Someone is telling the story of the life of Charlie Barnes, and it doesn't appear to be going well. Too often divorced, discontent with life's compromises, and in a house he hates, this lifelong schemer and eternal romantic would like out of his present circumstances and into the American dream. But when the twin calamities of the Great Recession and a cancer scare come along to compound his troubles, his dreams dwindle further, and an infinite past full of forking paths quickly tapers to a black dot.

You might think laziness, lack of willpower, and/or low motivation are to blame for the fact that you aren't achieving your goals. But fascinating research in the field of psychoneuroimmunology has revealed another, far more likely possibility. One with the potential to transform your life in a dramatic way.

The Barnes family is in trouble. Dickie’s once-lucrative car business is going under—but Dickie is spending his days in the woods, building an apocalypse-proof bunker with a renegade handyman. His wife, Imelda, is selling off her jewelry on eBay and half-heartedly dodging the attention of fast-talking cattle farmer Big Mike, while their teenage daughter, Cass, formerly top of her class, seems determined to binge drink her way through her final exams. As for twelve-year-old PJ, he’s on the brink of running away.

David Sedaris' collection of essays - including live recordings! - tells a most unconventional life story. With every clever turn of a phrase, Sedaris brings a view and a voice like no other to every unforgettable encounter. You can also listen to Sedaris in an interview with Terry Gross on Fresh Air.

The hero of John Kennedy Toole's incomparable, Pultizer Prize–winning comic classic is one Ignatius J. Reilly, an obese, self-absorbed, hapless Don Quixote of the French Quarter, whose half-hearted attempts at employment lead to a series of wacky adventures among the lower denizens of New Orleans.

Wallace Stegner's uniquely American classic centers on Lyman Ward, a noted historian who relates a fictionalized biography of his pioneer grandparents at a time when he has become estranged from his own family. Through a combination of research, memory, and exaggeration, Ward voices ideas concerning the relationship between history and the present, art and life, parents and children, and husbands and wives.

Candace Chen, a millennial drone self-sequestered in a Manhattan office tower, is devoted to routine. With the recent passing of her Chinese immigrant parents, she’s had her fill of uncertainty. She’s content just to carry on: She goes to work, troubleshoots the teen-targeted Gemstone Bible, watches movies in a Greenpoint basement with her boyfriend. So Candace barely notices when a plague of biblical proportions sweeps New York.

Our narrator should be happy, shouldn't she? She's young, thin, pretty, a recent Columbia graduate; she works an easy job at a hip art gallery and lives in an apartment on the Upper East Side of Manhattan paid for, like the rest of her needs, by her inheritance. But there is a dark and vacuous hole in her heart, and it isn't just the loss of her parents, or the way her Wall Street boyfriend treats her, or her sadomasochistic relationship with her best friend, Reva. It's the year 2000 in a city aglitter with wealth and possibility; what could be so terribly wrong?

Jennifer Egan’s spellbinding interlocking narratives circle the lives of Bennie Salazar, an aging former punk rocker and record executive, and Sasha, the passionate, troubled young woman he employs. Although Bennie and Sasha never discover each other’s pasts, the listener does, in intimate detail, along with the secret lives of a host of other characters whose paths intersect with theirs, over many years, in locales as varied as New York, San Francisco, Naples, and Africa.

The Ministry for the Future is a masterpiece of the imagination, using fictional eyewitness accounts to tell the story of how climate change will affect us all. Its setting is not a desolate, post-apocalyptic world, but a future that is almost upon us - and in which we might just overcome the extraordinary challenges we face.

In a remote Polish village, Janina devotes the dark winter days to studying astrology, translating the poetry of William Blake, and taking care of the summer homes of wealthy Warsaw residents. Her reputation as a crank and a recluse is amplified by her not-so-secret preference for the company of animals over humans. Then, a neighbor, Big Foot, turns up dead. Soon, other bodies are discovered, in increasingly strange circumstances. As suspicions mount, Janina inserts herself into the investigation, certain that she knows whodunit. If only anyone would pay her mind....

