Medical History

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

The life and medical practice of Reuben Harris Muth, M.D., a rural saddlebag doctor, is reconstructed from an extant set of physician’s daybooks, chronicling his professional activity from 1858 until 1898, including patients seen and the fees charged. The daybooks also provided a modicum of hints at other activities in his life, including his farming business and the whereabouts of his wayward son. However, there were no personal letters or diaries available. Thus, other primary sources and local newspaper accounts were utilized to fill out the most likely details and actions of his life,...

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Nearly two decades after it closed, the South Carolina State Hospital continues to hold a palpable mystique in Columbia and throughout the state. Founded in 1821 as the South Carolina Lunatic Asylum, it housed, fed, and treated thousands of patients incapable of surviving on their own. The patient population in 1961 eclipsed 6,600, well above its listed capacity of 4,823. By the mid-1990s, the patient population had fallen under 700, and the hospital had become a symbol of captivity, horror, and chaos.

Army combat veteran and registered nurse Erin Olszewski's most deeply held values were put to the test when she arrived as a travel nurse at Elmhurst Hospital in the epicenter of the COVID-19 pandemic. After serving in Iraq, she was back on the front lines - and this time, she found, the situation was even worse. Rooms were filthy, nurses were lax with sanitation measures, and hospital-acquired cases of COVID-19 were spreading like wildfire.

Who is stealing dead bodies … and why? Emma Carter is struggling to follow her dream. A simple country girl from Georgia, she is learning to live and study in the bustling 1890s city of Philadelphia, Pennsylvania. But women medical students like Emma face many challenges and obstacles unknown to their male counterparts. Will people ever accept a female doctor? As a sexton, Michael Sheppard’s duties include assisting with burials and maintaining Saint Mark’s church and cemetery. When grave robbers disrupt the peaceful slumber of the deceased and sell them to area medical schools for ...

After his father died, James L. Nolan, Jr., took possession of a box of private family materials. To his surprise, the small secret archive contained a treasure trove of information about his grandfather's role as a doctor in the Manhattan Project. Dr. Nolan, it turned out, had been a significant figure.

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.

As scientists confidently look forward to average life expectancies hitting 100+ years in some Western societies, it’s easy to forget how precarious our grasp on good health has been. It is a struggle no better demonstrated than by the myriad and extraordinary measures that humans have gone to – as diverse as animal sacrifice to stem cell transplants – in their quest to stave off death and disease. Acclaimed historian Mark Jackson takes a fresh global view of mankind’s great battle, exploring both Western and Eastern traditions.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

What do dinosaurs, a Neanderthal elder named Nandy, Ötzi-the Ice Mummy, Chinese Chickens, Roman Cats, Richard the Lionhearted, and Catherine of Aragon have in common? The answer: they all suffered from Lyme disease or related Tick-borne infections. Lyme disease is caused by a group of bacteria called Borrelia that have been around for millions of years. It is a spiral shaped spirochete that is spread by the bite of Ixodes ticks. Lyme disease is recognized by the CDC as the leading cause of tick-borne infection in the United States. The history of this spiral is one of persistence. ...

From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed. The First World War claimed millions of lives and left millions more wounded and disfigured. In the midst of this brutality, however, there were also those who strove to alleviate suffering. The Facemaker tells the extraordinary story of such an individual: the pioneering plastic surgeon Harold Gillies.

Caroline Crampton’s life was upended at the age of seventeen, when she was diagnosed with Hodgkin’s lymphoma, a relatively rare blood cancer. After years of invasive treatment, she was finally given the all clear. But being cured of the cancer didn’t mean she felt well. Instead, the fear lingered, and she found herself always on the alert, braced for signs that the illness had reemerged.

Heroines of Mercy Street tells the true stories of the nurses at Mansion House, the Alexandria, Virginia, mansion turned wartime hospital and setting for the new PBS drama Mercy Street. Among the Union soldiers, doctors, wounded men from both sides, freed slaves, politicians, speculators, and spies who passed through the hospital in the crossroads of the Civil War were nurses who gave their time freely and willingly to save lives and aid the wounded.

Patti Davis, the daughter of Ronald and Nancy Reagan, writes about losing her father to Alzheimer's disease, saying goodbye in stages, and watching the progression of a disease that steals what is most precious: a person's memory. Past and present come together in this illuminating portrait of grief, of a man, a disease, and a girl and her father.

Dr. John Sullivan is the medical director of the Philadelphia General Hospital’s Alzheimer’s unit. He’s also a member of the West Philadelphia Historical Society, spearheading an effort to document as much information as possible regarding the hospital’s Franklin Wing, an abandoned section of the medical complex set to be razed. During his research, Dr. Sullivan acquaints himself with Dr. Zachary Schmidt, an eccentric and at times controversial physician who worked in the Franklin Wing until his mysterious disappearance on July 4th, 1976. There, in Dr. Schmidt’s former office, ...

Long before the U.S. government began conducting secret radiation and germ-warfare experiments, and long before the Tuskegee syphilis experiments, medical professionals had introduced—and hotly debated the ethics of—the use of human subjects in medical experiments. In Subjected to Science, Susan Lederer provides the first full-length history of biomedical research with human subjects in the earlier period, from 1890 to 1940.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.