Cannabis Nurse Truths

By: Dr. Denise Foster
  • Summary

  • Cannabis Nurse Truths is the voice of reason in a bureaucracy of nonsense. Dr. Denise Foster, PhD, MSN, RN, CNE is a nationally-recognized expert on the medicinal use of cannabis. She teaches doctors, nurses and other educators in its use in modern medicine. We talk about all things cannabis and highlight the research that continues to indicate that cannabis is medicine. New episodes every Wednesday!
    Copyright 2024 All rights reserved.
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Episodes
  • Ep. 46 - FAAH-Out: The Curious Case of Joanne Cameron
    Dec 4 2024
    Several years ago, a medical case appeared that took the scientific and medical community by storm. A patient appeared for surgery who reported never feeling anxiety, depression, or pain, despite numerous injuries and surgeries for which she required treatment. As scientists analyzed her genetic profile, they discovered something amazing - Joanne Cameron lacked the genetic code that was responsible for transmitting pain and creating anxiety and depression. In this episode of Cannabis Nurse Truths, we examine the curious case of Joanne Cameron that has led to some very surprising research that targets this important physiological phenomenon, and drug companies are furiously developing drugs to capitalize on this incredible potential to decrease pain, anxiety, depression, and treat a number of psychological and physical disorders. One of the most incredible findings linked to this case: cannabinoids, like CBD, also enhance the natural physiological activities of the body linked to the FAAH-OUT gene, where inflammation is halted (reducing pain), while also reducing or eliminating anxiety and depression. EPISODE RESOURCES Ahn, K., Johnson, D. S., & Cravatt, B. F. (2009). Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders. Expert Opinion on Drug Discovery, 4(7), 763–784. https://pmc.ncbi.nlm.nih.gov/articles/PMC2882713/pdf/nihms-116402.pdf Bartel, S. J., Sherry, S. B., & Stewart, S. H. (2020). Self-isolation: A significant contributor to cannabis use during the COVID-19 pandemic. Substance Abuse, 41(4), 409–412. https://pubmed.ncbi.nlm.nih.gov/33044893/ Bisogno, T., & Maccarrone, M. (2013). Latest advances in the discovery of fatty acid amide hydrolase inhibitors. Expert Opinion on Drug Discovery. https://www.researchgate.net/publication/236044861_Latest_advances_in_the_discovery_of_fatty_acid_amide_hydrolase_inhibitors Boileau, I., Mansouri, E., Williams, B., Le Foll, B., Rusjan, P., Mizrahi, R., Tyndale, R. F., Huestis, M. A., Payer, D. E., Wilson, A. A., Houle, S., Kish, S. J., & Tong, J. (2016). Fatty acid amide hydrolase binding in brain of cannabis users: Imaging with the novel radiotracer [11C]CURB. Biological Psychiatry, 80(9), 691–701. https://pubmed.ncbi.nlm.nih.gov/27345297/ Bornscheuer, L., Lundin, A., Forsell, Y., Lavebratt, C., & Melas, P. A. (2023). Functional variation in the FAAH gene is directly associated with subjective well-being and indirectly associated with problematic alcohol use. Genes, 14(9), 1826. https://pubmed.ncbi.nlm.nih.gov/37761966/ Cravatt, B.F., & Lichtman, A.H. (2003). Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system. Current Opinion in Chemical Biology, 7(4), 469–475. https://pubmed.ncbi.nlm.nih.gov/12941421/ Di Marzo, V., & Petrosino, S. (2007). Endocannabinoids and the regulation of their levels in health and disease. Current Opinion in Lipidology, 18(2), 129–140. https://pubmed.ncbi.nlm.nih.gov/17353660/ D’Souza, D. C., Cortes-Briones, J., Creatura, G., Bluez, G., Thurnauer, H., Deaso, E., Bielen, K., Surti, T., Radhakrishnan, R., Gupta, A., Gupta, S., Cahill, J., Sherif, M. A., Makriyannis, A., Morgan, P. T., Ranganathan, M., & Skosnik, P. D. (2019). Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: A double-blind, placebo-controlled, parallel group, phase 2a single-site randomised controlled trial. Lancet Psychiatry, 6(1), 35–45. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(18)30427-9/abstract Girella, A., Di Bartolomeo, M., Dainese, E., Buzzelli, V., Trezza, V., & D’Addario, C. (2024). Fatty acid amide hydrolase and cannabinoid receptor type 1 genes regulation is modulated by social isolation in rats. Neurochemical Research, 49(5),1278-1290. http://www.ncbi.nlm.nih.gov/pubmed/38368587 Giuffrida, A., Leweke, F. M., Gerth, C. W., Schreiber, D., Koethe, D., Faulhaber, J., Klosterkötter, J., & Piomelli, D. (2004). Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology, 29(11), 2108–2114. https://www.nature.com/articles/1300558 Habib, A. M., Okorokov, A. L., Hill, M. N., Bras, J. T., Lee, M.-C., Li, S., Gossage, S. J., van Drimmelen, M., Morena, M.,Houlden, H., Ramirez, J. D., Bennett, D. L. H., Srivastava, D., & Cox, J. J. (2019). Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity. British Journal of Anaesthesia, 123(2), e249–e253. https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6676009&blobtype=pdf Haseltine, W.A., (2023). No pain, FAAH-OUT. Forbes. https://www.forbes.com/sites/williamhaseltine/2023/06/19/no-pain-faah-out/ Huggins, J. P., Smart, T. S., Langman, S., Taylor, L., & Young, T. (2012). An efficient randomised, placebo-controlled ...
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    1 hr
  • Ep. 45 - Cruel Consequences: Portraits of Misguided Law - With Special Guest Tamara Lyn Netzel
    Nov 27 2024