"You've long set your heart against it, Axl, I know. But it's time now to think on it anew. There's a journey we must go on, and no more delay..." The Buried Giant begins as a couple set off across a troubled land of mist and rain in the hope of finding a son they have not seen in years. Sometimes savage, often intensely moving, Kazuo Ishiguro's first novel in nearly a decade is about lost memories, love, revenge, and war.

Is it possible to write a sidesplitting novel about the breakup of the perfect marriage? If the writer is Nora Ephron, the answer is a resounding yes. For in this inspired confection of adultery, revenge, group therapy, and pot roast, the creator of Sleepless in Seattle reminds us that comedy depends on anguish as surely as a proper gravy depends on flour and butter.

The richest, most depraved man on Earth, Malachi Constant, is offered a chance to take a space journey to distant worlds with a beautiful woman at his side. Of course, there's a catch to the invitation....

Blindsided by her mother’s sudden death and wrecked by a recent love affair, Casey Peabody has arrived in Massachusetts in the summer of 1997 without a plan. Her mail consists of wedding invitations and final notices from debt collectors. A former child golf prodigy, she now waits tables in Harvard Square and rents a tiny, moldy room at the side of a garage where she works on the novel she has been writing for six years. At 31, Casey is still clutching onto something nearly all her old friends have let go of: the determination to live a creative life.

The tragicomedy of a young man in New York City, a writer, never named, who works as a fact-checker for a prestigious magazine. He struggles with the reality of his mother's death, alienation, and the seductive pull of drugs and a vibrant nightlife.

Rosa Guerrero beat the odds as she rose to the top of the corporate world. An attractive woman of a certain age, the longtime chief of human resources at Ellery Consumer Research is still a formidable presence, even if her most vital days are behind her. A leader who wields power with grace and discretion, she has earned the devotion and loyalty of her staff. No one admires Rosa more than her doting lieutenant Leo Smalls, a benefits vice president whose whole world is Ellery.

Tom Violet always thought that by the time he turned 35, he’d have everything going for him. Fame. Fortune. A beautiful wife. A satisfying career as a successful novelist. A happy dog to greet him at the end of the day. The reality, though, is far different. He’s got a wife, but their problems are bigger than he can even imagine. And he’s written a novel, but the manuscript he’s slaved over for years is currently hidden in his desk drawer while his father, an actual famous writer, just won the Pulitzer Prize for Fiction. His career, such that it is, involves mind-numbing corporate buzzwords....

It’s 2005. Nick Farmer is a 35-year-old bond trader with Bear Stearns clearing seven figures a year. The novelty of a work-related nightlife centering on liquor, hookers, and cocaine has long since worn thin, though Nick remains keenly addicted to his annual bonus. But the lifestyle is taking a toll on his marriage and on him.

Davie—an ugly duckling growing up in small-town Mississippi—is positive her life couldn’t be any worse. She has the meanest mother in the South, possibly the world, and on top of that, she’s pretty sure she’s ugly. Just when she’s resigned herself to her fate, she sees a movie that will change her life— Sixteen Candles. But in her case, life doesn’t imitate art.

Yates movingly portrays a man and a woman from their courtship in the 1950s to their divorce in the '70s, chronicling their heartbreaking attempts to reach their highest ambitions. Michael Davenport dreams of being a poet after returning home from World War II, and at first he and his new wife, Lucy, enjoy their life together. But as the decades pass and the success of others creates a fear of failure in both Michael and Lucy, their once bright future gives way to a life of adultery and isolation.

To all appearances, John Wilder has all the trappings of success, circa 1960: a promising career in advertising, a loving family, a beautiful apartment, even a country home. John's evenings are spent with associates at quiet Manhattan lounges and his weekends with friends at glittering cocktail parties. But something deep within this seemingly perfect life has long since gone wrong.

