
Breaking Through
My Life in Science
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Narrated by:
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Eva Magyar
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By:
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Katalin Karikó
About this listen
A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
“Katalin Karikó’s story is an inspiration.”—Bill Gates
“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry
A KIRKUS REVIEWS BEST BOOK OF THE YEAR
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
©2023 Katalin Karikó (P)2023 Random House AudioListeners also enjoyed...
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Critic reviews
“A riveting testament to resilience and the power of unwavering belief, Breaking Through charts an inspirational journey from growing up in postwar communist Hungary to transforming the world with mRNA.”—Jennifer Doudna, Nobel Prize laureate in chemistry and author of A Crack in Creation
“Katalin Karikó’s story is an inspiration. Anyone who has ever doubted that science, innovation, and persistence can change the world should read this book.”—Bill Gates, #1 New York Times bestselling author of How to Avoid a Climate Disaster
“Karikó’s proven recipe (from the creative Hungarian kitchen) for a breakthrough in science: Start with an insatiable curiosity in education and research. Then, for a few decades, look for gaps in knowledge; work hard for years to fill some of them; don’t give up because of difficulties or circumstances; and, finally, seize the opportunity to help solve one painful problem of humanity, thereby opening new horizons for the future of medicine. Bon appétit, enjoy your sweets!”—Ernő Rubik, inventor of the Rubik’s Cube and author of Cubed
“Katalin Karikó’s remarkable life story, which incidentally began not far from where I spent my childhood, inspires us not to be held back even in the face of severe difficulties. It encourages us to stay strong and follow through with important ideas that can change the world.”—Stefan Hell, Nobel Prize laureate in chemistry
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- A Killer’s Game, a Woman’s Obsession, a Dark Conspiracy
- By: Trevor Aaronson
- Narrated by: Trevor Aaronson
- Length: 4 hrs and 31 mins
- Original Recording
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Overall
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Performance
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Story
On July 4, 2022, a shooter climbed onto a rooftop in Highland Park, Illinois, and opened fire on a Fourth of July parade below, killing seven people and wounding dozens more. Prosecutors charged Robert “Bobby” Crimo III with the mass shooting. But this attack was part of something even more insidious. Bobby had created an elaborate game—complete with cryptic videos, a book of numbers, and an eerie online presence—designed to seed a conspiracy theory about the massacre.
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Interesting story and perspectives.
- By B. Felix on 02-25-25
By: Trevor Aaronson
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Maybe You Should Talk to Someone
- A Therapist, HER Therapist, and Our Lives Revealed
- By: Lori Gottlieb
- Narrated by: Brittany Pressley
- Length: 14 hrs and 21 mins
- Unabridged
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Overall
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Performance
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Story
One day, Lori Gottlieb is a therapist who helps patients in her Los Angeles practice. The next, a crisis causes her world to come crashing down. Enter Wendell, the quirky but seasoned therapist in whose office she suddenly lands. With his balding head, cardigan, and khakis, he seems to have come straight from Therapist Central Casting. Yet he will turn out to be anything but.
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It was like a hallmark movie being waterboarded into my ears for 15 hours
- By Amazon Customer on 10-01-19
By: Lori Gottlieb
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Going Infinite
- The Rise and Fall of a New Tycoon
- By: Michael Lewis
- Narrated by: Michael Lewis
- Length: 9 hrs and 35 mins
- Unabridged
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Overall
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Performance
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Story
When Michael Lewis first met him, Sam Bankman-Fried was the world’s youngest billionaire and crypto’s Gatsby. CEOs, celebrities, and leaders of small countries all vied for his time and cash after he catapulted, practically overnight, onto the Forbes billionaire list. Who was this rumpled guy in cargo shorts and limp white socks, whose eyes twitched across Zoom meetings as he played video games on the side?
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really expected more rigor from Michael Lewis
- By Wowhello on 10-04-23
By: Michael Lewis
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The Madman's Hotel
- By: Niall Breslin
- Narrated by: Niall Breslin
- Length: 4 hrs and 4 mins
- Original Recording
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Overall
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Performance
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Story
In the heart of the rolling green hills of Ireland a huge abandoned psychiatric asylum looms large and holds its secrets close, until one family fights to find the truth about their long lost great grandmother. Presented by Irish celebrity and mental health advocate Niall Breslin - this is the untold story of the quest to find patient Julia Leonard, alongside many others, who came to die in St Loman’s Hospital near Dublin. Why was Julia in St Loman’s? And what happened to her and other patients who found themselves within its walls?
