Lifespan
Why We Age – and Why We Don’t Have To
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Dr David A. Sinclair
About this listen
In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help listeners live younger, longer.
For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable.
But what if everything you think you know about ageing is wrong?
What if ageing is a disease? And that disease is curable.
In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.
But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Listeners will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more.
Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers LimitedCritic reviews
‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’ – Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author
‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’ – Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It!
‘In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply.’ – Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author
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What listeners say about Lifespan
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- Amazon Customer
- 11-12-19
Excellent! Loved the listen.
I would highly recommend this this audio book. I really enjoyed listening to all the latest research and understanding why things work the way they do. This book could potentially have a major impact on your life.
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1 person found this helpful
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- Setken
- 08-26-20
Human longevity science made understandable
Dr. Sinclair discsses his research and successes with longevity science, and is not afraid to give his personal opinions on the subject either - rare for scientists usually. It is in fact this human-ness that gives the book its charm, and likely why he'll be successful in sorting aging out once and for all. I believe that good people with good intentions ultimately reach their aims. I am hoping and praying that he does, for all of us.
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- Jim
- 01-07-20
Will change your life, if you let it.
A book that so many around the world should read, if only a small amount of what is in this book it's taken on by everyone around the world it will be a big step forward. Great insights and food for thought.
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1 person found this helpful
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- Anonymous User
- 01-18-23
Excellent Book
excellent book, really enjoyed it and very informative .Also well performed by author . well done
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- beinloveart
- 12-20-19
Buy the paperback for all the people you love
It’s a beautiful book to listen to; and I can see that David Sinclair will be written in the history books as the man who fought to convert 21st century medicine scholars into focusing on ageing as a disease, rather than wasting so much of each countries taxed funds on individual diseases. He makes me so proud to be an Australian. Thanks David and family.
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4 people found this helpful
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- Dinesh Senan
- 12-24-22
Eye Opening Work
This book is a MUST READ for all who love life. That ageing is a disease represents a quantum paradigm shift that will be met with much typical human mental inertia and resistance. I congratulate the author for his professional persistence and thank him for his ongoing efforts.
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- David
- 07-03-22
amazing audio well synchronized
Narrator was amazing from the begnning to the end, highly recommended.
I loved it
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- Stephen
- 10-12-20
Life-changing
The knowledge shared in this book really is life-changing. If, and that ‘if’ is becoming stronger every day, we will live to much older age with vibrancy and our wits, we have to reconsider everything, from the way we look after ourselves to the way we impact the world.
This book was very well-written, without hyperbole and embracing critical analysis. Dr Sinclair did a fabulous job of delivering the audio version as well.
This is a strong recommendation.
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- Rezma
- 02-18-20
Insightful and useful read
Must read for anyone keen to learn and apply a little more to their well being. The cutting edge information on how to optimise your health is invaluable! Can't thank Dr Sinclair enough for his efforts and generosity for sharing information.
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- Yoav
- 09-26-19
Informative and eye opening.
excellent book! comprehensive, fascinating, up to date information. begins with the science, but than sidetracks a lot to discuss philosophy and ethics (a bit too much).
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