The Demon Under The Microscope
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Narrated by:
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Stephen Hoye
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By:
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Thomas Hager
About this listen
Sulfa saved millions of lives, among them, Winston Churchill's and Franklin Delano Roosevelt, Jr.'s, but its real effects have been even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold. It transformed the way doctors treated patients. And it ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness.
A strange and vibrant story, The Demon Under the Microscope illuminates the colorful characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel.
©2006 Thomas Hager (P)2006 Tantor Media, Inc.Listeners also enjoyed...
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A great scientific mystery
- By David on 11-04-06
By: D.T. Max
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The Secret History of the War on Cancer
- By: Devra Davis Ph.D.
- Narrated by: Pam Ward
- Length: 19 hrs and 11 mins
- Unabridged
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The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.
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Silly Book
- By Adam Smith on 12-24-14
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The Fantastic Laboratory of Dr. Weigl
- How Two Brave Scientists Battled Typhus and Sabotaged the Nazis
- By: Arthur Allen
- Narrated by: Dennis Holland
- Length: 10 hrs and 27 mins
- Unabridged
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Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.
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An Unforgettable book
- By Jean on 09-01-14
By: Arthur Allen
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Bellevue
- Three Centuries of Medicine and Mayhem at America's Most Storied Hospital
- By: David Oshinsky
- Narrated by: Fred Sanders
- Length: 14 hrs and 41 mins
- Unabridged
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David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.
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Fascinating
- By Jean on 12-14-16
By: David Oshinsky
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Splendid Solution
- Jonas Salk and the Conquest of Polio
- By: Jeffrey Kluger
- Narrated by: Michael Prichard
- Length: 13 hrs and 12 mins
- Unabridged
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Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.
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Excellent book
- By Tim on 08-10-06
By: Jeffrey Kluger
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Beating Back the Devil
- By: Maryn McKenna
- Narrated by: Ellen Archer
- Length: 9 hrs and 37 mins
- Unabridged
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The universal instinct is to run from an outbreak of disease. These doctors run toward it. They always keep a bag packed. They seldom have more than 24 hours before they are dispatched. They are told only their country of destination and the epidemic they will tackle when they get there.
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Interesting Stuff - Only criticism is pacing
- By Tim on 07-23-05
By: Maryn McKenna
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The Pandemic Century
- One Hundred Years of Panic, Hysteria, and Hubris
- By: Mark Honigsbaum
- Narrated by: John Lee
- Length: 13 hrs and 40 mins
- Unabridged
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Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.
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Pretty good
- By Baz 12345 on 04-03-20
By: Mark Honigsbaum
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The Moth in the Iron Lung
- A Biography of Polio
- By: Forrest Maready
- Narrated by: Forrest Maready
- Length: 5 hrs and 54 mins
- Unabridged
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A fascinating account of the world’s most famous disease - polio - told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard-of disease began paralyzing so many children. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors?
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Root Cause
- By Circlekay1 Gulfport MS on 10-24-19
By: Forrest Maready
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Asleep
- The Forgotten Epidemic That Became Medicine’s Greatest Mystery
- By: Molly Caldwell Crosby
- Narrated by: Christian Rummel
- Length: 6 hrs and 31 mins
- Unabridged
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In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.
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Scary, and still unsolved, medical mystery
- By joyce on 12-14-14
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The Butchering Art
- Joseph Lister's Quest to Transform the Grisly World of Victorian Medicine
- By: Lindsey Fitzharris
- Narrated by: Ralph Lister
- Length: 7 hrs and 54 mins
- Unabridged
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In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.
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Not one boring moment!
- By WRF on 12-22-17
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The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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Incredible
- By S.R.E. on 03-02-16
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King of Hearts
- The True Story of the Maverick Who Pioneered Open Heart Surgery
- By: G. Wayne Miller
- Narrated by: Patrick Cullen
- Length: 7 hrs and 43 mins
- Unabridged
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G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.
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Loved every minute
- By Brian on 02-05-08
By: G. Wayne Miller
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What do the reviews say about this book? Great read Very well documented book about the true Deep State shadow government controlling the United States. Every American should read this very scary expose of the CIA and its unbridled power over our government and our leaders. Excellent and revealing Easy read. Painstakingly footnoted. Every American should read this book. Vital Information This book is very well written and thoroughly researched and footnoted. I'm glad I read it, for sure. Eye opening and essential reading for all citizens. CHILLING!!! You will never see things the same way ...
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Feels incomplete
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Great Book Thoroughly Researched
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Feels incomplete
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An Epidemic of Absence
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
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The Disappearing Spoon
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Reporter Sam Kean reveals the periodic table as it’s never been seen before. Not only is it one of man's crowning scientific achievements, it's also a treasure trove of stories of passion, adventure, betrayal, and obsession. The infectious tales and astounding details in The Disappearing Spoon follow carbon, neon, silicon, and gold as they play out their parts in human history, finance, mythology, war, the arts, poison, and the lives of the (frequently) mad scientists who discovered them.
