creole grandparents cultivated but is unable to commit.

In Shaker Heights, a placid, progressive suburb of Cleveland, everything is planned - from the layout of the winding roads to the colors of the houses to the successful lives its residents will go on to lead. And no one embodies this spirit more than Elena Richardson, whose guiding principle is playing by the rules. Enter Mia Warren - an enigmatic artist and single mother - who arrives in this idyllic bubble with her teenage daughter, Pearl, and rents a house from the Richardsons.

Lily hasn’t always had it easy, but that’s never stopped her from working hard for the life she wants. She’s come a long way from the small town where she grew up—she graduated from college, moved to Boston, and started her own business. And when she feels a spark with a gorgeous neurosurgeon named Ryle Kincaid, everything in Lily’s life seems too good to be true.

Aging and reclusive Hollywood movie icon Evelyn Hugo is finally ready to tell the truth about her glamorous and scandalous life. But when she chooses unknown magazine reporter Monique Grant for the job, no one in the journalism community is more astounded than Monique herself. Why her? Why now? Monique is not exactly on top of the world. Her husband, David, has left her, and her career has stagnated.

Diana O’Toole is perfectly on track. She will be married by thirty, done having kids by thirty-five, and move out to the New York City suburbs, all while climbing the professional ladder in the cutthroat art auction world. She’s an associate specialist at Sotheby’s now, but her boss has hinted at a promotion if she can close a deal with a high-profile client. She’s not engaged just yet, but she knows her boyfriend, Finn, a surgical resident, is about to propose on their romantic getaway to the Galápagos - days before her thirtieth birthday. Right on time.

Sixteen-year-old Yamilet Flores prefers to be known for her killer eyeliner, not for being one of the only Mexican kids at her new, mostly white, very rich Catholic school. But at least here no one knows she’s gay, and Yami intends to keep it that way.

In bawdy, moving prose, Rita Mae Brown tells the story of Molly Bolt, the adoptive daughter of a dirt-poor Southern couple who boldly forges her own path in America. With her startling beauty and crackling wit, Molly finds that women are drawn to her wherever she goes - and she refuses to apologize for loving them back.

Growing up in 1950s Detroit, they live in a perfect “Dick and Jane” house, where their roles in the family are clearly defined. Jo is the tomboy, the bookish rebel with a passion to make the world more fair; Bethie is the pretty, feminine good girl, a would-be star who enjoys the power her beauty confers and dreams of a traditional life. But the truth ends up looking different from what the girls imagined. Jo and Bethie survive traumas and tragedies.

Morgan Flowers just wants to hide. Raised by their neurodivergent father, Morgan has grown up haunted by the absence of their mysterious mother, Zoe, especially now, as they navigate their gender identity and the turmoil of first love. Their father, Julian, has raised Morgan with care, but he can’t quite fill the gap left by the dazzling and destructive Zoe, who fled to Europe on Morgan’s first birthday. And when Zoe is dumped by her girlfriend Brigid, she suddenly comes crashing back into Morgan and Julian’s lives.