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Heart felt Remembrance
- By RosaInGlousta on 11-05-24
By: Niall Breslin
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I Can't Make This Up
- Life Lessons
- By: Neil Strauss - contributor, Kevin Hart
- Narrated by: Kevin Hart
- Length: 11 hrs and 15 mins
- Unabridged
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Overall
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Performance
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Story
Superstar comedian and Hollywood box-office star Kevin Hart turns his immense talent to the written word by writing some words. Some of those words include: the, a, for, above, and even even. Put them together and you have the funniest, most heartfelt, and most inspirational memoir on survival, success, and the importance of believing in yourself since Old Yeller.
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Best Audiobook I Ever Listened To
- By Sam Clear on 07-13-17
By: Neil Strauss - contributor, and others
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The Demon Next Door
- By: Bryan Burrough
- Narrated by: Steve White
- Length: 2 hrs and 45 mins
- Unabridged
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Overall
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Performance
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Story
Best-selling author Bryan Burrough recently made a shocking discovery: The small town of Temple, Texas, where he had grown up, had harbored a dark secret. One of his high school classmates, Danny Corwin, was a vicious serial killer. In this chilling tale, Burrough raises important questions of whether serial killers can be recognized before they kill or rehabilitated after they do. It is also a story of Texas politics and power that led the good citizens of the town of Temple to enable a demon who was their worst nightmare.
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Odd narration choice
- By Amanda Fredericks on 03-08-19
By: Bryan Burrough
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Genghis Khan and the Making of the Modern World
- By: Jack Weatherford
- Narrated by: Jonathan Davis, Jack Weatherford
- Length: 14 hrs and 20 mins
- Unabridged
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Overall
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Performance
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Story
The Mongol army led by Genghis Khan subjugated more lands and people in 25 years than the Romans did in 400. In nearly every country the Mongols conquered, they brought an unprecedented rise in cultural communication, expanded trade, and a blossoming of civilization.
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Golden Horde/Platinum Listen
- By Cynthia on 12-11-13
By: Jack Weatherford
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Elvis and Me
- By: Priscilla Beaulieu Presley
- Narrated by: Priscilla Beaulieu Presley
- Length: 7 hrs and 30 mins
- Unabridged
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Overall
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Performance
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Story
The inspiration for the major motion picture Priscilla directed by Sofia Coppola, this New York Times best seller reveals the intimate story of Elvis Presley and Priscilla Presley, told by the woman who lived it.
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What a story!
- By Pen Name on 08-28-22
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Ghost
- My Thirty Years as an FBI Undercover Agent
- By: Michael R. McGowan, Ralph Pezzullo
- Narrated by: Mike Dawson
- Length: 8 hrs and 45 mins
- Unabridged
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Overall
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Performance
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Story
Within FBI field operative circles, groups of people known as “Special” by their titles alone, Michael R. McGowan is an outlier. Over the course of his career, McGowan has worked more than 50 undercover cases. In this extraordinary and unprecedented book, McGowan will take listeners through some of his biggest cases, from international drug busts to the Russian and Italian mobs to biker gangs and contract killers to corrupt unions and SWAT work. Ghost is an unparalleled view into how the FBI, through the courage of its undercover Special Agents, nails the bad guys.
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Interesting story, but narration eh
- By Ahdumb on 10-06-18
By: Michael R. McGowan, and others
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My Mom's Murder
- By: AYR Media
- Narrated by: Lauren Malloy
- Length: 6 hrs and 35 mins
- Original Recording
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Overall
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Performance
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Story
When a mysterious stranger unveils a long-hidden truth, Lauren Malloy’s life is thrown into chaos. For years, Lauren believed her mother, Lori, died of natural causes, but the shocking reality is that her loving mother was brutally murdered when Lauren was just an infant. Now, 30 years later, Lauren is on a relentless quest for justice. Over the past four years, she’s embarked on an emotional journey filled with unexpected twists, recording hundreds of hours of interviews with law enforcement, family, friends, and even potential suspects.
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The raw interviews.
- By knapper on 11-12-24
By: AYR Media
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Evil Has a Name
- The Untold Story of the Golden State Killer Investigation
- By: Paul Holes, Jim Clemente, Peter McDonnell
- Narrated by: Paul Holes, Jim Clemente
- Length: 6 hrs and 13 mins
- Original Recording
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Overall
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Performance
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Story
For his victims, for their families and for the investigators tasked with finding him, the senselessness and brutality of the Golden State Killer's acts were matched only by the powerlessness they felt at failing to uncover his identity. Then, on April 24, 2018, authorities arrested 72-year-old Joseph James DeAngelo at his home in Citrus Heights, Calif., based on DNA evidence linked to the crimes. Amazingly, it seemed, evil finally had a name. Please note: This work contains descriptions of violent crime and sexual assault and may not be suitable for all listeners.
