In this episode (our 100th!) we talk to Dr Raffaele Sarnataro, a postdoctoral researcher in Gero Miesenböck's group at the Centre for Neural Circuits and Behaviour in Oxford University, who is investigating the neurobiological basis of sleep using fruit flies (Drosophila Melanogaster) as a model organism. Raffaele shares with us his latest research on a novel role for mitochondria, in a small specialised population of neurons in the fly brain, to regulate the need for sleep. He also dives into the classical theories of why we sleep, whether the purpose of sleep is universal and evolutionarily conserved, how metabolism is related to sleep across organisms, and how sleep is related to body versus brain. Listen to find out more about the often overlooked mystery of sleep.

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