History Medicine Science

In the 16th century, when explorers travelled deep into the jungles of South America in search of gold and spices, they brought back many colourful tales of their adventures. None of these tales was more astonishing, or caused more concern, than that of the mystical properties of the substance with which the natives anointed their darts and arrows.

Government, industry, and the medical profession, however, have a mixed record when it comes to framing policies and generating knowledge to address drug use and misuse. In Strange Trips, Lucas Richert investigates the myths, meanings, and boundaries of recreational drugs, palliative care drugs, and pharmaceuticals as well as struggles over product innovation, consumer protection, and freedom of choice in the medical marketplace.

It’s hard today to remember how recently cancer was a silent killer, a dreaded disease about which people rarely spoke in public. In hospitals and doctors’ offices, conversations about malignancy were hushed and hope was limited. In this deeply researched book, Elaine Schattner reveals a sea change—from before 1900 to the present day—in how ordinary people talk about cancer. From Whispers to Shouts examines public perception of cancer through stories in newspapers and magazines, social media, and popular culture.

In 2006, the Wall Street pioneer and philanthropist Ray Chambers flicked through some holiday snapshots taken by a friend and remarked on the placid beauty of a group of sleeping Malawian children. "They're not sleeping," his friend told him. "They're in malarial comas. A few days later, they were all dead." This moment sparked Chambers' determination to coordinate an unprecedented, worldwide effort to eradicate a disease that has haunted humanity since before the advent of medicine.

We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from 16th-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places.

In the 1970s, a small group of leading psychiatrists met behind closed doors and literally rewrote the book on their profession. Revising and greatly expanding the Diagnostic and Statistical Manual of Mental Disorders (DSM for short), they turned what had been a thin, spiral-bound handbook into a hefty tome. Almost overnight the number of diagnoses exploded. The result was a windfall for the pharmaceutical industry and a massive conflict of interest for psychiatry at large.

Dr. Lange graduated from medical school in 1981, right as a new plague swept across the globe. His story became intertwined with the story of HIV. At once a physician, scientist, AIDS activist, and medical diplomat, Lange studied ways to battle HIV and prevent its spread from mother to child. Fighting the injustices of poverty, Lange advocated for better access to health care for the poor and the vulnerable. The Impatient Dr. Lange is the story of one man's struggle against a global pandemic - and the tragic attack that may have slowed down the search for a cure.

Doctors at War is a candid account of a trauma surgical team based, for a tour of duty, at a field hospital in Helmand, Afghanistan. Mark de Rond tells of the highs and lows of surgical life in hard-hitting detail, bringing to life a morally ambiguous world in which good people face impossible choices and in which routines designed to normalize experience have the unintended effect of highlighting war’s absurdity. With stories that are at once comical and tragic, de Rond captures the surreal experience of being a doctor at war.

In Change Is Possible, public health legend William H. Foege and five coauthors chronicle the failures and successes of global health through the modern age, including the massive impacts of colonialism, religious groups, philanthropies, politics, NGOs, and more. Foege, who has served in local, national, and international public health contexts is uniquely qualified to reflect on the history of global health. He and his Rollins School of Public Health coauthors explain why colonialism has been the greatest disaster for global health, whereas military medicine may have been its greatest asset.

When British-born Elizabeth Blackwell earned her medical degree in America in 1849, there was an international outcry. Few at the time would have disagreed with the actress Fanny Kemble's remark - "What, trust a woman doctor - never!"

In 2009, an influential panel of medical experts ignited a controversy when they recommended that most women should not begin routine mammograms to screen for breast cancer until the age of 50, reversing guidelines they had issued just seven years before when they recommended 40 as the optimal age to start getting mammograms. Many women’s groups, health care advocates, and individual women saw the guidelines as privileging financial considerations over women’s health and a setback to decades-long efforts to reduce the mortality rate of breast cancer.

Pain is the number one reason people schedule medical appointments. Yet many people do not receive adequate relief, especially for chronic pain. Pain: The Culture and Science of Pain describes the multiple factors that contribute to the ongoing problem of unrelieved pain. There are both cultural and scientific reasons. The book discusses how various cultures and religions throughout history have downplayed the importance of relieving pain. Such biases persist today.

Although Professor Stephen Westaby was born with the necessary coordination and manual dexterity, it was a head trauma sustained during university that gifted him the qualities of an exceptional heart surgeon: qualities that are frequently associated with psychopathy. His 35-year career has been characterised by fearlessness and ruthless ambition, leaving empathy at the hospital door as thousands of patients put their lives in his hands.

Winner of the IgNobel Prize in physics and the 2004 American Institute of Physics Science Writing Award, Len Fisher showed just how much fun science can be in his enthusiastically praised debut, How to Dunk a Doughnut. In this new work, he reveals that science sometimes takes a path through the ridiculous and the bizarre to discover that Nature often simply does not follow common sense.

Humankind has always wrestled with the existence of suffering. For two centuries, many American ministers, physicians, and scientists believed that an omnipotent and omniscient God created the world such that people might relieve suffering through ingenuity and learning. Others responded to the new worldview introduced by the scientific revolution as a threat to the divine order. In Imagining Progress, Kristin Johnson traces the history of Americans' evolving relationship with science and religion at "one of its most dramatic places"—the bedsides of dying children.

Blood carries life, yet the sight of it makes people faint. It is a life-saver, and can transmit deadly infections. It is medicine, and a commodity dearer than oil. Each of us has nine to 12 pints of it, yet many don’t know their own blood type. For all its ubiqutousness, menstruation is perhaps the single most demonized biological event. In Nine Pints, Rose George takes us from ancient practices of bloodletting to a cutting-edge trauma ward.

What is embryonic stem cell research? Why is it so controversial? What is its relationship to human cloning? Events are moving so fast and biotechnology seems so complicated that many of us don't have an informed opinion about issues that are remaking the human future before our very eyes.

We have entered what is called the "biological century" and a new biopolitics has emerged to address the implications for America's collective value system, our well-being, and ultimately, our future. The Body Politic is the first book to recognize and assess this new force in our political landscape - one that fuels today's culture wars and has motivated politicians of all stripes to reexamine their platforms.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

The story starts with the initial moments of COVID's appearance in Wuhan and ends with Joseph Biden's inauguration in an America ravaged by well over 400,000 deaths - a mortality already some 10 times worse than US combat deaths in the entire Vietnam War. This is an anguished, furious memorial to a year in which all of America's great strengths - its scientific knowledge, its great civic and intellectual institutions, its spirit of voluntarism and community - were brought low by political incompetence and cynicism on a scale for which there has been no precedent.