Eleven-year-old Anna has lived all her life with severe epilepsy. Despite the ravage of thousands of violent seizures and heavy medications, she has thrived at school, athletics, and her greatest passion—dance. As she approaches her twelfth birthday, Anna's condition takes a dire turn. Her health declines quickly and a new diagnosis is revealed, leaving the family only one excruciating choice.

What happens when things don't go as planned? What happens when the storm you face is completely out of your control? The Buchanans' precious son Christian was born with a medical condition that is so incredibly unique, it's one of only 50 known cases in the world. This story has captured the hearts of hundreds of thousands.

“Pat, we need to kill the dog.” When a sudden mental illness struck his wife, Patrick Dylan found himself living with an eerie stranger. Scared and unprepared, he began a desperate battle to protect her from a mysterious disease, shelter their children from her bizarre behavior, and recover the woman he loved. Within weeks, she had been admitted to the emergency room, the hospital, and the local crisis facility, but none of the experts could provide an answer. As her illness eluded diagnosis, the family’s struggle was only beginning.

When Schuyler Rummel-Hudson was 18 months old, a question about her lack of speech by her pediatrician set in motion a journey that continues today. When she was diagnosed with bilateral perisylvian polymicrogyria (an extremely rare neurological disorder), her parents were given a name for the monster that had been stalking them from doctor to doctor, and from despair to hope, and back again.

When Kate Swenson’s son Cooper was diagnosed with severe, nonverbal autism, her world stopped. She had always dreamed of having the perfect family life. She hadn’t signed up for life as a mother raising a child with a disability.

Oprah Winfrey has called him an inspiration, Maya Angelou saw him as a kindred spirit and fellow poet, and Jimmy Carter described Mattie Stepanek as the "most remarkable person I have ever known". When Jerry Lewis received his lifetime achievement award at the Oscars, footage of Mattie played behind him. Five years after his death from a rare neuromuscular disease, Mattie is still being celebrated for his indomitable spirit and message of hope.

"There is really no better indicator you're a mother than acquiring the ability to catch throw-up in a plastic bag, disinfect your hands, and immediately ask your friend to pass the beef jerky as you put on another Taylor Swift song and act as if nothing has happened." This is the type of insight Melanie Shankle offers in this quirky memoir of motherhood.

Teresa Rhyne vowed to get things right this time around: new boyfriend, new house, new dog, maybe even new job. But shortly after she adopted Seamus, a totally incorrigible beagle, vets told Teresa that he had a malignant tumor and less than a year to live. The diagnosis devastated her, but she decided to fight it, learning everything she could about the best treatment for Seamus. Teresa couldn't possibly have known then that she was preparing herself for life's next hurdle - a cancer diagnosis of her own.

Special Heart is a deeply touching personal story told through the eyes of a journalist as he faces the most daunting challenge in life - far more frightening than reporting from battlefields, infinitely more momentous than interviewing newsmakers of the day: caring for his critically ill newborn son. Baier reflects on past challenges as he looks forward with hope, chronicling the steps on his path to national prominence as a television anchor, as well as his unexpected journey into the world of pediatric cardiac disease.

Part inspirational cancer-survival story, part memoir-as-laugh-riot, Fran Drescher's new book picks up where Enter Whining left off. After her marriage ended, her TV series was cancelled, and her beloved dog died, Fran started having symptoms no doctor could adequately explain. With her trademark humor, she tells of her tireless search for answers and the cancer diagnosis that she ultimately beat.

"I have breast cancer." When Good Morning America anchor Amy Robach revealed her shocking diagnosis on live television in November 2013, the seasoned news reporter embarked on the most difficult and illuminating journey of her life. In this intimate memoir, she retraces the 12 months following her announcement and speaks candidly, for the first time, about how her illness affected her family life and her marriage, tapped in to her deepest fears and strengths, and transformed her in ways she never could have imagined.

After being diagnosed in her early forties with metastatic melanoma - a "rapidly fatal" form of cancer - journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own - with very different results.

Abby Maslin shares an inspiring story of resilience and commitment in a deeply affecting new memoir. After her husband suffered a traumatic brain injury, the couple worked together as he recovered - and they learned to love again.

What can you do when your well-laid plans fall apart and life takes an unexpected turn? Brenda Warner is best known as the outspoken wife of NFL superstar and Dancing with the Stars alum Kurt Warner. But years earlier, she found herself living through any woman’s nightmare: a healthy baby tragically injured in the bathtub; a sudden end to a career she loved; betrayal and divorce; poverty; public humiliation; a deadly natural disaster that destroyed her foundation and shook her to her core. One shattering phone call at a time, Brenda Warner’s life came to resemble little of her dream.

As a daughter, mother, and friend, Mary Laura Philpott considered herself an “anxious optimist”—a natural worrier with a stubborn sense of good cheer. And while she didn’t really think she had any sort of magical protective powers, she believed in her heart that as long as she loved her people enough, she could keep them safe.