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Audible Raises The Bar On True Crime Genre
- By R. Squyres on 11-16-18
By: Paul Holes, and others
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The Autobiography of Malcolm X
- As Told to Alex Haley
- By: Malcolm X, Alex Haley
- Narrated by: Laurence Fishburne
- Length: 16 hrs and 52 mins
- Unabridged
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Overall
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Performance
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Story
Experience a bold take on this classic autobiography as it’s performed by Oscar-nominated Laurence Fishburne. In this searing classic autobiography, originally published in 1965, Malcolm X, the Muslim leader, firebrand, and Black empowerment activist, tells the extraordinary story of his life and the growth of the Human Rights movement. His fascinating perspective on the lies and limitations of the American dream and the inherent racism in a society that denies its non-White citizens the opportunity to dream, gives extraordinary insight into the most urgent issues of our own time.
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it's Nearly perfect
- By Kerry on 09-16-20
By: Malcolm X, and others
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The Story of Grunge
- By: Michael Stewart Foley, The Great Courses
- Narrated by: Michael Stewart Foley
- Length: 3 hrs
- Original Recording
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Overall
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Performance
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Story
You can’t truly understand the last decade of the 20th century without a look at the muddy, electrifying rock music that would come to define it: grunge. For such a short-lived genre—at least in the mainstream—grunge had a lasting impact on American music and culture. It also provides a unique lens through which to examine the post-Reagan, pre-internet America of the 1990s. In the six lectures of The Story of Grunge, you’ll explore the rise and evolution of the genre, tracing it from Seattle subculture to MTV and the Billboard charts, all the way to its decline and evolution into new forms.
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A Scholarly Study of Grunge
- By Mark on 03-07-25
By: Michael Stewart Foley, and others
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Ali in Me
- By: Mercury Studios, Treefort Media
- Narrated by: Lonnie Ali, John Ramsey
- Length: 3 hrs and 31 mins
- Original Recording
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Overall
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Performance
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Story
Muhammad Ali, never afraid to express himself loudly and boldly, stays true to form in Ali in Me, an eight-part audio series that explores his life and legacy, guided by his own words through never-before-heard audio recordings. Hosted by Muhammad’s widow, Lonnie Ali, and his close friend, award-winning broadcaster John Ramsey, Ali in Me goes beyond the boxing ring to delve deeply into the extraordinary life and lasting contributions The Champ made to individuals around the world.
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He went hard on everything, especially love
- By 🔥 Phx17 🔥 on 01-31-25
By: Mercury Studios, and others
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Last Witnesses
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Didn’t Want The Book To End
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How Iceland Changed the World
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The history of Iceland began 1,200 years ago, when a frustrated Viking captain and his useless navigator ran aground in the middle of the North Atlantic. Suddenly, the island was no longer just a layover for the Arctic tern. Instead, it became a nation whose diplomats and musicians, sailors and soldiers, volcanoes and flowers, quietly altered the globe forever. How Iceland Changed the World takes readers on a tour of history, showing them how Iceland played a pivotal role in events as diverse as the French Revolution, the Moon Landing, and the foundation of Israel.
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Two victims of the infamous Cleveland kidnapper share the story of their abductions, their decade in captivity, and their final, dramatic rescue. On May 6, 2013, Amanda Berry made headlines around the world when she fled a Cleveland area home and called 911, saying: “Help me, I’m Amanda Berry...I’ve been kidnapped, and I’ve been missing for 10 years". A horrifying story rapidly unfolded. Ariel Castro, a local school bus driver, had separately lured Berry, Gina DeJesus, and Michelle Knight to his home, where he kept them chained in the basement.
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From the chef behind Momofuku and star of Netflix’s Ugly Delicious—an intimate account of the making of a chef, the story of the modern restaurant world that he helped shape, and how he discovered that success can be much harder to understand than failure. Full of grace, candor, grit, and humor, Eat a Peach chronicles David Chang’s switchback path. Along the way, Chang gives us a penetrating look at restaurant life, in which he balances his deep love for the kitchen with unflinching honesty about the industry’s history of brutishness and its uncertain future.
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So many threads coming into a wonderful tapstery.
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Live in Love
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Live in Love is a deeply personal memoir that offers inspiring guidance for anyone looking to keep romance alive, balance children and marriage, express true faith, and live a life of purpose.
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AMAZING!!!
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I Was Better Last Night
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Harvey Fierstein’s legendary career has transported him from community theater in Brooklyn, to the lights of Broadway, to the absurd excesses of Hollywood and back. He’s received accolades and awards for acting in and/or writing an incredible string of hit plays, films, and TV shows.