    In the schizophrenic United States of Cannabis, Americans have been denied fundamental Constitutional Rights because of their choice to use a plant. Long after court requirements are satisfied from a marijuana charge, many Americans are denied basic rights like employment, voting, housing, property, child custody, and college loans that keep them from Life, Liberty, and the Pursuit of Happiness. As the laws and regulations regarding cannabis undergo extreme transformations, Americans are still subjected to discrimination, but now, there could be a light on the horizon.

    In this episode of Cannabis Nurse Truths, we are excited to host our first poTcast guest, Tamara Lyn Netzel, a nationally-recognized cannabis advocate and author, who has just published her second book, Humans of Cannabis in a Renaissance of Hope, highlighting the struggles and successes of normal everyday Americans who have decided that cannabis is their drug - or medicine - of choice. Tamara is the founder of the non-profit 501c3 Cruel Consequences: Portraits of Misguided Law after becoming a medical cannabis advocate for treatment of her multiple sclerosis symptoms and in this episode of CNT, we discuss her journey to cannabis as medicine and her passion for cannabis advocacy.

    EPIDSODE RESOURCES

    Cruel Consequences: Portraits of Misguided Law https://cruelconsequences.org/

    Amazon: Humans of Cannabis in a Renaissance of Hope https://www.amazon.com/Humans-Cannabis-Tamara-Lyn-Netzel/dp/B0DHJH9HJV?sr=8-1

    Portraits of Misguided Law: The Human Cost of Marijuana Prohibition https://checkout.square.site/buy/RLKFXWPJQ5N4K6HDMBMBEVSL

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    1 hr and 10 mins
  • Ep. 44 - Buzz Kill: The 1937 Marijuana Tax Act
    Nov 20 2024

    In order to understand how we ended up in the schizophrenic United States of Cannabis, we have to travel back in time to when cannabis was part of the American experience. For nearly 150 years after the first colony was established in Jamestown, Virginia, cannabis was utilized for spiritual rituals, rope, fibers, textiles, bird seed, oils and medicine, both for humans and pets. Until one day, a bunch of men in business suits decided that they needed a lot of money to start a war on drugs.

    In this episode of Cannabis Nurse Truths, we take a look at the very mixed-up and unfair hijinks used by the Federal government agencies that would later also benefit from its prohibition. It is all too apparent that our federal government is seriously flawed and even worse, those government entities who created this national psychosis are still benefiting from the effects of prohibition over 80 years later.

    EPISODE RESOURCES

    Adams, E. S. (2024). Just don’t do it: Why cannabis regulations are the reason cannabis businesses are failing. Nevada Law Journal, 24(349). https://scholars.law.unlv.edu/cgi/viewcontent.cgi?article=1935&context=nlj0

    Galliher, J. F., & Walker, A. (1977). The puzzle of the social origins of the Marihuana Tax Act of 1937. Social Problems, 24(3), 367–376. https://doi.org/10.2307/800089

    Griffith, R. C. (2021). A breath of fresh air: A Constitutional amendment legalizing marijuana through an Article V Convention of the States. University of Massachusetts Law Review, 16(200), Article 2. https://scholarship.law.umassd.edu/umlr/vol16/iss2/2

    LaGuardia, F. (1944). The Laguardia Committee Report New York, USA (1944). https://rodneybarnett.net/PDF/Laguardia%20Report%201944.pdf

    Last Prisoner Project. (n.d.). Exactly how many people are locked up for weed? https://www.lastprisonerproject.org/cannabis-prisoner-scale

    National Conference of State Legislatures. (n.d.). State Medical Cannabis Laws. https://www.ncsl.org/health/state-medical-cannabis-laws?__cf_chl_tk=jj5C1HNOjfrPgfuAOfFuEtsRvbrl0ufw5tdRo54kBBk-1730819983-1.0.1.1-3WmtBp1aGo4X66bWfielCviKdPcDqEI.k1hG1LmOiH4

    National Institute on Alcohol Abuse and Alcoholism. (2024). Alcohol Use in the United States: Age Groups and Demographic Characteristics. National Institutes of Health. https://www.niaaa.nih.gov/alcohols-effects-health/alcohol-topics/alcohol-facts-and-statistics/alcohol-use-united-states-age-groups-and-demographic-characteristics

    Musto, D. F. (1972). The 1937 Marijuana Tax Act. Archives of General Psychiatry, 26, 101-108. https://static1.squarespace.com/static/54b9fbd9e4b0b6737df63e5d/t/627af393d870030771a32aa1/1652224915619/The+1937+Marijuana+Tax+Stamp+Act-Musto-1972.pdf

    Patton, D. V. (n.d.). A history of United States cannabis law. Journal of Law & Health, 34(1). https://engagedscholarship.csuohio.edu/cgi/viewcontent.cgi?article=1567&context=jlh

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    1 hr

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