On the world called Hyperion, beyond the law of the Hegemony of Man, there waits the creature called the Shrike. There are those who worship it. There are those who fear it. And there are those who have vowed to destroy it. In the Valley of the Time Tombs, where huge, brooding structures move backward through time, the Shrike waits for them all.

Cloud Atlas begins in 1850 with Adam Ewing, an American notary voyaging from the Chatham Isles to his home in California. Along the way, Ewing is befriended by a physician, Dr. Goose, who begins to treat him for a rare species of brain parasite.... Abruptly, the action jumps to Belgium in 1931, where Robert Frobisher, a disinherited bisexual composer, contrives his way into the household of an infirm maestro who has a beguiling wife and a nubile daughter....

The story begins in 1962. On a rocky patch of the sun-drenched Italian coastline, a young innkeeper, chest-deep in daydreams, looks out over the incandescent waters of the Ligurian Sea and spies an apparition: a tall, thin woman, a vision in white, approaching him on a boat. She is an actress, he soon learns, an American starlet, and she is dying. And the story begins again today, half a world away, when an elderly Italian man shows up on a movie studio's back lot - searching for the mysterious woman he last saw at his hotel decades earlier.

The year is 1984 and the city is Tokyo.

A young woman named Aomame follows a taxi driver's enigmatic suggestion and begins to notice puzzling discrepancies in the world around her. She has entered, she realizes, a parallel existence, which she calls 1Q84 - "Q" is for "question mark". A world that bears a question....

In the high-fashion world of the mid-'80s, Ashleigh McDowell falls victim to a painful betrayal by Danielle Norman, a naive and vulnerable young buyer who is fighting to save her plummeting career. How high a price will both women pay in their battle over a grave secret? Each step Ashleigh takes to uncover the truth about Danielle's actions - and her whereabouts - unwittingly exposes her to a criminal mastermind who feels events spinning out of his control.

Sonea, former street urchin, now a Black Magician, is horrified when her son, Lorkin, volunteers to assist Dannyl in his new role as Guild Ambassador to Sachaka, a land still ruled by cruel black magicians. When word comes that Lorkin has gone missing Sonea is desperate to find him, but if she leaves the city she will be exiled forever, and besides, her old friend Cery needs her help.

San Francisco, 1938: A world’s fair is preparing to open on Treasure Island, a war is brewing overseas, and the city is alive with possibilities. Talented Grace, traditional Helen, and defiant Ruby, three young women from very different backgrounds, meet by chance at the exclusive and glamorous Forbidden City nightclub.

In the classic Our Haunted Planet, John A. Keel brings into chilling focus strange truths about the Earth and its mysterious inhabitants. Could an unseen, prehuman race have taken careful measures to remain hidden from surface dwellers? Are they still watching us from their secret hiding places, manipulating and misleading us, using us for their own entertainment, and controlling our actions?

There are reasons why some of the most famous serial killers in the world have names that stick in our memories, send shivers up our spines, make us double-check to make sure the doors are locked at night, and maybe peek under the bed to be sure nothing is lurking there before we turn off the lights.

With his signature wit and thought-provoking insights, Neil deGrasse Tyson - one of our foremost thinkers on all things space - illuminates the past, present, and future of space exploration and brilliantly reminds us why NASA matters now as much as ever. As Tyson reveals, exploring the space frontier can profoundly enrich many aspects of our daily lives, from education systems and the economy to national security and morale.

Even more relevant than when it was first published, this edition addresses contemporary issues in end-of-life care and includes an all-embracing and incisive afterword that examines the state of health care and our relationship with life as it approaches its terminus. How We Die also discusses how we can take control of our own final days and those of our loved ones.

Millions of people have thrilled to best-selling authors Bill O'Reilly and historian Martin Dugard's Killing Kennedy and Killing Lincoln, works of nonfiction that have changed the way we view history. Now the anchor of The O'Reilly Factor details the events leading up to the murder of the most influential man in history: Jesus of Nazareth. Nearly 2,000 years after this beloved and controversial young revolutionary was brutally killed by Roman soldiers, more than 2.2 billion human beings attempt to follow his teachings and believe he is God.

For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

In 1518, in a small town in Alsace, Frau Troffea began dancing and didn't stop. She danced until she was carried away six days later, and soon 34 more villagers joined her. Then more. In a month more than 400 people had been stricken by the mysterious dancing plague. In late-19th-century England an eccentric gentleman founded the No Nose Club in his gracious townhome - a social club for those who had lost their noses, and other body parts, to the plague of syphilis for which there was then no cure.

The remarkable stories of the world's most famous body parts. All too often, historical figures feel distant and abstract; more myth and legend than real flesh and blood. These stories of bodies and its parts remind us that history's most-loved, and most-hated, were real breathing creatures who inhabited organs and limbs just like us - until they're cut off that is. Medical historian Dr Suzie Edge investigates over 40 cases of how we've used, abused, dug up, displayed, experimented on, and worshipped body parts.

From the story of the desperate man from 17th-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers a wealth of fascinating and unforgettable insights into medicine and history via the operating room. What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell, or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?

At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.

Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

In this timely book, Steven Phillips, MD, and his former patient, Sony singer-songwriter Dana Parish, reveal striking evidence that a broad range of common infections, from COVID-19 to Lyme and many others, cause a variety of autoimmune, psychiatric, and chronic conditions. Chronic explores the science behind what makes them difficult to diagnose and treat, debunks widely held beliefs by doctors and patients alike, and provides solutions that empower sufferers to reclaim their lives.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

A puzzling series of dental explosions beginning in the 19th century is just one of many strange tales that have long lain undiscovered in the pages of old medical journals. Award-winning medical historian Thomas Morris delivers one of the most remarkable, cringe-inducing collections of stories ever assembled.

A fascinating account of the world’s most famous disease - polio - told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard-of disease began paralyzing so many children. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors?

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Galen of Pergamum (A.D. 129-ca. 216) began his remarkable career tending to wounded gladiators in provincial Asia Minor. Later in life he achieved great distinction as one of a small circle of court physicians to the family of Emperor Marcus Aurelius, at the very heart of Roman society. Susan Mattern's The Prince of Medicine offers the first authoritative biography in English of this brilliant, audacious, and profoundly influential figure.

In 1518, in a small town in Alsace, Frau Troffea began dancing and didn't stop. She danced until she was carried away six days later, and soon 34 more villagers joined her. Then more. In a month more than 400 people had been stricken by the mysterious dancing plague. In late-19th-century England an eccentric gentleman founded the No Nose Club in his gracious townhome - a social club for those who had lost their noses, and other body parts, to the plague of syphilis for which there was then no cure.

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

Each of us will know physical pain in our lives, but none of us knows when it will come or how long it will stay. Today as much as 10 percent of the population of the United States suffers from chronic pain. It is more widespread, misdiagnosed, and undertreated than any major disease. While recent research has shown that pain produces pathological changes to the brain and spinal cord, many doctors and patients still labor under misguided cultural notions and outdated scientific dogmas.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.