1918, London. Twenty-year-old Emily Burdon has been training as a nurse at St. Marylebone Infirmary, learning on the job as she tends to patients from the crowded poorhouses that ring the hospital as well as wounded soldiers returning from the war. She pours her heart into her nursing while she waits for happier times - peace in Europe and the return of her childhood sweetheart, Lewis, from the Western Front. But when the deadly Spanish Flu arrives in London on the heels of the war, Emily’s faith and courage are put to the test.

Liverpool, 1855. Ada Houston is alone. Her grandfather has recently passed away, and her brother is missing, last seen working on the Liverpool docks. Everyone assumes him to be dead. But she will not give up hope. Ada's determined search takes her to the Crimea, where she joins the team of Florence Nightingale's nurses. She may have set off looking for her brother, but along the way Ada finds friends, romance and a new purpose in her own life in the most troubling and difficult of places.

Ana Kaminski is pushed through the iron gates of Auschwitz beside her frightened young friend Ester Pasternak. As they reach the front of the line, Ana steps forward and quietly declares herself a midwife--and Ester her assistant. Their arms are tattooed and they’re ordered to the maternity hut. Holding an innocent newborn baby, Ana knows the fate of so many are in her hands and vows to do everything she can to save them.

In Nazi-occupied Poland, Sofia cannot look her father in the eye. Sofia’s mother, her papa’s cherished wife, is Jewish—how dare he work as a doctor for the SS? She cannot forgive him, even if the bargain was made to spare their lives. In the middle of the night, Isaac emerges from a packed train with hundreds of others. Beneath Auschwitz’s barbed wire, the SS decide prisoners’ fates on the spot—and Isaac is chosen to work. Every breath feels like it could be Isaac’s last, so when he sees a beautiful auburn-haired girl peering out of the farm window, it feels like a dream.

Germany, 1939. A tumbledown farmhouse, on the outskirts of a close-knit village in the heart of the rolling hills of Bavaria. A once happy family home torn apart by Nazi rule. And one young girl who refuses to give up on what she believes in...London, 2018: When 94-year-old Imogen receives a letter addressed to her in neat, unfamiliar handwriting, she notices the postmark is stamped from Germany - and it sends shivers down her spine....

1938, Salzburg. Johanna, Birgit, and Lotte Eder have always lived quiet lives, working in their father’s clockmaking shop and helping their mother in the house. But like many other Austrians, they find it impossible to ignore the changes in the world around them. At first Johanna finds it hard to believe the Nazis pose a real threat. But then her father hires Franz to help in his shop. He’s kind and soulful, with dark eyes that twinkle with intelligence. But he’s Jewish, and as Johanna falls for him, she realizes that loving him puts them all in danger.

When Eleanor Atherton graduates from medical school near the top of her class in 1917, she dreams of going overseas to help the wounded, but her ambition is thwarted at every turn. Eleanor's parents insist she must give up medicine, marry a respectable man, and assume her proper place. While women might serve as ambulance drivers or nurses at the front, they cannot be physicians - that work is too dangerous and frightening. Nevertheless, Eleanor is determined to make more of a contribution than sitting at home knitting for the troops.

1938: Magda has led a sheltered life in her small village until the day she is forced from her home by the invading Nazi army. Torn away from her family and the only place she has ever known, she is offered refuge in an alpine villa owned by brilliant Dr, Tauber and his talented, beautiful wife. But despite having friends in high places, the Jewish Taubers are living on borrowed time. When the Gestapo come to arrest them, Magda is asked to protect something more precious than the silver and jewels they leave behind. Their newborn son Samuel.

London, 1941. The Blitz. When a Royal Navy memo arrives at head office, requesting female recruits to sign up as motorcycle dispatch riders, delivering highly classified orders across the country, three women jump at the chance to sign up for the most dangerous jobs in London.

Sicily, 1943. Three American women, all nurses in the Medical Air Evacuation Transport Squadron, are determined to do all they can for their country. Vita is fun-loving, Dot shy and sweet-natured, and Evelyn practical and determined, but for all their differences, a life of military service pulls the three together as firm friends. When they’re selected for a daring mission, the women are proud to play their part. But disaster strikes when their plane crash-lands behind enemy lines in occupied Albania. finally find their way home?

London, 1940. Britain is gripped by the terror of the Blitz, forcing Nell Spelman to flee the capital with her young daughter - leaving behind her husband, Arthur, the clockmaker who keeps Big Ben chiming. When Arthur disappears, Nell is desperate to find him. But her search will lead her into far darker places than she ever imagined.

Billeted together in the attic of Latimer House—a place where secrets abound—Evelyn, Betty and Judith soon form a bond of friendship that carries them through the war. Because nothing is stronger than women united. Tucked away in the Buckinghamshire countryside, Latimer House, a grand country estate, stands proudly—a witness to some of greatest secrets of WW2.

Occupied Poland, 1942: Despite the constant presence of German soldiers in her village, Emilia is allowed certain freedoms as a midwife—the most precious is innocently cycling past Nazi checkpoints to the homes of expectant mothers on her rounds. But Emilia has a secret: for years she’s also been visiting the hidden Jewish mothers and working for the resistance…until she is betrayed.

In an Ireland doubly ravaged by war and disease, Nurse Julia Power works at an understaffed hospital in the city center, where expectant mothers who have come down with the terrible new flu are quarantined together. Into Julia's regimented world step two outsiders - Doctor Kathleen Lynn, a rumored Rebel on the run from the police, and a young volunteer helper, Bridie Sweeney. In the darkness and intensity of this tiny ward, over three days, these women change each other's lives in unexpected ways.

At the heart of Dover's Market Square lies the Castle's Café. A bustling, homely place run by the formidable Nellie Castle and her six children. Since the scandalous birth of her beloved son 10 years before, Marianne, Nellie's eldest daughter, has preferred to stay in the kitchen, hidden away from the town gossips. Overcome with shame, Marianne has never revealed the name of Donny's father - not even to her own mother. But with World War II just around the corner, Marianne's past catches up with her. And suddenly the lives of the Castle family become a lot more complicated.