History Medicine Science

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

In 1920, at the end of the last major pandemic, global life expectancy was just over 40 years. Today, in many parts of the world, human beings can expect to live more than 80 years. As a species, we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Not too long ago, there was no coming back from death. But now, with revolutionary medical advances, death has become just another serious complication. As a young medical student, Dr. David Casarett was inspired by the story of a two-year-old girl named Michelle Funk. Michelle fell into a creek and was underwater for over an hour. When she was found she wasn't breathing, and her pupils were fixed and dilated. That drowning should have been fatal. But after three hours of persistent work, a team of doctors and nurses was able to bring her back.

In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease

In 1995, a scandal erupted when the New York Times revealed that the Smithsonian possessed a century’s worth of nude “posture” photos of college students. In this riveting history, Beth Linker tells why these photos were only a small part of the incredible story of twentieth-century America’s largely forgotten posture panic—a decades-long episode in which it was widely accepted as scientific fact that Americans were suffering from an epidemic of bad posture, with potentially catastrophic health consequences.

Since its publication in 1932, Black Elk Speaks has moved countless readers to appreciate the American Indian world that it described. John Neihardt’s popular narrative addressed the youth and early adulthood of Black Elk, an Oglala Sioux religious elder. Michael F. Steltenkamp now provides the first full interpretive biography of Black Elk, distilling in one volume what is known of this American Indian wisdom keeper whose life has helped guide others. Nicholas Black Elk: Medicine Man, Missionary, Mystic shows that the holy-man was not the dispirited traditionalist commonly depicted in literature....

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.

Blood Runs Coal comes at a time of resurgent labor movements in the United States and the current administration's attempts to bolster the fossil-fuel industry. Brilliantly researched and compellingly written, it sheds light on the far-reaching effects of industrial and socioeconomic change that unfold across America to this day.

Sigmund Freud revolutionized the way in which we think about ourselves. From its beginnings as a theory of neurosis Freud developed psychoanalysis into a general psychology, which became widely accepted as the predominant mode of discussing personality and interpersonal relationships. Anthony Storr goes one step further and investigates the status of Freud's legacy today and the disputes that surround it.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

Every medical decision - whether to have chemotherapy, an X-ray, or surgery - is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the first blood transfusions 400 years ago to the hunt for a COVID-19 vaccine, risk has been essential to the discovery of new treatments. More importantly, understanding the risks is crucial to whether, as a society or as individuals, we accept them.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

Today, 90 percent of psychiatric beds are located in jails and prisons across the United States, institutions that confine disproportionate numbers of African Americans. After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.

Little more than 100 years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world's environments had all been conquered. Likewise, in the 20th century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremes, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer.

Feeling feverish, tired, or achy? Listening to Gina Kolata's engrossing account of the 1918 Influenza epidemic is sure to give you the chills. A gripping work of science writing, Flu addresses the prospects for a great epidemic recurring, and considers what can be done to prevent it.

In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.

The Panic Virus is a gripping scientific detective story about how grassroots radicals, snake-oil salesmen, and cynical journalists have perpetrated the biggest health-scare hoax of all time. It explores what happens when the media treats all viewpoints as equally valid, regardless of facts, from parents who are convinced that vaccines caused their children's autism to right-wing radicals who believe that climate change is a myth

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.