Happily married Brooke discovers her loving husband has led a separate life with…another wife. Newlywed Samantha learns of her husband's cheating heart when she finds the goods on his computer. High-powered career woman Katherine works with heartbreaker Phillip, the man who hurt her early on in her career. Brooke, Samantha, and Katherine don't know one another, but their stories are about to intertwine in ways no one could have imagined. And all three are about to discover the power of friendship to conquer adversity.

Disillusioned newspaper reporter-turned-private detective Ray Dudgeon doesn't want to save the world; he just wants to do an honest job well. But when doing an honest job threatens society's most powerful and corrupt, Ray's odds of survival make for a sucker's bet.

Alan Gregory is a clinical psychologist with a thriving practice in Boulder, Colorado. His life begins to unravel when one of his female patients is found in an apparent suicide and the local paper begins printing accusations from an unnamed source of sexual impropriety between the woman and Dr. Gregory. He launches a psychological and personal quest for the truth that rapidly intensifies when more of his patients die untimely deaths, and Gregory suspects not only that the deaths are related but that another one of his patients may be somehow involved. Lacking facts but roused by suspicion and troubled by seemingly random acts of terror around him, Gregory starts to fear for the safety of the people he loves. The question of the inviolability of confidential disclosures made to Gregory by his patients - privileged information - becomes crucial as the psychologist pursues an unsettling romance with Lauren Crowder, a lovely deputy district attorney investigating one of the deaths. Bound to silence, Gregory follows the psychological tracks of someone he fears may be a cunning and disturbed killer, while turning to his enigmatic but supportive partner, Diane Estevez, for counsel, and to his tart-tongued female urologist neighbor for support. The sinister, surprising drama unfolds against Boulder's Rocky Mountain backdrop, in the arresting natural beauty of Aspen, and in the midst of a baroque Halloween costume party in downtown Boulder. Finally, in a lonely mountain lodge enshrouded in menace, the story comes to its breathtaking climax.

Katie Connelly has lived in San Francisco all her life. Her late father made his career as an ironworker on the Golden Gate Bridge, and the many stories of him trying to save jumpers still haunt her. When she's asked to write a history about the bridge, her research uncovers a secret journal hidden in her father's desk, pages of familiar advice penned by the hand of a stranger. The scribbled words tell of a promise ring and a distant love, clues that Katie hopes may answer her own unresolved sorrow.

From behind the wheel of her car, Tess Kincaid glimpses a woman walking down a Madison, Wisconsin, street. They've never met, but Tess sees the same features every time she looks in the mirror. Tess introduces herself and discovers that she and her doppelganger, Mimi, have more than appearance in common. They even share the same birthday. Mimi - confident and outgoing where Tess is understated and shy - is convinced they're twins, separated shortly after birth. When a body is discovered in a local marsh, Tess is entangled in a search for the truth....

Charley Webb is a beautiful single mother who writes a successful and controversial column for the Palm Beach Post. She's spent years building an emotional wall against scathing critics, snooty neighbors, and her disapproving family. But when she receives a letter from Jill Rohmer, a young woman serving time on death row for the murders of three small children, her boundaries slowly begin to fade. Jill wants Charley to write her biography so that she can share the many hidden truths about the case that failed to surface during her trial.

Four bodies, each with a single bullet wound in the back of the head, stacked like cordwood in a weed-choked vacant lot: That's the front-page news facing Carter Ross, investigative reporter with the Newark Eagle-Examiner. Immediately dispatched to the scene, Carter learns that the four victims - an exotic dancer, a drug dealer, a hustler, and a mama's boy - came from different parts of the city and didn't seem to know one another.

Despite her innate ambition and summa cum laude smarts, Kate Pearson has turned into a major slacker. After being dumped by her handsome French "almost fiancé", she abandons her grad school plans and spends her days lolling on the couch, leaving her apartment only when a dog-walking gig demands it. Her friends don't know what to do other than pass tissues and hope for a comeback while her practical sister, Angela, pushes every remedy she can think of, from trapeze class to therapy to job interviews.