Alice Howland is proud of the life she worked so hard to build. At 50 years old, she's a cognitive psychology professor at Harvard and a world-renowned expert in linguistics with a successful husband and three grown children. When she begins to grow disoriented and forgetful, a tragic diagnosis changes her life - and her relationship with her family and the world - forever.

Autism therapy typically focuses on ridding individuals of “autistic” symptoms such as difficulties interacting socially, problems in communicating, sensory challenges, and repetitive behavior patterns. Now Dr. Barry M. Prizant offers a new and compelling paradigm: The most successful approaches to autism don’t aim at fixing a person by eliminating symptoms, but rather seeking to understand the individual’s experience and what underlies the behavior. Rather than curb these behaviors, it’s better to enhance abilities, build on strengths, and offer supports.

In My Stroke of Insight, Taylor shares her unique perspective on the brain and its capacity for recovery, and the sense of omniscient understanding she gained from this unusual and inspiring voyage out of the abyss of a wounded brain. It would take eight years for Taylor to heal completely. Because of her knowledge of how the brain works, her respect for the cells composing her human form, and most of all an amazing mother, Taylor completely repaired her mind and recalibrated her understanding of the world.

Our finest literary interpreter of science and nature, Diane Ackerman is justly celebrated for her unique insight into the natural world and our place (for better and worse) in it.In this landmark book, she confronts the unprecedented fact that the human race is now the single dominant force of change on the planet. Humans have "subdued 75 percent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness."

Happiness begins with a charming courtship between hopelessly attracted opposites: Heather, a world-roaming California girl, and Brian, an intellectual, homebody writer, kind and slyly funny, but loath to leave his Upper West Side studio. Their magical interlude ends, full stop, when Heather becomes pregnant - Brian is sure he loves her, only he doesn't want kids. Heather returns to California to deliver their daughter alone, buoyed by family and friends.

Until John Wilson met the warm, wise woman who became his fourth wife, the object of his most intense devotion had always been the work of William Shakespeare. From his feat of memorizing Romeo and Juliet and half a dozen other plays as a student to his evangelical zeal as a professor, John's faith in the Bard has shaped his life. But now his mental powers have been diminished by dementia, and his wife has reluctantly moved him to a residential care facility.

Sands Hall chronicles her slow yet willing absorption into the Church of Scientology. Her time in the Church, the 1980s, includes the secretive illness and death of its founder, L. Ron Hubbard, and the ascension of David Miscavige. Hall compellingly reveals what drew her into the religion - what she found intriguing and useful - and how she came to confront its darker sides.

Regarded as one of the finest journalists of her generation, Mamie Baird Magnusson's whole life was a celebration of words - words that she fought to retain in the grip of a disease which is fast becoming the scourge of the 21st century. Married to writer and broadcaster Magnus Magnusson, they had five children of whom Sally is the eldest.

Hurry Down Sunshine tells the story of the extraordinary summer when, at the age of 15, Michael Greenberg's daughter was struck mad. It begins with Sally's sudden visionary crack-up on the streets of Greenwich Village, and continues, among other places, in the out-of-time world of a Manhattan psychiatric ward during the city's most sweltering months.

Celebrated children’s book author Agnes Lee is determined to secure her legacy—to complete what she knows will be the final volume of her pseudonymously written Franklin Square novels; and even more consuming, to permanently protect the peninsula of majestic coast in Maine known as Fellowship Point. To donate the land to a trust, Agnes must convince shareholders to dissolve a generations-old partnership. And one of those shareholders is her best friend, Polly.

From the moment Martha and her husband, John, conceived their second child, all hell broke loose. They were a couple obsessed with success. After years of matching IQs and test scores with less driven peers, they had two Harvard degrees apiece and were gunning for more. But the dream had begun to disintegrate. Then, when their unborn son, Adam, was diagnosed with Down syndrome, doctors, advisers, and friends in the Harvard community warned them not to keep the baby.

Everyone knows the story of Aneira Hope Jones, the woman swallowed up by a tornado, and of the painful legacy bestowed upon her children. Larken, Gaelan, and Bonnie have grown into adulthood enshrouded in myth and unresolved grief, longing for closure and for release from their identities as motherless children. Both knowingly and unknowingly, the Jones siblings have condemned themselves to the task of interpreting and paying homage to their mother's life; thus, they have never claimed their own.

Noah wants to go home. A seemingly easy request from most four-year-olds. But as Noah's single mother, Janie, knows, nothing with Noah is ever easy. One day the preschool office calls and says Janie needs to come in to talk about Noah, and no, not later, now - and life as she knows it stops. For Jerome Anderson, life as he knows it has stopped. A deadly diagnosis has made him realize he is approaching the end of his life.

The End of Miracles is a twisting, haunting story about the drastic consequences of a frustrated obsession. A woman with a complex past wants nothing more than to become a mother, but struggles with infertility and miscarriage. She is temporarily comforted by a wish-fulfilling false pregnancy, but when reality inevitably dashes that fantasy, she falls into a depression so deep she must be hospitalized.

Abby Maslin shares an inspiring story of resilience and commitment in a deeply affecting new memoir. After her husband suffered a traumatic brain injury, the couple worked together as he recovered - and they learned to love again.

