On a warm summer morning in North Carthage, Missouri, it is Nick and Amy Dunne’s fifth wedding anniversary. Presents are being wrapped and reservations are being made when Nick’s clever and beautiful wife disappears. Husband-of-the-Year Nick isn’t doing himself any favors with cringe-worthy daydreams about the slope and shape of his wife’s head, but passages from Amy's diary reveal the alpha-girl perfectionist could have put anyone dangerously on edge.

A girl with a secret. Longbill Beach, 1982. Emily Vaughn gets ready for the prom. For an athlete, who is smart, pretty and well-liked, this night that should be the highlight of her high school career. But Emily has a secret. And by the end of the evening, that secret will be silenced forever. Forty years later, Emily’s murder remains a mystery. Her tight-knit group of friends closed ranks; her respected, wealthy family retreated inwards; the small town moved on from her grisly attack. But all that’s about to change.

Marc Seidman awakens to find himself in an ICU, hooked up to an IV, his head swathed in bandages. Twelve days earlier, he had had an enviable life as a successful surgeon, living in a peaceful suburban neighborhood with his beautiful wife and a baby he adored. Now he lies in a hospital bed, shot by an unseen assailant. His wife has been killed, and his 6-month-old daughter, Tara, has vanished. But just when his world seems forever shattered, something arrives to give Marc a new hope: a ransom note.

Tia and Mike Baye never imagined they'd become the type of overprotective parents who spy on their kids. But their 16-year-old son, Adam, has been unusually distant lately, and after the suicide of his classmate, Spencer Hill they can't help but worry. They install a sophisticated spy program on Adam's computer, and within days they are jolted by a message from an unknown correspondent addressed to their son: "Just stay quiet and all safe."

Meanwhile, Betsy Hill is struck by a photo that appears to have been taken on the night of her son's death...and he wasn't alone.

In 1985, Yale Tishman, the development director for an art gallery in Chicago, is about to pull off an amazing coup, bringing in an extraordinary collection of 1920s paintings as a gift to the gallery. Yet as his career begins to flourish, the carnage of the AIDS epidemic grows around him. One by one, his friends are dying and after his friend Nico's funeral, the virus circles closer and closer to Yale himself. Soon the only person he has left is Fiona, Nico's little sister.

Everyone in the quiet Jersey Shore town of Silver Bay knows the story: on a Sunday evening in September 1991, Ramsey Miller threw a blowout block party, then murdered his beautiful wife and three-year-old daughter. But everyone is wrong. The daughter got away. Now she is nearly eighteen and tired of living in secrecy. Under the name Melanie Denison, she has spent the last fifteen years in small-town West Virginia as part of the Witness Protection Program. She has never been allowed to travel, go to a school dance, or even have internet at home. Precautions must be taken at every turn, because Ramsey Miller was never caught and might still be looking for his daughter.

Teddy Telemachus is a charming con man with a gift for sleight of hand and some shady underground associates. In need of cash, he tricks his way into a classified government study about telekinesis and its possible role in intelligence gathering. There he meets Maureen McKinnon, and it's not just her piercing blue eyes that leave Teddy forever charmed but her mind - Maureen is a genuine psychic of immense and mysterious power.

Sports agent Myron Bolitar is poised on the edge of the big-time. So is Christian Steele, a rookie quarterback and Myron's prized client. But when Christian gets a phone call from a former girlfriend, a woman who everyone, including the police, believes is dead, the deal starts to go sour. Suddenly Myron is plunged into a baffling mystery of sex and blackmail.

Former homicide detective Nicole Foster has hit rock bottom. Driven off the force by her treacherous partner and lover, she's flat broke and struggling with a gambling addiction. All Nicole has left is the dream of a warm bed at a homeless shelter and the haunting memories of three-year-old Kelsey Chase—whose murder case ended her career. As Nicole obsesses over the old facts, she realizes everything about that case felt off.

After 27 years of marriage and three children, Anna Oh - wife, mother, outsider artist - has fallen in love with Viveca, the wealthy Manhattan art dealer who orchestrated her success. They plan to wed in the Oh family’s hometown of Three Rivers in Connecticut. But the wedding provokes some very mixed reactions and opens a Pandora’s Box of toxic secrets - dark and painful truths that have festered below the surface of the Ohs' lives.

Competitive skier Mindy Wright is a superstar in the making until a spectacular downhill crash threatens not just her racing career but her life. During surgery, doctors discover she’s suffering from a severe form of leukemia, and a stem cell transplant is her only hope. But when her parents are tested, a frightening truth emerges. Mindy is not their daughter.

From marriage, infidelity, and the mayhem of motherhood to scandal, tragedy, and illness - three women seek peace and comfort in Nantucket as they cope with life's challenges. Three women - burdened with small children, unwieldy straw hats, and some obvious emotional issues - tumble onto the Nantucket airport tarmac one hot June day. Vicki is trying to sort through the news that she has a serious illness. Her sister, Brenda, has just left her job after being caught in an affair with a student. And their friend Melanie, after seven failed in vitro attempts, is pregnant at last.

On an icy winter's day in southwest Michigan, Grace Abbot wakes up as the survivor of a car crash. But she's left with a traumatic brain injury and a terrifying reality: she can't remember anything. Left in the care of her sister, Grace returns to the family's secluded old farmhouse to recover - but within an hour of her return, the police arrive. Grace's boyfriend has been murdered. Without any memory, Grace has no alibi.

At the end of a long winter in well-to-do Ridgedale, New Jersey, the body of an infant is discovered in the woods near the town's prestigious university campus. No one knows who the baby is or how her body ended up out there. But there is no shortage of opinions.

Dear Anna, What I have to tell you is difficult to write, but I know it will be far more difficult for you to hear, and I'm so sorry. The unfinished letter is the only clue Tara and Emerson have to the reason behind their close friend Noelle's suicide. Everything they knew about Noelle - her calling as a midwife, her passion for causes, her love for her friends and family - described a woman who embraced life. Yet there was so much they didn't know. With the discovery of the letter and its heartbreaking secret, Noelle's friends begin to uncover the truth about this complex woman who touched each of their lives.