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Great Book, Great Narration, But...
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The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.
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very detailed, but very statistical
- By ekhensel15 on 01-12-19
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For years Charlie Burrell and his wife, Isabella Tree, farmed Knepp Castle Estate and struggled to turn a profit. By 2000, with the farm facing bankruptcy, they decided to try something radical. They would restore Knepp’s 3,500 acres to the wild. Using herds of free-roaming animals to mimic the actions of the megafauna of the past, they hoped to bring nature back to their depleted land. But what would the neighbors say, in the manicured countryside of modern England where a blade of grass out of place is considered an affront?
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In wildness is the preservation of the world
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Pandora’s Lab
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Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.
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Stick to the science and drop the political slant.
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Parasite Rex
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For centuries, parasites have lived in nightmares, horror stories, and the darkest shadows of science. In Parasite Rex, Carl Zimmer takes listeners on a fantastic voyage into the secret universe of these extraordinary life forms that are not only among the most highly evolved on Earth, but make up the majority of life's diversity. Traveling from the steamy jungles of Costa Rica to the parasite-riddled war zone of southern Sudan, Zimmer introduces an array of amazing creatures that invade their hosts, prey on them from within, and control their behavior.
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Fascinating and Horrible
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Plagues, Pandemics and Viruses
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It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.
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Somewhat elemental
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Never Suck a Dead Man's Hand
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Step past the flashing lights into the true scene of the crime with this frank, unflinching, and unforgettable account of life as a crime scene investigator. Whether explaining rigor mortis or the art of fingerprinting a stiff corpse on the side of the road, Dana Kollmann details her true, unvarnished experiences as a CSI for the Baltimore County Police Department.
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Overall great
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Plagues upon the Earth
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Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.
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Waste of time...endless dribble.
- By Kathleen A. Massey on 12-29-21
By: Kyle Harper
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Boone
- A Biography
- By: Robert Morgan
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Robert Morgan's Gap Creek was an Oprah's Book Club selection and a phenomenal New York Times best-seller. Here he turns his talent to chronicling the life of American frontier legend Daniel Boone.
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I am ruined for modern life
- By John on 11-21-16
By: Robert Morgan
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The Masters of Medicine
- Our Greatest Triumphs in the Race to Cure Humanity's Deadliest Diseases
- By: Andrew Lam
- Narrated by: Jason Vu
- Length: 10 hrs and 42 mins
- Unabridged
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Human history hinges on the battle to confront our most dangerous enemies—the half-dozen diseases responsible for killing almost all of mankind. The story of our medical triumphs reveals an inspiring tapestry of human achievement, but the journey was far from smooth. It is a tale replete with dramatic episodes as spellbinding as any blockbuster Hollywood movie. In The Masters of Medicine, Dr. Andrew Lam, an award-winning author and retinal surgeon, distills the long arc of medical progress down to the crucial moments that were responsible for the world's greatest medical miracles.
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Medical history comes to life
- By Clayton on 11-04-23
By: Andrew Lam
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Do No Harm
- Stories of Life, Death, and Brain Surgery
- By: Henry Marsh
- Narrated by: Jim Barclay
- Length: 9 hrs and 33 mins
- Unabridged
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With compassion and candor, leading neurosurgeon Henry Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached surgeons, this gripping, brutally honest account will make you think again.
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Uneven
- By Scott on 06-02-15
By: Henry Marsh
What listeners say about The Demon Under The Microscope
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall
- peter
- 03-06-09
Fascinating for the Science Buff
Thomas Hager has done extensive, detailed research and written his story in a concise style which makes him easy to follow. His characters are alive; the life of the scientist well described. I know of no other book which covers this subject matter; the development of the most commonly used medicines and some insight as to what life was like before this became available. Its relevance is brought to life by stories of two US Presidents' sons who became sick: one lived; one died. Absorbing detail in both cases.
Is it for everyone? Probably not. History buffs, science minded enthusiasts, medical students: I used it for some marvelous facts concerning the discovery of bacteria which parallels what is happening today in nanoscience. I can put that in PowerPoint in a second.
I have one comment for Audible, if they can do anything about it. The reader has a wonderful voice tone, speaks clearly and at the perfect speed for me. However, he has the annoying habit of dropping his tone at the end of just about every sentence or phrase, giving emphasis to the word in a way that lends sad reflection. Have you any idea how irritating this can be? I rather think it might be the same reader as ruined 'Slaughterhouse 5' for me, although the effect was a lot less intrusive in this book than there.
