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The Great Antidote

The Great Antidote

De: Juliette Sellgren
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Adam Smith said, "Science is the great antidote to the poison of enthusiasm and superstition." So join us for interviews with the leading experts on today's biggest issues to learn more about economics, policy, and much more.

© 2025 The Great Antidote
Ciencia Ciencia Política Ciencias Sociales Filosofía Política y Gobierno
Episodios
  • It’s Not Goodbye, It’s See You Later with Amy Willis
    May 23 2025

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    In this special episode of The Great Antidote, Amy Willis of Liberty Fund takes the mic to interview Juliette Sellgren, the voice behind the show. Together, they reflect on the evolution of the podcast—from its early days to the hundreds of guests it has featured—and how Juliette herself has grown in the process.

    They talk about what it means to foster curiosity, how Juliette approaches reading (and recommends you do, too), and what makes for a great question. They also discuss the future of the podcast, the future of Juliette, and how The Great Antidote continues to explore the ideas of liberty and flourishing through meaningful conversation.

    We explore questions like:

    • What have been the most surprising lessons from interviewing economists, philosophers, and thinkers about liberty?
    • How has Juliette’s own worldview changed since the podcast began?
    • What is her approach to reading—and how does it fuel her curiosity?
    • If she could have dinner with any past guest (or figure), who would it be?

    Juliette Sellgren is the creator and host of The Great Antidote, a podcast by Liberty Fund that explores the ideas, institutions, and people behind a free society. She’s a researcher, writer, and lover of questions whose work bridges classical liberal ideas and public conversation.

    Whether you're a longtime listener or just tuning in, this behind-the-scenes episode offers an honest, reflective look at the voice behind the mic—and what’s next.

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    34 m
  • The Limits of Liberty: Buchanan’s Case for Constitutional Rules with Edward Lopez
    May 16 2025

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    What happens when people stop trusting rules—and start rewriting them?

    In this episode, we are joined by economist Edward Lopez about the life and legacy of James M. Buchanan, the Nobel Prize-winning founder of public choice economics. We begin by unpacking Buchanan’s biography and intellectual roots: what shaped his worldview, who influenced his thinking, and why his work remains foundational to understanding government, rules, and freedom.

    From there, we dive into the rich ideas in The Limits of Liberty—a dense but powerful book in which Buchanan asks: How can free individuals live together without descending into chaos or coercion? Lopez shares with us Buchanan’s key questions, his analytical framework, and the underlying principles that guide his work—especially his emphasis on rules, consent, and the boundaries of state power.

    We explore questions like:

    • Who was James Buchanan, and why does his work matter today?
    • What makes Buchanan a “consummate Smithian” and a classical liberal?
    • What are the central ideas in The Limits of Liberty—and why are they still so relevant?
    • How does public choice theory reshape how we understand politics, institutions, and individual freedom?

    Edward Lopez is a professor of economics and the BB&T Distinguished Professor of Capitalism at Western Carolina University. He directs the Center for the Study of Free Enterprise and is the past president of the Public Choice Society. His work focuses on the intersection of law, economics, and political processes, especially in the tradition of public choice and constitutional political economy.

    If you’ve ever wondered what holds free societies together—or what happens when the rules start to break—this episode is for you.

    Want to explore more?

    • Intellectual Portrait Series: A Conversation with James Buchanan
    • Pierre Lemieux, Lessons and Challenges in The Limits of Liberty, at Econlib.
    • Randy Simmons on Public Choice, a Great Antidote podcast.
    • Sandra Peart on Ethical Quandaries and Politics Without Romance, a Great Antidote podcast.
    • Edward Lopez, Socialism from the Bottom Up: Where Lawson and Powell Meet Hayek and Buchanan, at Econlib.


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    48 m
  • Why Some States Succeed: Mobility, Markets, and the Freedom to Flourish with Justin Callais
    May 9 2025

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    What makes some states thrive while others trap people in place? And what does it really mean to be free to move, grow, and flourish?

    In this episode, I talk with economist Justin Callais about the deep connections between personal fulfillment, economic mobility, and institutional quality. We begin with the personal: why real change starts internally, and how self-mastery and agency are prerequisites for meaningful, external progress. Then, we zoom out to ask: what kinds of systems make it easier for people to rise?

    We explore questions like:

    • What is economic mobility—and what does it look like in practice?
    • Why is Utah the top-performing states on the Archbridge Institute’s Social Mobility Index, while Louisiana lags behind?
    • How do factors like governance quality, opportunity, and freedom of movement shape people's life outcomes?
    • What role do individuals, institutions, and state policies play in promoting (or restricting) upward mobility?

    Justin Callais is the chief economist at the Archbridge Institute. He studies development economics, polycentric governance, and the institutional roots of freedom and flourishing.

    If you’ve ever wondered why where you live matters—or what it takes to build a society where people can truly move up in life—this conversation is for you.


    Want to explore more?

    • James Heckman on Inequality and Economic Mobility, an EconTalk podcast
    • Raj Chetty on Economic Mobility, an EconTalk podcast
    • Arnold Kling, The Kids Are...Different, at Econlib
    • Kerianne Lawson on Equal Economic Freedoms, a Great Antidote podcast
    • Jeremy Horpedahl on the Real Cost of Thriving Index, a Great Antidote podcast

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    1 h y 3 m
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