On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

In 2010, scientists led by J. Craig Venter became the first to successfully create "synthetic life" - putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

WASPs finally get their due in this stimulating history by one of the world's leading geneticists. Saxons, Vikings, and Celts is the most illuminating book yet to be written about the genetic history of Britain and Ireland. Through a systematic, ten-year DNA survey of more than 10,000 volunteers, Bryan Sykes has traced the true genetic makeup of British Islanders and their descendants.

Bill Bryson has been an enormously popular author both for his travel books and for his books on the English language. Now, this beloved comic genius turns his attention to science. Although he doesn't know anything about the subject (at first), he is eager to learn, and takes information that he gets from the world's leading experts and explains it to us in a way that makes it exciting and relevant.

Adrian Tchaikovksy's critically acclaimed stand-alone novel Children of Time is the epic story of humanity's battle for survival on a terraformed planet. Who will inherit this new Earth? The last remnants of the human race left a dying Earth, desperate to find a new home among the stars. Following in the footsteps of their ancestors, they discover the greatest treasure of the past age - a world terraformed and prepared for human life. But all is not right in this new Eden.

This is the story of the rise to national power of a desperately poor young man from the Texas Hill Country. The Path to Power reveals in extraordinary detail the genesis of the almost superhuman drive, energy, and ambition that set LBJ apart. It follows him from the Hill Country to New Deal Washington, from his boyhood through the years of the Depression to his debut as Congressman, his heartbreaking defeat in his first race for the Senate, and his attainment, nonetheless, at age 31, of the national power for which he hungered.

Here is THE book recounting the life and times of one of the most respected men in the world, Warren Buffett. The legendary Omaha investor has never written a memoir, but now he has allowed one writer, Alice Schroeder, unprecedented access to explore directly with him and with those closest to him his work, opinions, struggles, triumphs, follies, and wisdom. The result is the personally revealing and complete biography of the man known everywhere as "The Oracle of Omaha."

Tracing the extraordinary trajectory of Julius Caesar's life, Adrian Goldsworthy covers not only the great Roman emperor's accomplishments as charismatic orator, conquering general, and powerful dictator but also lesser-known chapters. Ultimately, Goldsworthy realizes the full complexity of Caesar's character and shows why his political and military leadership continues to resonate some 2,000 years later.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

alaxy. Humanity was slowly making their way out from Earth to the planets and asteroids of the Solar System, exploring and mining and founding colonies. The mining ship El Cavador is far out from Earth, in the deeps of the Kuiper Belt, beyond Pluto. Other mining ships, and the families that live on them, are few and far between this far out. So when El Cavador's telescopes pick up a fast-moving object coming in-system, it's hard to know what to make of it. It's massive and moving at a significant fraction of the speed of light.

Man’s struggle against the sea is a theme that has created some of the world’s most exciting stories. Now, in the tradition of Moby Dick comes a New York Times best seller destined to become a modern classic. Written by journalist Sebastian Junger, The Perfect Storm combines an intimate portrait of a small fishing crew with fascinating scientific data about boats and weather systems.

Nikola Tesla (1856-1943), credited as the inspiration for radio, robots, and even radar, has been called the patron saint of modern electricity. Based on original material and previously unavailable documents, this acclaimed book is the definitive biography of the man considered by many to be the founding father of modern electrical technology.

William Shakespeare, the most celebrated poet in the English language, left behind nearly a million words of text, but his biography has long been a thicket of wild supposition arranged around scant facts. With a steady hand and his trademark wit, Bill Bryson sorts through this colorful muddle to reveal the man himself.

One of the greatest physicists of the twentieth century, Richard Feynman possessed an unquenchable thirst for adventure and an unparalleled ability to tell the stories of his life. "What Do You Care What Other People Think?" is Feynman's last literary legacy, prepared with his friend and fellow drummer, Ralph Leighton.

It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.

Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.

In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.

New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.

Bayes' rule appears to be a straightforward, one-line theorem: by updating our initial beliefs with objective new information, we get a new and improved belief. To its adherents, it is an elegant statement about learning from experience. To its opponents, it is subjectivity run amok. Sharon Bertsch McGrayne here explores this controversial theorem and the human obsessions surrounding it.

Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.

The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.