Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.

Three very different girls sign up as trainee nurses at a big London teaching hospital in 1934. Dora leaves her overcrowded, squalid working-class home for a better life. But has she got what it takes to keep up with other, better-educated girls? And will her hated stepfather ever let her go? Helen is born for the job; her brother is a doctor, her all-powerful mother a hospital trustee. But will Helen’s secret misery be her downfall? An aristocratic rebel, Millie’s carefree attitude will find her up in front of Matron again and again. Will she ever care enough to make a nurse? Or will she go back to the glamorous life she was born to?

Mary Doyle arrives in Dublin in 1913, doomed, she fears, to a life of domestic service. Instead, however, she finds herself deeply affected by the social and political turmoil of a fledgling nation struggling for independence. Suddenly, all that was once inevitable is no longer a certainty as she is embroiled in the very heart of the Easter Rising.

Liverpool, 1940. When her childhood sweetheart, Johnny, is killed in action, Maxine Grey loses more than her husband - she loses her best friend. Desperate to make a difference in this awful war, Maxine takes a nursing job at London’s St Thomas’ hospital. She takes comfort in the attentions of a handsome surgeon, but Edwin Blake isn’t all he seems. And as the Blitz descends on the capital, Maxine faces more heartache. When she returns to Liverpool, she harbours a secret.

East London, 1888 - a city apart. A place of shadow and light where thieves, whores, and dreamers mingle, where children play in the cobbled streets by day and a killer stalks at night, where bright hopes meet the darkest truths. Here, by the whispering waters of the Thames, Fiona Finnegan, a worker in a tea factory, hopes to own a shop one day, together with her lifelong love, Joe Bristow, a costermonger's son. With nothing but their faith in each other to spur them on, Fiona and Joe struggle, save, and sacrifice to achieve their dreams.

After four years as a military nurse, Charlotte Brown is ready to leave behind the devastation of the Great War. The daughter of a vicar, she has always been determined to dedicate her life to helping others. Moving to busy Liverpool, she throws herself into her work with those most in need, only tearing herself away for the lively dinners she enjoys with the women at her boardinghouse.

Cyril Avery is not a real Avery - or at least that's what his adoptive parents tell him. And he never will be. But if he isn't a real Avery, then who is he? Born out of wedlock to a teenage girl cast out from her rural Irish community and adopted by a well-to-do if eccentric Dublin couple via the intervention of a hunchbacked Redemptorist nun, Cyril is adrift in the world, anchored only tenuously by his heartfelt friendship with the infinitely more glamourous and dangerous Julian Woodbead.

In her own words, Stella Sweeney is just "an ordinary woman living an ordinary life with her husband and two teenage kids", working for her sister in their neighborhood beauty salon. Then one day she is struck by a serious illness that lands her in the hospital for months.

Lavender Road boasts a pawnbroker, a pub, two rows of terraced working class homes, and, at one end, the big house owned by the local brewer. When war breaks out, the lives and fortunes of the families who live in Lavender Road are changed out of all recognition.

In the idyllic small town of Tucker, Vermont, life flows at a rhythmic pace for pediatrician Paige Pfeiffer. But when Mara O'Neill, her best friend and medical partner, inexplicably kills herself, Paige's comfortable world is suddenly shattered. Temporarily caring for Mara's newly adopted baby daughter while she comes to grips with her grief, Paige clings to the hope that, in time, her orderly life will return.

In "Books and Roses", one special key opens a library, a garden, and clues to at least two lovers' fates. In "Is Your Blood as Red as This?", an unlikely key opens the heart of a student at a puppeteering school. "'Sorry' Doesn't Sweeten Her Tea" involves a "house of locks", where doors can be closed only with a key - with surprising unobservable developments. And in "If a Book Is Locked There's Probably a Good Reason for That Don't You Think", a key keeps a mystical diary locked (for good reason).

Brought to Casey as a short-term emergency placement, 14-year-old Adrianna arrives with nothing but her gratitude. Having turned herself in to a social services office some 100 miles away, she has no possessions, no English and, apparently, no history - not that she's willing to share, anyway. She is a beautiful young Polish girl, with the bearing of a ballerina, but is terrified, malnourished and unwell.

For three young boys, Liam, Patrick, and Hugo, life in Ireland of the 1960s proves to be both idyllic and flawed. Living in close proximity but leading vastly different lives, the bonds of friendship bind these young men as they grow, dream, and navigate the storms of youth.

When the Templeton family from England takes up residence in a stately home in country Australia, they set the locals talking – and with good reason. From the outside, the seven Templetons seem so bohemian, peculiar even. No one is more intrigued by the family than their neighbours, single mother Nina Donovan and her young son Tom. Before long, the two families' lives become entwined in unexpected ways.

The lives of two very different couples - an officer and his aristocratic wife, and a young soldier and his childhood sweetheart - are irrevocably intertwined and forever changed in this stunning World War I epic of love and war. Moving among Ypres, London, and Paris, this emotionally rich and evocative novel is both a powerful exploration of the lasting effects of war on those who fight - and those who don't - and a poignant testament to the enduring power of love.