The video version of this podcast can be found here: · https://youtu.be/_QJQ6ht8v2sThis channel may make reference to guidelines produced by the "National Institute for Health and Care Excellence" in the UK, also referred to as "NICE". The content on this channel reflects my professional interpretation/summary of the guidance and I am in no way affiliated with, employed by or funded/sponsored by NICE My name is Fernando Florido (also known as Juan Fernando Florido Santana) and I am a General Practitioner in the United Kingdom. In this episode I go through a variety of guidelines and publications on hepatitis B serology in order to clarify the concept and understand the interpretation of the results. You can find links to the resources consulted in the description below. I am not giving medical advice; this video is intended for health care professionals, it is only my summary and my interpretation of the guidelines and you must use your clinical judgement. Intro / outro music: Track: Halfway Through — Broke In Summer [Audio Library Release] Music provided by Audio Library Plus Watch: https://youtu.be/aBGk6aJM3IU Free Download / Stream: https://alplus.io/halfway-through There is a podcast version of this and other videos that you can access here: Primary Care guidelines podcast: · Redcircle: https://redcircle.com/shows/primary-care-guidelines· Spotify: https://open.spotify.com/show/5BmqS0Ol16oQ7Kr1WYzupK· Apple podcasts: https://podcasts.apple.com/gb/podcast/primary-care-guidelines/id1608821148 There is a YouTube version of this and other videos that you can access here: The Practical GP YouTube Channel: https://youtube.com/@practicalgp?si=ecJGF5QCuMLQ6hrk The links to the guidance covered in this episode can be found here: NICE guideline on hepatitis B: https://www.nice.org.uk/guidance/cg165/chapter/Recommendations#assessment-and-referral-in-primary-care Hepatitis B Foundation: https://www.hepb.org/prevention-and-diagnosis/diagnosis/understanding-your-test-results/BMJ article: https://www.bmj.com/bmj/section-pdf/756691?path=/bmj/348/7957/Practice.full.pdf Hepatitis B online guidance for Primary Care (PDF): https://www.hepatitisb.uw.edu/page/primary-care-workgroup/guidanceHepatitis B online module: https://www.hepatitisb.uw.edu/go/screening-diagnosis/diagnosis-hbv/core-concept/all GP notebook: https://gpnotebook.com/en-GB/pages/trauma-medicine/hepatitis-b-serology-summary NICE guidance: https://www.nice.org.uk/guidance/ph43/chapter/Recommendations#recommendation-4-testing-for-hepatitis-b-and-c-in-primary-care WHO hepatitis recommendations (PDF): https://iris.who.int/bitstream/handle/10665/254621/9789241549981-eng.pdf Public Health England: https://www.gov.uk/government/publications/infectious-diseases-in-pregnancy-screening-programme-laboratory-handbook/results-table-and-reporting-comments-for-hepatitis-bDisclaimer: The Video Content on this channel is for educational purposes and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen on this YouTube channel. The statements made throughout this video are not to be used or relied on to diagnose, treat, cure or prevent health conditions. In addition, transmission of this Content is not intended to create, and receipt by you does not constitute, a physician-patient relationship with Dr Fernando Florido, it’s employees, agents, independent contractors, or anyone acting on behalf of Dr Fernando Florido.TranscriptIf you are listening to this podcast on YouTube, for a better experience, switch to the video version. The link is in the top right corner of the video and in the episode description.Hello and welcome, I am Fernando, a GP in the UK. Today, we will go through the interpretation of hepatitis B serology. For this, I have consulted a variety of guidelines and publications in order to clarify the concepts. You can find links to the resources consulted in the episode description. Right, let’s jump into it. To interpret hepatitis B serology, first we have to understand the viral antigens and then their corresponding antibodies. So, let’s break them down one by one.Let’s look at the antigens first. There are three antigens in the hepatitis B virus. The Hepatitis B Surface Antigen is found on, well, the surface of the hepatitis B virus. This antigen is produced during active viral replication and indicates the presence of infection, appearing in the blood both during acute and chronic infections. Then we have the Hepatitis B e Antigen, which is found between the core and the viral membrane and it is released into the bloodstream during the replication of the virus.And then, the...
