Acclaimed author Jonathan Rosen’s haunting investigation of the forces that led his closest childhood friend, Michael Laudor, from the heights of brilliant promise to the forensic psychiatric hospital where he has lived since killing the woman he loved. A story about friendship, love, and the price of self-delusion, The Best Minds explores the ways in which we understand—and fail to understand—mental illness.

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

After Jim O’Connell graduated from Harvard Medical School and was nearing the end of his residency at Massachusetts General, the hospital’s chief of medicine made a proposal: Would he defer a prestigious fellowship and spend a year helping to create an organization to bring health care to homeless citizens? That year turned into O’Connell’s life’s calling. Tracy Kidder spent five years following Dr. O’Connell and his colleagues as they work with thousands of homeless patients, some of whom we meet in this illuminating book.

The Aylward women of Nenagh, Tipperary, are mad about each other, but you wouldn’t always think it. You’d have to know them to know that—in spite of what the neighbors might say about raised voices and dramatic scenes—their house is a place of peace, filled with love, a refuge from the sadness and cruelty of the world. Their story begins at an end and ends at a beginning. It involves wives and widows, gunrunners and gougers, sinners and saints. It’s a story of terrible betrayals and fierce loyalties, isolation and togetherness, of transgression, forgiveness, desire, and love.

When Diane Aziz drives her oldest son, Walter, from Los Angeles to college at UC Berkeley, it will be her last parental act before falling into a deep depression. A single mother who maintains a wishful belief that her children can attain all the things she hasn’t, she’s worked hard to secure their future in caste-driven 1980s Los Angeles, gaining them illegal entry to an affluent public school. When she enters a state hospital, her closest friend tries to keep the children safe and their mother’s dreams for them alive.

In the early 1960s, JFK declared that science would take us to the moon. He also declared that science would make the “remote reaches of the mind accessible” and cure psychiatric illness with breakthrough medications. We were walking on the moon within the decade. But today, psychiatric cures continue to elude us—as does the mind itself. Why is it that we still don’t understand how the mind works? What is the difference between the mind and the brain? And given all that we still don’t know, how can we make insightful, transformative choices about our psychiatric conditions?

In 1848, a year of international democratic revolt, a young, enslaved couple, Ellen and William Craft, achieved one of the boldest feats of self-emancipation in American history. Posing as master and slave, while sustained by their love as husband and wife, they made their escape together across more than 1,000 miles, riding out in the open on steamboats, carriages, and trains that took them from bondage in Georgia to the free states of the North.

American women—American wives—have been mostly minor characters in the literature of the Vietnam War, but in Absolution they take center stage. Tricia is a shy newlywed, married to a rising attorney on loan to navy intelligence. Charlene is a practiced corporate spouse and mother of three, a beauty and a bully. In Saigon in 1963, the two women form a wary alliance as they balance the era’s mandate to be “helpmeets” to their ambitious husbands with their own, inchoate impulse to “do good” for the people of Vietnam.

In her memoir You Could Make This Place Beautiful, poet Maggie Smith explores the disintegration of her marriage and her renewed commitment to herself in lyrical vignettes that shine, hard and clear as jewels. The book begins with one woman’s personal, particular heartbreak, but its circles widen into a reckoning with contemporary womanhood, traditional gender roles, and the power dynamics that persist even in many progressive homes.

New York Times-best-selling author Ron Powers offers a searching, richly researched narrative of the social history of mental illness in America paired with the deeply personal story of his two sons' battles with schizophrenia. From the centuries of torture of "lunatiks" at Bedlam Asylum to the infamous eugenics era to the follies of the anti-psychiatry movement to the current landscape in which too many families struggle alone to manage afflicted love ones, Powers limns our fears and myths about mental illness and the fractured public policies that have resulted.

January, 2003. Together with the usual holiday cards, an anonymous postcard is delivered to the Berest family home. On the front, a photo of the Opéra Garnier in Paris. On the back, the names of Anne Berest’s maternal great-grandparents, Ephraïm and Emma, and their children, Noémie and Jacques—all killed at Auschwitz. Fifteen years after the postcard is delivered, Anne, the heroine of this novel, is moved to discover who sent it and why.

Since publication in 1983, Surviving Schizophrenia has become the standard reference book on the disease and has helped thousands of patients, their families, and mental health professionals. In clear language, this much-praised and important book describes the nature, causes, symptoms, treatment, and course of schizophrenia and also explores living with it from both the patient's and the family's point of view. This new, completely updated sixth edition includes the latest research findings on what causes the disease, as well as information about the newest drugs for treatment.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

David Sheff's story is a first: a teenager's addiction from the parent's point of view, a real-time chronicle of the shocking descent into substance abuse and the gradual emergence into hope.

Before meth, Sheff's son, Nic, was a varsity athlete, honor student, and award-winning journalist. After meth, he was a trembling wraith who stole money from his eight-year-old brother and lived on the streets. With haunting candor, Sheff traces the first warning signs, the attempts at rehabilitation, and, at last, the way past addiction. He shows us that, whatever an addict's fate, the rest of the family must care for one another, too, lest they become addicted to addiction.

Over the course of four celebrated works of fiction and almost forty years, Richard Ford has crafted an ambitious, incisive, and singular view of American life as lived. Unconstrained, astute, provocative, often laugh-out-loud funny, Frank Bascombe is once more our guide to the great American midway.