Human Genetic Engineering

In ‘Humans Are Doomed To Go Extinct’, an article in Scientific American published in November 2021, veteran Nature editor Dr Henry Gee predicted that Homo sapiens is on a rapid one-way ride to extinction. The article provoked media coverage and comment around the world. In The Decline and Fall of the Human Empire, Gee expands the themes of his much-discussed article to book length, charting both the rise as well as the fall of humans. Gee paints a picture of extinction within the next 10,000 years – and suggests ways that our exceptional species might avoid its fate.

Parents and parents-to-be are bombarded with information, from what to expect to what to do (and not to do) when it happens. But what they may not realize is that from the chemistry of pregnancy tests to the vacuum physics of breastfeeding, there is fascinating science at the heart of every aspect of creating and raising a new human.

Darwin considered humans one part of the web of life, not the apex of a natural hierarchy. Yet today many maintain that we are the most intelligent, virtuous, successful species that ever lived. This flawed thinking enables us to exploit the earth towards our own exclusive ends, throwing us into a perilous planetary imbalance. But is this view and way of life inevitable? The Arrogant Ape shows that human exceptionalism is an ideology that relies more on human culture than our biology, more on delusion and faith than on evidence.

After seeing his own cells used to grow clumps of new neurons - essentially mini-brains - Philip Ball begins to examine the concepts of identity and consciousness. Delving into humanity's deep evolutionary past to look at how complex creatures like us emerged from single-celled life, he offers a new perspective on how humans think about ourselves.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

In 1997, Yiannis Kouros ran 188 miles in 24 hours. In 1984, at age 42, Maria Moreira gave birth to her 10th set of twins. In 1973, Terry Tao learned to read when he was two years old. Tao started college at age nine, and at 24 was appointed a full-time professor at UCLA. What does it feel like to be exceptional? And what does it take to get there? Why can some people achieve greatness when others can’t, no matter how hard they try? Just how much potential does our species have? Evolutionary biologist Rowan Hooper has the answers.

AD 2107: A generation ago, Earth and the cislunar colonies banned genetic and cybernetic modifications. But out in the Asteroid Belt, anything goes. Dozens of flourishing space habitats are spawning exotic new societies and strange new varieties of humans. It’s a volatile situation that threatens the peace and stability of the entire solar system.

Pets have never been more popular. Over half of American households share their home with either a cat or a dog, and many contain both. This is a huge change from only a century ago, when the majority of domestic cats and dogs were working animals, keeping rodents at bay, guarding property, herding sheep. Nowadays, most are valued solely for the companionship they provide. As mankind becomes progressively more urban and detached from nature, we seem to be clinging to the animals that served us well in the past.

Lia Johansen was created for only one purpose: to slip onto the strategically placed New Sol Space Station and explode. But her mission goes to hell when her clock malfunctions, freezing her countdown with just two minutes to go. With no Plan B, no memories of her past, and no identity besides a name stolen from a dead POW, Lia has no idea what to do next. Her life gets even more complicated when she meets Michael Sorenson, the real Lia's childhood best friend.

Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25 percent of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals but not because we are evolutionary outliers.

In the spring of 2012, the Berkeley biochemist Jennifer Doudna and her collaborators turned a curiosity of nature into an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020, and make inheritable changes in the genes of babies.

In Eve, Cat Bohannon answers questions scientists should have been addressing for decades. With boundless curiosity and sharp wit, she covers the past 200 million years to explain the specific science behind the development of the female sex. Eve is not only a sweeping revision of human history, it’s an urgent and necessary corrective for a world that has focused primarily on the male body for far too long.

We like to think of ourselves as exceptional beings, but are we really any more special than other animals? Humans are the slightest of twigs on a single family tree that encompasses four billion years, a lot of twists and turns and a billion species. All of those organisms are rooted in a single origin, with a common code that underwrites our existence. This paradox - that our biology is indistinct from all life, yet we consider ourselves to be special - lies at the heart of who we are.

In this engaging exploration, archaeologist Ian Hodder departs from the two prevailing modes of thought about human evolution: the older idea of constant advancement toward a civilized ideal and the newer one of a directionless process of natural selection. Instead, he proposes a theory of human evolution and history based on "entanglement," the ever-increasing mutual dependency between humans and things.

In this intriguing book, evolutionary biologist Scott Solomon draws on the explosion of discoveries in recent years to examine the future evolution of our species. Combining knowledge of our past with current trends, Solomon offers convincing evidence that evolutionary forces still affect us today. But how will modernization - including longer lifespans, changing diets, global travel, and widespread use of medicine and contraceptives - affect our evolutionary future?

In Unfit for Purpose, biologist and broadcaster Adam Hart explores the mismatch between our fundamental biology and the modern world we have created. In each chapter Adam reveals the many ways in which biological adaptations that evolved to help us survive and thrive now work against us. For example, in the modern world stress is a killer, but how did 'fight or flight' instincts turn from life-savers to life-takers? Obesity might be a disease now, but is it really just a troublesome side-effect of our complex evolutionary past?

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

The year is 2205. The great pandemic and climate crisis generated social divisions, creating a new human post-biological species when a mining incident was manipulated to create the conditions of a new evolutionary social brink. This book is the first in a series about one potential path humanity may take in the evolution of new human species. There are exciting times ahead in this book. There are also bumps in the road and challenging events to navigate through. Listening to this audiobook will take you on a journey of different experiences that no one else has ever had.

Few of us know much about the biology of sex determination, but what could be more interesting than to discover how we are shaped into males and females? In this book, Elof Carlson tells the incredible story of the difficult quest to understand how the body forms girls and boys. Carlson's history takes us from antiquity to the present day to detail how each component of human reproduction and sexuality was identified and studied....

Fifty thousand years ago, we were not the only species of human in the world. There were at least four others, including the Neanderthals, Homo floresiensis, Homo luzonesis and the Denisovans. At the forefront of the latter's ground-breaking discovery was Oxford Professor Tom Higham. In The World Before Us, he explains the scientific and technological advancements.