Industrial Engineering

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

Take a tour with the author inside more than 30 world-class facilities to experience the most remarkable innovations and highly sophisticated robotics and automation in action. Capture a front-row seat to top-brand, big-budget manufacturing in action with complex machines communicating with other machines. However, you can also learn from small-to-medium size manufacturers. Discover how some simple, tried-and-true, old-school, low-budget manufacturing processes can be game changers for industry.

Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them.

From our offices and homes to schools, hospitals, and restaurants, the indoor spaces where we work, learn, play, eat, and heal have an outsized impact on our performance and well-being. They affect our creativity, focus, and problem-solving ability and can make us sick - jeopardizing our future and dragging down profits in the process. Joseph Allen and John Macomber make a compelling case in this urgently needed book for why every business and home owner should make certain relatively low-cost investments a top priority.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In 1900, the U.S. sent three doctors to Cuba to discover how yellow fever was spread. There, they launched one of history's most controversial human studies. Compelling and terrifying, The American Plague depicts the story of yellow fever and its reign in this country - and in Africa, where even today it strikes thousands every year. With "arresting tales of heroism," it is a story as much about the nature of human beings as it is about the nature of disease.

Here is the inspiring story of how Dr. Mona Hanna-Attisha, alongside a team of researchers, parents, friends, and community leaders, discovered that the children of Flint, Michigan, were being exposed to lead in their tap water - and then battled her own government and a brutal backlash to expose that truth to the world. Paced like a scientific thriller, What the Eyes Don’t See reveals how misguided austerity policies, broken democracy, and callous bureaucratic indifference placed an entire city at risk.

More than 80,000 new chemicals have been developed and released into the global environment during the last four decades. Today the World Health Organization attributes more than one-third of all childhood deaths to environmental causes, and as rates of childhood disease skyrocket, it raises serious, difficult questions around how the chemical environment is impacting children's health. Children and Environmental Toxins: What Everyone Needs to Know® offers an accessible guide to understanding and identifying the potential sources of harm in a child's environment.

K. Eric Drexler is the founding father of nanotechnology - the science of engineering on a molecular level. In Radical Abundance, he shows how rapid scientific progress is about to change our world. Thanks to atomically precise manufacturing, we will soon have the power to produce radically more of what people want, and at a lower cost. The result will shake the very foundations of our economy and environment.

From mechanical looms to the combustion engine to the first computers, new technologies have always provoked panic about workers being replaced by machines. For centuries, such fears have been misplaced, and many economists maintain that they remain so today. But as Daniel Susskind demonstrates, this time really is different. Breakthroughs in artificial intelligence mean that all kinds of jobs are increasingly at risk.

By 1979, we knew nearly everything we understand today about climate change—including how to stop it. Over the next decade, a handful of scientists, politicians, and strategists, led by two unlikely heroes, risked their careers in a desperate, escalating campaign to convince the world to act before it was too late. Losing Earth is their story, and ours.

Far more than a rhetorical exercise, this book is designed to inform, inspire, and spur action. Based on Sachs' 14 years as director of the Earth Institute at Columbia University and as special advisor to the United Nations Secretary-General on the Millennium Development Goals and Sustainable Development Goals, The Age of Sustainable Development is a landmark publication and a clarion call for all who care about our planet and global justice.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

Did you ever want to start 3D printing but think it might be too difficult to learn? Do you feel that the subject matter is overly technical and possibly out of reach? Or do you believe that it would be just too complicated to even get started? We know the struggle very well and understand how you feel. In this book, we will help you to overcome all of these obstacles and more. Not only do we offer a brief history of how 3D printing came to be, we will help guide all prospective hobbyist on how to get started from scratch.

There is a major disconnect between what we wear and our knowledge of its impact on land, air, water, labor, and human health. Even those who value access to safe, local, nutritious food have largely overlooked the production of fiber, dyes, and the chemistry that forms the backbone of modern textile production. While humans are 100 percent reliant on their second skin, it’s common to think little about the biological and human cultural context from which our clothing derives.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.