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Loved it
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In the Heights
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In 2008, In the Heights, a new musical from up-and-coming young artists, electrified Broadway. The show’s vibrant mix of Latin music and hip-hop captured life in Washington Heights, the Latino neighborhood in upper Manhattan. It won four Tony Awards and became an international hit, delighting audiences around the world. For the film version, director Jon M. Chu (Crazy Rich Asians) brought the story home, filming its spectacular dance numbers on location in Washington Heights.
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As always, stunning!
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By: Lin-Manuel Miranda, and others
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Hunger Makes Me a Modern Girl
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From the guitarist of the pioneering band Sleater-Kinney, the book Kim Gordon says "everyone has been waiting for" and a New York Times Notable Book of 2015 - a candid, funny, and deeply personal look at making a life - and finding yourself - in music. Before Carrie Brownstein became a music icon, she was a young girl growing up in the Pacific Northwest just as it was becoming the setting for one the most important movements in rock history.
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fussy
- By Ex on 01-09-16
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We Were Illegal
- Uncovering a Texas Family's Mythmaking and Migration
- By: Jessica Goudeau
- Narrated by: Jessica Goudeau
- Length: 12 hrs and 37 mins
- Unabridged
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Over seven generations, Jessica Goudeau’s family members were church elders, preachers, Sunday school teachers and potluck organizers. Her great-grandfather helped establish a Christian university in Abilene, Texas, which she attended along with her grandparents, parents, siblings, and cousins. Her family's legacy—a word she heard often growing up—was rooted in faithfulness, righteousness, and the hard work that built the great state of Texas.
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Very good read
- By Physicist on Violin on 08-11-24
By: Jessica Goudeau
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First
- Sandra Day O'Connor
- By: Evan Thomas
- Narrated by: Kirsten Potter
- Length: 16 hrs and 33 mins
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Overall
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She was born in 1930 in El Paso and grew up on a cattle ranch in Arizona. At a time when women were expected to be homemakers, she set her sights on Stanford University. When she graduated near the top of her law school class in 1952, no firm would even interview her. But Sandra Day O’Connor’s story is that of a woman who repeatedly shattered glass ceilings - doing so with a blend of grace, wisdom, humor, understatement, and cowgirl toughness.
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Remarkable woman, well served in this book.
- By KathrynVB on 04-05-19
By: Evan Thomas
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What You Have Heard Is True
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What You Have Heard is True is a devastating, lyrical, and visionary memoir about a young woman’s brave choice to engage with horror in order to help others. Written by one of the most gifted poets of her generation, this is the story of a woman’s radical act of empathy, and her fateful encounter with an intriguing man who changes the course of her life.
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Beautiful story
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By: Carolyn Forché
What listeners say about Breaking Through
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- Jacob Rios
- 10-29-23
a must listen
this book is a must listen. it’s so inspirational and a lesson for how life should be lived.
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- José
- 01-10-24
Inspiring
Kaitlin's memoirs go beyond her major scientific advances to tell of her search for the unknown and her determination and resilience to find it, even without knowing that doing so would save millions of lives. One of the most inspiring stories I have read, but at the same time it reveals how there is a lot to do to support talent, especially women.
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- Linda Hart
- 11-21-23
Remarkable and inspiring story of grit and perseverance
Remarkable and inspiring story of grit and perseverance. Humanity should be forever grateful. Made me wonder how many researchers, particularly women, who quit before seeing the fruits of their labor because of poor leadership in their labs. The reader's accent created the belief that the book was delivered in the author's voice.
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- Amazon Customer
- 11-08-23
Excellent book!
Excellent book! Read it. Wish everyone could read this book. It is a story of grit.
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- Mai Ceesay
- 01-08-24
Phenomenal
Phenomenal and very inspirational. Just wow! Went through several rounds of smiles and cries listening to this book. Thank you for your contribution Dr.!!!
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- Lisa
- 04-06-24
inspiring story
shows how academia works, and how humanity almost missed the contributions of this wonderful scientist.
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- M. Colombo
- 06-02-24
Truly inspiriring
This is an amazing book. Katalin life is truly inspiring. The book it’s well written and well narrated. A Nobel price winner who had to face so many challenges.
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- Stacey
- 08-06-24
Absolutely remarkable!
This is an amazing autobiography by a skilled and determined researcher. She overcame many obstacles to achieve her discoveries and it is fortunate for humanity that she did so, considering how instrumental they were in developing a Covid vaccine. Brava!
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- Josh
- 11-23-24
Love letter to RNA
I enjoyed hearing about this author’s dogged determination in the face of adversity. Her story is inspiring. I admire Katalin Karikó, her voice desperately needs to be heard by the world.
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- Fox2
- 11-27-23
Excellent book
Worthy book to read. Great story that shows the ethics and hard work of Dr. Kariko. Very inspiring and it shows the importance of science in our society. I fully recommend it.
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