En este episodio veremos la respuesta a todas estas preguntas, veras que existen matices y que en ocasiones la lógica va mas allá del punto medio. Referencias: 

Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training 

https://pubmed.ncbi.nlm.nih.gov/23338987/ 

Resistance Training to Failure vs. Not to Failure: Acute and Delayed Markers of Mechanical, Neuromuscular, and Biochemical Fatigue

https://pubmed.ncbi.nlm.nih.gov/33306589/ 

Effects of different volume-equated resistance training loading strategies on muscular adaptations in well-trained men

https://pubmed.ncbi.nlm.nih.gov/24714538/ 

Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones

 https://pubmed.ncbi.nlm.nih.gov/12436270/ 

Effects of Low- vs. High-Load Resistance Training on Muscle Strength and Hypertrophy in Well-Trained Men 

https://pubmed.ncbi.nlm.nih.gov/25853914/ 

Differential Functional Adaptations to Short-Term Low-, Moderate-, and High-Repetition Weight Training

https://www.researchgate.net/publication/232218404_Differential_Functional_Adaptations_to_Short-Term_Low-_Moderate-_and_High-Repetition_Weight_Training 

The effect of training volume and intensity on improvements in muscular strength and size in resistance-trained men https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562558/ 

Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones https://pubmed.ncbi.nlm.nih.gov/12436270/ 

The effect of training volume and intensity on improvements in muscular strength and size in resistance-trained men https://pubmed.ncbi.nlm.nih.gov/26272733/ 

Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012033 

Resistance exercise load does not determine training-mediated hypertrophic gains in young men 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404827/ 

Effects of Low- vs. High-Load Resistance Training on Muscle Strength and Hypertrophy in Well-Trained Men 

https://pubmed.ncbi.nlm.nih.gov/25853914/ 

Training to Failure and Beyond in Mainstream Resistance Exercise Programs 

https://journals.lww.com/nsca-scj/Fulltext/2010/06000/Training_to_Failure_and_Beyond_in_Mainstream.2.aspx 

Is repetition failure critical for the development of muscle hypertrophy and strength? 

https://pubmed.ncbi.nlm.nih.gov/25809472/ 

Fatigue is not a necessary stimulus for strength gains during resistance training 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1724546/ 

Training Load and Fatigue Marker Associations with Injury and Illness: A Systematic Review of Longitudinal Studies https://pubmed.ncbi.nlm.nih.gov/27677917/ 

Does Performing Different Resistance Exercises for the Same Muscle Group Induce Non-homogeneous Hypertrophy? https://pubmed.ncbi.nlm.nih.gov/33440446/ 

Effects of resistance training performed to repetition failure or non-failure on muscular strength and hypertrophy: A systematic review and meta-analysis https://pubmed.ncbi.nlm.nih.gov/33497853/