From the moment Martha and her husband, John, conceived their second child, all hell broke loose. They were a couple obsessed with success. After years of matching IQs and test scores with less driven peers, they had two Harvard degrees apiece and were gunning for more. But the dream had begun to disintegrate. Then, when their unborn son, Adam, was diagnosed with Down syndrome, doctors, advisers, and friends in the Harvard community warned them not to keep the baby.

When Dorrit Wegner turned fifty, the government transferred her to a state-of-the-art facility where she can live out her days in comfort. Her apartment is furnished to her tastes, her meals expertly served, and all at the very reasonable non-negotiable price of one cardiopulmonary system. Once an outsider without family, derided by a society bent on productivity, Dorrit finds within The Unit the company of kindred spirits and a dignity conferred by 'use' in medical tests.

Charles Marlow is a Seattle English teacher who instructs his students to expand their worlds through language. Lately, however, with one child off to college and the pressure from his ex-wife to make plans for their severely autistic son who's about to age out of the system, he prefers the company of the ghosts he turns up in the storage boxes in his crawl space.

Clare Dunkle seemed to have an ideal life - two beautiful, high-achieving teenage daughters, a loving husband, and a satisfying and successful career as a children's book novelist. But it's when you let down your guard that the ax falls. Just after one daughter successfully conquered her depression, another daughter developed a life-threatening eating disorder.

Children Playing Before a Statue of Hercules is a collection of short stories, some classic, others impending, selected and introduced by David Sedaris.

When an industrial accident unleashes an "airborne toxic event", a lethal black chemical cloud floats over the Gladneys' lives. The menacing cloud is a more urgent and visible version of the "white noise" engulfing the Gladneys - radio transmissions, sirens, microwaves, ultrasonic appliances, and TV murmurings - pulsing with life yet suggesting something ominous.

In a narrative that spans geography and time, from the Atlantic Ocean in the 17th century to a correctional institute in Texas in the near future, and told from the perspectives of five very different characters, Speak considers what it means to be human and what it means to be less than fully alive.

Discover this moving story of five remarkable friends as Mary Alice Monroe, the New York Times bestselling author of The Beach House, explores the power of friendship with tenderness and honesty.

Anju and Sudha formed an astounding, almost psychic connection during their childhood in India. When Anju invites Sudha, a single mother in Calcutta, to come live with her and her husband, Sunil, in California, Sudha foolishly accepts, knowing full well that Sunil has long desired her. As Sunil's attraction rises to the surface, the trio must struggle to make sense of the freedoms of America - and of the ties that bind them to India and to one another.

Set across Istanbul and Oxford, from the 1980s to the present day, Three Daughters of Eve is a sweeping tale of faith and friendship, tradition and modernity, love and an unexpected betrayal. Peri, a wealthy Turkish housewife and mother, is on her way to a dinner party at a seaside mansion in Istanbul when a beggar snatches her handbag. As she wrestles to get it back, a photograph falls to the ground - an old polaroid of three young women and their university professor.

When Abigail Thomas’s husband, Rich, was hit by a car, his brain shattered. Subject to rages, terrors, and hallucinations, he must live the rest of his life in an institution. He has no memory of what he did the hour, the day, the year before. This tragedy is the ground on which Abigail had to build a new life. How she built that life is a story of great courage and great change, of moving to a small country town, of a new family composed of three dogs, knitting, and friendship, of facing down guilt and discovering gratitude.

An exuberant, one-of-a-kind novel about love and family, war and nature, new money and old values by a brilliant New Yorker contributor. The Portable Veblen is a dazzlingly original novel that's as big-hearted as it is laugh-out-loud funny. Set in and around Palo Alto amid the culture clash of new money and old (antiestablishment) values, and with the specter of our current wars looming across its words, The Portable Veblen is an unforgettable look at the way we live now.

His name was Kevin but his keepers called him Zoo Boy. He didn't talk. He hid under tables and surrounded himself with a cage of chairs. He hadn't been out of the building in the four years since he'd come in. He was afraid of water and wouldn't take a shower. He was afraid to be naked, to change his clothes. He was nearly 16. Desperate to see change in the boy, the staff of Kevin's adolescent treatment center hired Hayden. As Hayden read to him and encouraged him to read, crawling down into his cage of chairs with him, Kevin talked.

When Edward Schuyler - a modest and bookish 62-year-old science teacher - is widowed, he finds himself ambushed by female attention. There are plenty of unattached women around, but a healthy, handsome, available man is a rare and desirable creature. Edward receives phone calls from widows seeking love, or at least lunch, while well-meaning friends try to set him up at dinner parties. The problem is that Edward doesn’t feel available. He’s still mourning his beloved wife, Bee, and prefers solitude and the familiar routine of work, gardening, and bird-watching.

Nearly 26 years after receiving her first heart transplant, Amy Silverstein's donor heart plummeted into failure. If she wanted to live, she had to take on the grueling quest for a new heart - immediately. A shot at survival meant uprooting her life and moving across the country to California. When her friends heard of her plans, there was only one reaction: "I'm there." Nine remarkable women - Joy, Jill, Leja, Jody, Lauren, Robin, Valerie, Ann, and Jane - put demanding jobs and pressing family obligations on hold to fly across the country and be by Amy's side.