Adverse Reactions

By: Anne Chappelle PhD and David Faulkner PhD
  • Summary

  • An interview podcast bringing you the people and stories behind the science of how biological, physical, and chemical agents may cause adverse reactions to public, animal, and environmental health. This podcast is presented by the Society of Toxicology (SOT) and hosted by SOT members Anne Chappelle and David Faulkner.


    About Anne

    After graduating from the University of Delaware with a BS in biology in 1991, Anne Chappelle accidentally found her calling when she worked a gap year in an industrial toxicology laboratory. As it turned out, toxicology was the perfect marriage of protecting both human health and the environment. She then went on to receive her PhD in pharmacology and toxicology from the (now) University of the Sciences in Philadelphia in 1997, focusing on upper respiratory tract toxicity.

    For the last 20+ years, as a toxicologist and risk assessment expert for the chemical industry, Anne has been thrilled to not work in a laboratory anymore. Along the way, she has added a few more titles: spouse; DABT; Principal of Chappelle Toxicology Consulting, LLC; occasional blogger at My Toxic Life; and most life changing (and expensive): Mom. She is thrilled to be partnered with David to add podcast co-host to the list because it gives her the opportunity to “channel my inner Terry Gross.”


    About David

    David Faulkner’s interest in science started at age five with a few Bill Nye the Science Guy VHS tapes and hasn’t diminished since. A lifelong artist and science fan, David has worked in nearly every mass communication medium to share his love of science with the world. Now, as an early career toxicologist, David is living out his dream of co-hosting a science podcast! With a budget! And a producer! And super cool guests! And an awesome co-host! David thinks Bill would be proud.

    David attended the University of Michigan, where he completed a BS in microbiology, a BA in English language (emphasis in creative writing), and an MPH in environmental health sciences, and the University of California Berkeley, where he completed a PhD in molecular toxicology under the supervision of Dr. Chris Vulpe. He has held postdoctoral appointments at the Berkeley Center for Green Chemistry and the Lawrence Berkeley National Laboratory and just started a new position as a toxicological risk assessor. He also is a full-time parent to two adorable purple velvet plants: Planthony Bourdain and Marie Planthoinette.



    Disclaimer

    The viewpoints and information presented in Adverse Reactions represent those of the participating individuals. Although the Society of Toxicology holds the copyright to the production, it does not vet or review the information presented nor does presenting and distributing the Adverse Reactions podcast represent any proposal or endorsement of any position by the Society.

    © 2025 Society of Toxicology
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Episodes
  • Testing the Waters
    Jan 13 2025

    From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.

    About the Guest
    Kari Sant, PhD, is an Associate Professor of pharmacology and toxicology in the College of Veterinary Medicine at Michigan State University. She received her Bachelor of Science in biology and environmental science, her Master of Public Health in environmental health, and her PhD in toxicology from the University of Michigan. She formerly served as an Assistant and Associate Professor in San Diego State University's School of Public Health and served on the board of directors for the Boz Institute (San Diego, California).

    Dr. Sant's research program investigates environmental toxicology using a One Health framework. She uses the zebrafish model to study developmental toxicology, with an emphasis on pancreatic organogenesis and the developmental origins of diabetes. She leads and co-leads a number of studies investigating the toxicity of water contaminants in communities and how exposures may impact embryonic and child development.

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    26 mins
  • Boom! When Evolutionary Biology and Toxicology Collide
    Jan 6 2025

    Noah Whiteman, PhD, a professor at UC Berkeley, shares his unique perspective on toxins, stemming from his background in entomology and plant-insect interactions. He explores how toxins impact the ecology and evolution of various organisms, from insects to humans, with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.

    About the Guest
    Noah Whiteman, PhD, is Professor of Genetics, Genomics, Evolution, and Development in the Department of Molecular & Cell Biology and the Department of Integrative Biology at University of California (UC) Berkeley. His laboratory focuses on understanding why and how organisms deploy toxins as weapons that they use in offense and defense. Dr. Whiteman is Co-director of the NIH T32 Genetic Dissection of Cells and Organisms Training Program that provides training to 16 PhD students in genetics.

    Dr. Whiteman conducted his dissertation research in the Galapagos Islands on co-evolution between birds and their parasites. He then completed an NIH postdoctoral fellowship at Harvard where he began to use plants as model hosts that were attacked by diverse parasites. At UC Berkeley, his laboratory focuses on how plants have evolved to produce diverse toxins as defensive shields and how insects have evolved in response to resist and even sequester them. He uses genomics and genome editing as a tool to ascertain which genetic changes are responsible for these co-evolved traits.

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    28 mins
  • Cardiovascular Risks from Low-Level Metal Mixtures
    Dec 30 2024

    Sometimes negative results can be just as interesting as positive ones. Nivetha Subramaniam, a student at McGill University, discusses her research regarding the potential cardiovascular risks from exposure to mixtures of arsenic and cadmium with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.

    About the Guest

    Nivetha Kamalavannan Subramaniam is a PhD student at McGill University in Canada. She is the recipient of the McGill Dr. Morris Karmazyn and Dr. Margaret P. Moffat Fellowship in Cardiovascular Research. The title of her PhD thesis project is "The Pro-atherogenic Effects of Arsenic and Cadmium Mixtures."

    Ms. Subramaniam serves as the Graduate Student Representative for the SOT Metals Specialty Section, and in 2023, she received the second place prize from the SOT Metals Specialty Section Student Research Award Fund.

    Send SOT thoughts on the episodes, ideas for future topics, and more.

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    27 mins

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