Doctor Jack Wright runs the Venom Lab, keeping mambas, cobras, and vipers of all kinds. He risks his life daily, extracting toxins directly from the fangs of the most venomous serpents in the world. But after a break-in at the lab, dozens of these deadly reptiles have escaped into the surrounding neighborhoods.

The piranha–razor-toothed terror of the Amazon–attacking in swarms, stripping flesh off the bones of helpless victims in seconds. Piranha have never been successfully introduced into American waters...until now.

Like shadows in the night, Captain Andrew Serrano and his elite team intercept the cargo ship Griffin, secretly owned by a Russian arms dealer. Their objective: capture the bio-engineer Dr. Hank Nore and deliver him to the C.I.A. The operation initially goes well, with the team overpowering the security forces and tracking their target to the lower decks. Backed into a corner, Dr. Nore resorts to desperate measures to avoid capture.

It was supposed to be a simple mission. A suspected Russian spy boat is in trouble in Canadian waters. Investigate and report are the orders. But when Captain John Banks and his squad arrive, it is to find an empty vessel, and a scene of bloody mayhem. Soon they are in a fight for their lives, for there are things in the icy seas off Baffin Island, scuttling, hungry things with a taste for human flesh. They are swarming. And they are growing.

Sixty-five million years ago... An artificial alien intelligence has come to strip-mine the prehistoric Earth but when their robotic automations kill a mother T. rex, they start a war. One of her hatchlings has survived, traveling with an adoptive raptor pack and as the orphaned tyrannosaur grows, they wage a guerrilla war against an invading army of war-bots and giant cloned-cyborgs.