Industrial Engineering

In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease

The kidney is an extraordinary organ—in many ways the regulator, the metronome, the keeper of the human body’s delicate equilibrium. On a given day, minute by minute, it purifies the body of toxins it encounters from diet, climate, activity, and injury. It allows us to be and to move in the world. And yet most of us know so very little about these extraordinary vessels nestled in our bodies—and indeed millions of us only really learn about them when they stop working. Nearly a million Americans every year have end stage kidney disease, about 37 million have some form of chronic kidney disease.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

Most stories of medical progress come with ready-made heroes. John Snow traced the origins of London's 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence Nightingale's contributions to the care of soldiers in the Crimean War transformed hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Little more than 100 years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world's environments had all been conquered. Likewise, in the 20th century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremes, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer.

In 2004, an enigmatic charter captain named Al Anderson caught and marked one Atlantic bluefin tuna off New England’s coast with a plastic fish tag. Fourteen years later that fish—dubbed Amelia for her ocean-spanning journeys—died in a Mediterranean fish trap, sparking Karen Pinchin’s riveting investigation into the marvels, struggles, and prehistoric legacy of this remarkable species.

They didn't start out as environmental warriors. Clair Patterson was a geochemist focused on determining the age of the Earth. Herbert Needleman was a pediatrician treating inner-city children. But in the chemistry lab and the hospital ward, they met a common enemy: lead. It was literally everywhere. Though few people worried about it at the time, lead was also toxic. In Toxic Truth, journalist Lydia Denworth tells the little-known stories of these two men who were among the first to question the wisdom of filling the world with such a harmful metal.

From St. Louis to New Orleans, from Baltimore to Oklahoma City, there are poor and minority neighborhoods so beset by pollution that just living in them can be hazardous to your health. Due to entrenched segregation, zoning ordinances that privilege wealthier communities, or because businesses have found the "paths of least resistance", there are many hazardous waste and toxic facilities in these communities, leading residents to experience health and wellness problems on top of the race and class discrimination most already experience.

Here, for the first time, is a collection of short speeches by the charismatic doctor and social activist Paul Farmer. One of the most passionate and influential voices for global health equity and social justice, Farmer encourages young people to tackle the greatest challenges of our times. Engaging, often humorous, and always inspiring, these speeches bring to light the brilliance and force of Farmer's vision in a single, accessible volume.

Award-winning author William Rosen tells the story of the men responsible for the Industrial Revolution and the machine that drove it: the steam engine.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

New York Times best-selling author Seth Siegel tells how contaminants got in our drinking water, what they’re doing to us, and what we must do to make our water safe.

Fashion is political. From the red carpets of the Met Gala to online fast fashion, clothes tell a story of inequality, racism and climate crisis. In The Anti-Capitalist Book of Fashion, Tansy E. Hoskins unpicks the threads of capitalist industry to reveal the truth about our clothes.

In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, each joined the Resistance to help liberate the country from the Nazis and ascended to prominent, dangerous roles. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in their respective fields.

When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.

This humbling and revelatory book shows how infectious disease has shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam. How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are.