A podcast on DNA, diagnosing genetic conditions, optical genome mapping for diagnostic accuracy, comprehensive patient histories, and equitable genetic research participation across all ethnicities.

Dr. John Robertson and his team at Cook Children's Exercise Respiratory Center specialize in diagnosing and treating exercise-induced laryngeal obstruction (EILO) and dysfunctional breathing in children and young adults. They use the Continuous Laryngoscopy During Exercise (CLE) test, a pioneering method since 2019, to observe airway, respiratory, and cardiovascular systems during exercise. The center, founded in 2023, offers personalized treatment plans involving speech and physical therapies. Research by Dr. Andy Kreutzer aims to develop a single exercise session to diagnose EILO and other respiratory issues. The team emphasizes the importance of early diagnosis and collaboration with coaches and trainers to help athletes manage symptoms and continue their sports.

Dr. Rhem shares a promising new gene therapy for children living with Duchenne.

Childhood obesity is a significant national epidemic, with approximately 20% of children and teens in the U.S. classified as obese. This condition, if untreated, leads to severe comorbidities such as type 2 diabetes, hypertension, sleep apnea, and cardiovascular diseases, among others. Adolescents with severe obesity often carry these health issues into adulthood, doubling their risk of premature death before age 55 compared to their non-obese peers.

A look at the importance of interprofessional care to improve the outcomes of young people with leukemia, with pediatric leukemia specialists Paul Bowman, M.D. and Kenneth Heym M.D.

As the fentanyl and opioid crisis continues to grow here in the U.S., those on the frontlines have seen firsthand the impact of drug overdoses on young people, families, first responders, law enforcement and health providers. While the fight to end the flow of illicit drugs continues, there is a glimmer of hope in the lifesaving drug known as naloxone. Dr. Artee Gandhi, Dr. Shakyryn Napier, Callie Crow and Eduardo Chavez explore the life-saving importance of naloxone and the challenges that continue to face our communities.

The causes of tumors in children and young adults are different than those in adults. Yet, much of the diagnoses and treatments for pediatric patients have been based on those from adults. But thanks to great strides in research, that's changing. Dr. Anish Ray, Dr. Kelly Vallance. and Dr. Heidi Trinkman take us on a journey through research, oncology, and pharmacology and their impact on pediatric precision medicine.

Children and teens can have difficulty with bladder and bowel incontinence (leaking urine or stool), constipation, pain when using the restroom (dysuria) or pelvic pain. There are myriad reasons why kids have pelvic floor issues. This could be due to pelvic floor dysfunction, muscle imbalance or diet, Join us in a lively discussion with Cook Children’s pediatric pelvic floor therapists Caitlin Smith, MOT, OTR/L, and Kathy Manthuruthil, PT, DPT, PCS, CPST on the many causes and when to refer patients to pediatric pelvic floor rehabilitation/