In the shadows of New York City lies forbidden North Brother Island, where the remains of a shuttered sanatorium hide the haunting memories of century-old quarantines and human experiments. The ruins conceal the scarred and beautiful Cora, imprisoned by contagions and the doctors who torment her.

Olivia McAfee knows what it feels like to start over. Her picture-perfect life—living in Boston, married to a brilliant cardiothoracic surgeon, raising their beautiful son, Asher—was upended when her husband revealed a darker side. She never imagined that she would end up back in her sleepy New Hampshire hometown, living in the house she grew up in and taking over her father’s beekeeping business. Lily Campanello is familiar with do-overs, too. When she and her mom relocate to Adams, New Hampshire, for her final year of high school, they both hope it will be a fresh start.

After Tova Sullivan’s husband died, she began working the night shift at the Sowell Bay Aquarium, mopping floors and tidying up. Keeping busy has always helped her cope, which she’s been doing since her eighteen-year-old son, Erik, mysteriously vanished on a boat in Puget Sound over thirty years ago. Tova becomes acquainted with curmudgeonly Marcellus, a giant Pacific octopus living at the aquarium. Marcellus knows more than anyone can imagine but wouldn’t dream of lifting one of his eight arms for his human captors—until he forms a remarkable friendship with Tova.

Emma Townsend. Five years old. Gray eyes. Brown hair. Missing since June. Emma is lonely. Living with her cruel mother and clueless father, Emma retreats into her own world of quiet and solitude. Sarah Walker. Successful entrepreneur. Broken-hearted. Kidnapper. Sarah has never seen a girl so precious as the gray-eyed child in a crowded airport terminal. When a second-chance encounter with Emma presents itself, Sarah takes her - far away from home. But if it’s to rescue a little girl from her damaging mother, is kidnapping wrong?

When a tragic accident leaves nurse Amelia Winn deaf, she spirals into a depression that ultimately causes her to lose everything that matters - her job; her husband, David; and her stepdaughter, Nora. Now, two years later, and with the help of her hearing dog, Stitch, she is finally getting back on her feet. But when she discovers the body of a fellow nurse in the dense bush by the river, deep in the woods near her cabin, she is plunged into a disturbing mystery that could shatter the carefully reconstructed pieces of her life all over again.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

It is midnight on the morning of Halloween, and Jen anxiously waits up for her 18-year-old son, Todd, to return home. But worries about his broken curfew transform into something much more dangerous when Todd finally emerges from the darkness. As Jen watches through the window, she sees her funny, seemingly happy teenage son stab a total stranger.

Veteran social worker Ellen Moore has seen the worst side of humanity - the vilest acts one person can commit against another. She is a fiercely dedicated children's advocate and a devoted mother and wife. But one blistering summer day, a simple moment of distraction will have repercussions that Ellen could never have imagined.

It seems like any other day. You wake up, drink a cup of coffee, and head out. But today, when you open your front door, waiting for you is a small wooden box. The contents of this mysterious box tells you the exact number of years you will live. From suburban doorsteps to desert tents, every person on every continent receives the same box. In an instant, the world is thrust into a collective frenzy. Where did these boxes come from? What do they mean? Is there truth to what they promise?

For 12-year-old Cora Landry and her friends Violet and Jordyn, it was supposed to be an ordinary sleepover - movies and Ouija and talking about boys. But when they decide to sneak out to go to the abandoned rail yard on the outskirts of town, little do they know that their innocent games will have dangerous consequences. Later that night, Cora Landry is discovered on the tracks, bloody and clinging to life, her friends nowhere to be found. Soon, their small rural town is thrust into a maelstrom. Who would want to hurt a young girl like Cora - and why?

In Shaker Heights, a placid, progressive suburb of Cleveland, everything is planned - from the layout of the winding roads to the colors of the houses to the successful lives its residents will go on to lead. And no one embodies this spirit more than Elena Richardson, whose guiding principle is playing by the rules. Enter Mia Warren - an enigmatic artist and single mother - who arrives in this idyllic bubble with her teenage daughter, Pearl, and rents a house from the Richardsons.

Lucy never confessed her love to her best friend Harlan before he passed away. Two months after his funeral, she is haunted by the power of things left unsaid. But then she receives the first of his e-mails arranged to be sent after his death. So begins the year that everything changes - Lucy's watershed year. In an e-mail, Harlan says something that consumes her: He's certain Lucy is destined for motherhood. In her grief, she suddenly rediscovers hope, journeying to Russia to adopt a four-year-old boy.

The summer of 1985 changes Reggie’s life. An awkward 13-year-old, she finds herself mixed up with the school outcasts. That same summer, a serial killer called Neptune begins kidnapping women. He leaves their severed hands on the police department steps and, five days later, displays their bodies around town. Just when Reggie needs her mother, Vera, the most, Vera’s hand is found on the steps. But after five days, there’s no body and Neptune disappears. Now, 25 years later, Reggie is a successful architect who has left her hometown and the horrific memories of that summer behind.

In the wild, when a wolf knows its time is over, when it knows it is of no more use to its pack, it may sometimes choose to slip away. Dying apart from its family, it stays proud and true to its nature. Humans aren’t so lucky. Luke Warren has spent his life researching wolves. He has written about them, studied their habits intensively, and even lived with them for extended periods of time.

Dear Anna, What I have to tell you is difficult to write, but I know it will be far more difficult for you to hear, and I'm so sorry. The unfinished letter is the only clue Tara and Emerson have to the reason behind their close friend Noelle's suicide. Everything they knew about Noelle - her calling as a midwife, her passion for causes, her love for her friends and family - described a woman who embraced life. Yet there was so much they didn't know. With the discovery of the letter and its heartbreaking secret, Noelle's friends begin to uncover the truth about this complex woman who touched each of their lives.