Episode 301 hosts Dr Eyal Kramer (Plastic Surgeon from Tel Aviv, Israel) & Dr Ellen Selkon (Cosmetic Physician from Auckland, New Zealand).

In our 'Masterclass Series' we host global experts to teach us about fillers, bio-stimulators, bio-remodellers, polynucleotides, exosomes and other products. (For toxin insights, check out our other mini-series, 'The Tox Talks')

In Chapter 4 we focus on a new product launched by IBSA called 'Profhilo Structura'. Our conversation covers the technical aspects of the product, the difference between Profhilo and Profhilo Structura, how Structura works on a cellular level, patient choice and suitability, injecting techniques and more.

00:00 Introduction

00:51 300th Episode Celebration and IA Competition Announcement

02:10 Special Guests Introduction

04:01 Innovations in Aesthetic Medicine

09:41 Understanding Bio Remodeling and Healing

14:57 How Profilo Works On A Cellular Level

22:53 The Difference Between Profilo and Profhilo Structura

32:00 Practical Application of Profhilo Structura and The Patient Consultation

45:06 Injection Techniques with Profhilo Structura

45:44 Identifying Saggers vs Sinkers

48:58 Patient Experience and Immediate Effects

51:23 Protocol and Treatment Frequency

56:29 Complications and Safety

01:07:53 Combining Treatments and Techniques

01:27:10 Final Thoughts and Future Ideas

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To celebrate our milestone 300th episode, we are honoured to re-host Dr Jean Carruthers (Opthalmologist from Toronto, Canada) & Dr Michael Kane (Plastic Surgeon from New York, USA).

This episode is divided into Part 1 and Part 2. Part 2 is available to listen to for FREE by signing up to our Patreon as a 'free member':

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We've been priviledged to have hosted both of our guests on the podcast previously (episodes 120 and 190) and these rank in the top five of our most listened to episodes ever.

These two legendary pioneers helped discover and evolve the science of botulinum toxin treatments and facial aesthetics as a speciality. Jean and Michael's experience is unparalleled having both worked on the advisory boards and research teams from every major pharma company over the past 40 years. So we go on a deep dive to learn where we've come from, where we're currently at and where we might be going in the world of aesthetics.

01:48 Celebrating 300 Episodes

03:18 Special Guests: Dr. Jean Caruthers and Michael Kane

03:01 The Origins and Development of Toxins

04:55 Exploring the Hall Strain and Toxin Subtypes

07:14 Early Experiments and Discoveries

07:15 Early Trials and Challenges

13:01 Pioneering Techniques and Complications

22:51 Long-Term Effects of Muscle Relaxation

23:45 Exploring Botulinum Toxin B

28:32 Training and Techniques for New Injectors

35:22 Consultation and Patient Interaction

44:22 Beyond Wrinkles: Emotional Wellness

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Episode 299 hosts Dr Darryl Reed (Biochemist & COO of Tissue Repair from Sydney, Australia) and Charlotte Meli (Registered Nurse and NSW Territory Manager of Tissue Repair from Sydney, Australia)

In this episode we learn about Tissue Repair and their unique product TR Pro +. This novel hydrogel product contains beta-glucans (a derivative from yeast) and has been clincically proven and is TGA-approved to help wound healing.

We find out who Tissue Repair are, the science behind TR Pro + and how this can be applied in aesthetic practices.

This podcast was supported by Tissue Repair

00:30 Introduction

00:42 Our Upcoming 300th Podcast and IA Competition

02:01 Introducing Tissue Repair and TR Pro +

02:23 Darryl Reed's Journey into Aesthetics

04:10 Charlotte Meli's Background and Role

05:18 The Origins and Development of TR Pro +

07:41 Understanding Beta Glucans and Their Benefits

16:19 TGA Approval and Market Expansion

18:01 Clinical Studies and Real-World Evidence

22:18 Versatility and Benefits of TR Pro +

22:50 Clinical Feedback and Usage

23:35 Post-Injectable Applications

24:33 Science Behind the Semi-Permeable Film

25:15 Contraindications and Safety

27:38 Anti-Itching and Inflammation Control

29:04 Scar Treatment and Healing

30:17 Product Availability and Pricing

37:13 Future Developments and Applications

41:13 Conclusions and Final Thoughts

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