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14 people found this helpful
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- Rosalinda
- 04-17-15
So interesting
This is really a very good book . It surpassed my expectations. I am going to listen to it again . The narrator has a good voice
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2 people found this helpful
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- deborah
- 12-03-11
One of the Best of the Medical History Audiobooks
Well researched and narrated, this is the story of Sulfa, the pre-curser antibiotic to penicillin, and the stories of its discovery, use, and consequences for public health. Though lengthy, I finished it in two days. For those who are interested in the subject, or medical professionals, the book covers a class of drugs no longer studied. Wonderful book that had me checking wiki for further info on topics.
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- Calliope
- 10-02-16
Great book of history, medicine, and health
This is a very interesting and well-told story about something so common most people take it for granted -- antibiotics. But it's more than just the story of how the first medicine to fight bacterial infections was discovered, it's also the story of what life was like before antibiotics, how the Nazi's affected the development of medicine, and how even national boundaries affected what and how drugs were used around the world.
And it's written so well; it flows nicely and holds the readers' attention well.
There's a lot of dovetailing with Hager's "The Alchemy of Air" (also excellent, but with better narration), in that it occurs after that book but also involves the talented and innovative work of the men at Bayer in the early 20th century.
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2 people found this helpful
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Overall
- kate
- 11-09-10
Interesting topic, difficult to listen to
The subject and story are engrossing, but it was hard to listen to this narrator's overly dramatic inflections and his misproununciations. I gave up half way through.
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- Susan K Treiman
- 01-30-13
Interesting read
Fascinating tale that unfolds in the midst of wartime Germany. Although I cringed at some of the main characters' connections to the Nazis, I found the story interesting and revealing. Great delivery, too.
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- Amazon Customer
- 09-22-18
Fascinating Listen
Surprisingly easy listen with loads of interesting details. Paints the picture of early drug development and early Western medicine in a carefully thought out manner. The author does takes a few rabbit trails at times and, in my opinion, ended the book about a chapter too soon. Recommended read.
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- budsmom
- 07-01-13
Fascinating!
Would you recommend this audiobook to a friend? If so, why?
Yes, it was one of the best books I've ever read. A fascinating read!
What other book might you compare The Demon Under The Microscope to and why?
The Great Influenza because of the medical information they contain, written in an easy to understand, descriptive way.
What about Stephen Hoye’s performance did you like?
He was great. All the characters seem real and it was easy to keep them straight.
Any additional comments?
I was amazed at the lack of medical care as we know it in the US. In a country that was one of the world's leaders in inventions and innovations in the late 1800's - 1930's, it was appalling how ignorant the so called physicians were about disease, infections, and how to treat them properly. So many people died unnecessarily due to lack of sanitation and proper medicine. I was shocked to find out that doctors used many of the same methods that were used during the Middle Ages! No medical schools in the US were regulated or accredited; no research was done for anything and a man (no woman) could become a doctor with as little as 2 years of training. Almost all medical discoveries happened in Europe, Germany/France mostly. Here is where the first discoveries of molecules to produce antibiotics and antibacterials happened. This book not only explains very scientific ideas clearly, and in a way for anyone to understand.
This is the history of modern medicine as we know it today. It was not until 1937 that the first antibiotic was produced. The results amazed the world and changed the history of medicine. It is also the modern history of pharmacology. A fascinating read!
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- Cora Keegan
- 02-27-13
Great but 50% too big
What was the most interesting aspect of this story? The least interesting?
This story details how modern medicine was changed by the first antibiotics. A real eye opener especially about child birth infections and battle field surgery. The author details how dangerous and short life was before these drugs came out before world war 2. However, the book is too verbose. The details of some of the research are boring, for example in one point of the book they read off 10 minutes of numbers that were lab sample numbers, I let out a groan half way through that mind numbing detail. I took to pushing the skip 15 seconds ahead button a lot. Really about half this book could be edited out. It has a lot of details about unsuccessful experiments, some people's names and locations that don't real add much to the story.
Do you think The Demon Under The Microscope needs a follow-up book? Why or why not?
Nope, enough said.
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- Angie M.
- 06-28-15
The first miracle Drug and sacrifices to find it
Would you recommend this audiobook to a friend? If so, why?
Yes, but I would let them know it often goes very in depth in discussing the lives of the doctors and not everything is easy to listen to. This isn't a comfortable book at all times and a basic understanding of medical practices of the time is useful.
What was one of the most memorable moments of The Demon Under The Microscope?
There isn't one particular moment. There are so many people discussed in the book and their work was in concert.
Have you listened to any of Stephen Hoye’s other performances before? How does this one compare?
No this was my first. He did an excellent job in making the book interesting and giving his voice gravity when the subject matter became darker.
Was this a book you wanted to listen to all in one sitting?
No, this was a book that took some time to listen to. I had to take breaks to let things settle in my mind.
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