In this episode of Idea Collider, we sit down with Susan Galbraith from AstraZeneca, a leading figure in oncology R&D. Susan shares her journey from medical training in Manchester and Cambridge to spearheading transformative cancer treatments at AstraZeneca. She discusses pivotal moments in her career, AstraZeneca's vision for eliminating cancer as a cause of death, the role of patient stories in motivating R&D efforts, and the integration of emerging technologies like AI and digital health tools.

With a focus on collaboration and continuous learning, Susan provides insights into how successful oncology drugs are developed and the importance of equitable representation in clinical trials. Stay tuned for an engaging conversation that highlights the future of personalized cancer therapies and the collaborative efforts driving innovations in oncology.

Chapter Summaries;

00:00 Introduction and Guest Welcome

00:27 Susan Galbraith's Career Journey

02:37 Defining Success in Oncology R&D

05:01 Early Phase Drug Development

07:09 Digital Health and Patient Experience

12:37 Global Collaboration and Innovation

15:05 AI and Future of Oncology

28:08 Diversity and Inclusion in Clinical Trials

33:46 Mentorship and Career Advice

37:45 Challenges and Future Outlook in Oncology

42:06 Closing Remarks and Call to Action

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Keep up with Susan Gabraith;

• LinkedIn: https://www.linkedin.com/in/susan-galbraith-584a195/?originalSubdomain=uk

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In this episode of IDEA Collider, we dive into the world of biotech innovation with John Maraganore, former CEO of Alnylam Pharmaceuticals. Recognized as a trailblazer, John transformed RNA interference from a scientific concept into a revolutionary class of medicines, leading the development of five life-changing drugs.

Join us as we explore John's journey from a first-generation American with Greek immigrant parents to a key figure in biomedicine. We'll discuss his education at the University of Chicago, his leadership role at Alnylam, drug delivery challenges for RNAi therapeutics, and the importance of strategic pharmaceutical alliances. John also shares his take on the current biotech environment, the impact of policy and regulation, and the promising future of genetic medicines and AI in drug discovery.

Chapter Summaries;

00:00 Introduction to John Maraganore: Biotech Trailblazer

01:11 John's Early Life and Education

03:09 Joining Alnylam and the RNAi Revolution

04:56 Challenges and Successes at Alnylam

06:47 Current Biotech Funding Environment

08:17 Global Competition and US Leadership in Biotech

10:25 The Importance of In-Person Collaboration

12:01 Overcoming Drug Delivery Hurdles

15:21 Maintaining an Entrepreneurial Spirit in Biotech

17:00 Balancing Science and Business in Decision Making

20:27 Strategic Partnerships in Biotech

23:36 The Role of Biotech in Global Challenges

26:25 Advocating for Policy Changes in Biotech

30:41 Mentoring the Next Generation of Biotech Leaders

32:35 Future Frontiers in Biotech Innovation

36:08 John's Vision for the Future of Biomedicine

37:18 Communicating Innovation and Leadership

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Keep up with John Maraganore;

• LinkedIn: https://www.linkedin.com/in/john-maraganore/

Follow Mike Rea On;

• Website: https://www.ideapharma.com/
• X: https://x.com/ideapharma
• LinkedIn: https://www.linkedin.com/in/bigidea/

Listen to more fantastic podcast episodes: https://podcast.ideapharma.com/